(Q40252205)

English

The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor cell colony formation.

scientific article published on 24 July 2006

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scholarly article

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27 December 2019

The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor cell colony formation (English)

1 reference

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27 December 2019

Renske D. Steenbergen

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27 December 2019

Anthony Tak-Cheung Chan

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27 December 2019

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Seng TJ

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27 December 2019

Low JS

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27 December 2019

Li H

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27 December 2019

Cui Y

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27 December 2019

Goh HK

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27 December 2019

Wong ML

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27 December 2019

Srivastava G

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Sidransky D

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27 December 2019

Califano J

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27 December 2019

Tan J

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27 December 2019

Hsieh WS

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27 December 2019

Ambinder RF

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27 December 2019

Lin X

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27 December 2019

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24 July 2006

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27 December 2019

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27 December 2019

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27 December 2019

934-944

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27 December 2019

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27 December 2019

https://scigraph.springernature.com/pub.10.1038/sj.onc.1209839

0 references

Functional evidence for a nasopharyngeal carcinoma tumor suppressor gene that maps at chromosome 3p21.3.

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Distinct profiles of critically short telomeres are a key determinant of different chromosome aberrations in immortalized human cells: whole-genome evidence from multiple cell lines.

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CpG islands in vertebrate genomes

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Two epithelial tumor cell lines (HNE-1 and HONE-1) latently infected with Epstein-Barr virus that were derived from nasopharyngeal carcinomas

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21 January 2018

Etiology of nasopharyngeal carcinoma: a review

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21 January 2018

Epigenetic inactivation of TSLC1 gene in nasopharyngeal carcinoma

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High-resolution analysis of genomic copy number alterations in bladder cancer by microarray-based comparative genomic hybridization

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Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells

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Rho GTPase-activating proteins in cell regulation

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21 January 2018

Frequent epigenetic inactivation of the RASSF1A tumor suppressor gene in Hodgkin's lymphoma

1 reference

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21 January 2018

Clonal proliferations of cells infected with Epstein-Barr virus in preinvasive lesions related to nasopharyngeal carcinoma

1 reference

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21 January 2018

Analysis of DLC-1 expression in human breast cancer.

1 reference

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21 January 2018

The candidate tumor suppressor gene BLU, located at the commonly deleted region 3p21.3, is an E2F-regulated, stress-responsive gene and inactivated by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma.

1 reference

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21 January 2018

Epstein-Barr virus in the pathogenesis of NPC.

1 reference

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21 January 2018

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

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21 January 2018

Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility

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21 January 2018

TSLC1 gene silencing in cervical cancer cell lines and cervical neoplasia

1 reference

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21 January 2018

An infrequent point mutation of the p53 gene in human nasopharyngeal carcinoma

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21 January 2018

Establishment and characterization of a new xenograft-derived human esophageal squamous cell carcinoma cell line SLMT-1 of Chinese origin.

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21 January 2018

Methylation status of the Epstein-Barr virus major latent promoter C in iatrogenic B cell lymphoproliferative disease. Application of PCR-based analysis.

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Epstein-Barr virus (EBV) and its associated human cancers--genetics, epigenetics, pathobiology and novel therapeutics.

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21 January 2018

Establishment of two immortalized nasopharyngeal epithelial cell lines using SV40 large T and HPV16E6/E7 viral oncogenes.

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21 January 2018

Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation

1 reference

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21 January 2018

The stress-responsive gene GADD45G is a functional tumor suppressor, with its response to environmental stresses frequently disrupted epigenetically in multiple tumors.

1 reference

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21 January 2018

Epidemiology of nasopharyngeal carcinoma.

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21 January 2018

Promoter hypermethylation of DLC-1, a candidate tumor suppressor gene, in several common human cancers

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21 January 2018

DLC-1 operates as a tumor suppressor gene in human non-small cell lung carcinomas

1 reference

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21 January 2018

DLC-1 gene inhibits human breast cancer cell growth and in vivo tumorigenicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209839

21 January 2018

Frequent hypermethylation of RASSF1A and TSLC1, and high viral load of Epstein-Barr Virus DNA in nasopharyngeal carcinoma and matched tumor-adjacent tissues.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209839

21 January 2018

Linkage of a nasopharyngeal carcinoma susceptibility locus to the HLA regions

1 reference

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21 January 2018

Establishment and characterization of three transplantable EBV-containing nasopharyngeal carcinomas

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7 January 2021

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Mapping of nasopharyngeal carcinoma tumor-suppressive activity to a 1.8-megabase region of chromosome band 11q13

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7 January 2021

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Genome-wide scan for familial nasopharyngeal carcinoma reveals evidence of linkage to chromosome 4

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7 January 2021

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A dual functional signal mediator showing RhoGAP and phospholipase C-delta stimulating activities

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7 January 2021

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Defective de novo methylation of viral and cellular DNA sequences in ICF syndrome cells

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Sequence variants ofDLC1 in colorectal and ovarian tumours

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A susceptibility locus at chromosome 3p21 linked to familial nasopharyngeal carcinoma

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Identifiers

10.1038/SJ.ONC.1209839

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27 December 2019

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27 December 2019

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