(Q40241059)

18 September 2017

title

Targeting the hypoxia inducible factor pathway with mitochondrial uncouplers (English)

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18 September 2017

Rusha Thomas

1

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18 September 2017

Myoung H Kim

series ordinal

2

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18 September 2017

publication date

19 August 2006

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Molecular and Cellular Biochemistry

18 September 2017

published in

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18 September 2017

volume

296

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18 September 2017

issue

1-2

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18 September 2017

page(s)

35-44

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https://scigraph.springernature.com/pub.10.1007/s11010-006-9295-3

18 September 2017

exact match

0 references

cites work

HIFs and tumors--causes and consequences

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11010-006-9295-3

Hypoxic but not anoxic stabilization of HIF-1alpha requires mitochondrial reactive oxygen species

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11010-006-9295-3

Phosphatidylinositol 3-kinase and mek1/2 are necessary for insulin-like growth factor-I-induced vascular endothelial growth factor synthesis in prostate epithelial cells: a role for hypoxia-inducible factor-1?

21 January 2018

1 reference

12 December 2020

HIF-1 as a target for drug development

1 reference

12 December 2020

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

1 reference

12 December 2020

Mitochondrial state 3 to 4 respiration transition during Fas-mediated apoptosis controls cellular redox balance and rate of cell death.

1 reference

12 December 2020

Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha

1 reference

12 December 2020

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

12 December 2020

Up-regulation of hypoxia-inducible factor 1alpha is an early event in prostate carcinogenesis.

1 reference

12 December 2020

Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension

1 reference

12 December 2020

CBP and p300: HATs for different occasions

1 reference

12 December 2020

A conserved family of prolyl-4-hydroxylases that modify HIF

1 reference

12 December 2020

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

12 December 2020

NF-kappa B activation in tumor necrosis factor alpha-stimulated neutrophils is mediated by protein kinase Cdelta. Correlation to nuclear Ikappa Balpha

1 reference

12 December 2020

Identification of vascular endothelial growth factor (VEGF) receptor-2 (Flk-1) promoter/enhancer sequences sufficient for angioblast and endothelial cell-specific transcription in transgenic mice.

1 reference

12 December 2020

Expression and implication of hypoxia inducible factor-1alpha in prostate neoplasm

1 reference

12 December 2020

Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

1 reference

12 December 2020

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

1 reference

12 December 2020

Transcription. Oxygen sensing gets a second wind

1 reference

12 December 2020

Targeting HIF-1 for cancer therapy

1 reference

12 December 2020

Effect of desferrioxamine and metals on the hydroxylases in the oxygen sensing pathway

1 reference

12 December 2020

Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

1 reference

12 December 2020

Rottlerin inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes by uncoupling mitochondrial oxidative phosphorylation

1 reference

12 December 2020

Rottlerin sensitizes colon carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via uncoupling of the mitochondria independent of protein kinase C.

1 reference

12 December 2020

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

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12 December 2020

Rottlerin is a mitochondrial uncoupler that decreases cellular ATP levels and indirectly blocks protein kinase Cdelta tyrosine phosphorylation

1 reference

12 December 2020

Mitochondria as a pharmacological target

1 reference

12 December 2020

Increased expression of hypoxia inducible factor-1alpha in rat and human prostate cancer

1 reference

12 December 2020

Ibuprofen-mediated reduction of hypoxia-inducible factors HIF-1alpha and HIF-2alpha in prostate cancer cells.

1 reference

12 December 2020

Rottlerin, a novel protein kinase inhibitor

1 reference

12 December 2020

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

1 reference

12 December 2020

Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

1 reference

12 December 2020

Regulation of hypoxia-inducible factor-1alpha by nitric oxide through mitochondria-dependent and -independent pathways.

1 reference

12 December 2020

Role of mitochondria in the regulation of hypoxia-inducible factor-1alpha in the rat carotid body glomus cells

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12 December 2020

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

1 reference

12 December 2020

10.1007/S11010-006-9295-3

Identifiers

DOI

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18 September 2017

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