(Q40253188)

English

Expression of simian immunodeficiency virus Nef protein in CD4+ T cells leads to a molecular profile of viral persistence and immune evasion

scientific article published on 20 July 2006

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scholarly article

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Europe PubMed Central

PubMed publication ID

18 September 2017

Expression of simian immunodeficiency virus Nef protein in CD4+ T cells leads to a molecular profile of viral persistence and immune evasion (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

viral persistence

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Simian immunodeficiency virus

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evasion of host immune response

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based on heuristic

inferred from title

author name string

Thomas Ndolo

1

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Michael George

2

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Hau Nguyen

3

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Satya Dandekar

4

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Europe PubMed Central

PubMed publication ID

18 September 2017

language of work or name

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publication date

20 July 2006

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Europe PubMed Central

PubMed publication ID

18 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

353

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

374-387

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Characterization of a human lysophosphatidic acid acyltransferase that is encoded by a gene located in the class III region of the human major histocompatibility complex

1 reference

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Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

1 reference

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Identification of STAG1 as a key mediator of a p53-dependent apoptotic pathway

1 reference

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7 January 2021

The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling

1 reference

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7 January 2021

HIV-1 Nef protein downregulation of CD4 surface expression: relevance of the lck binding domain of CD4.

1 reference

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7 January 2021

HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization

1 reference

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7 January 2021

The N-Terminus of Nef from HIV-1/SIV Associates with a Protein Complex Containing Lck and a Serine Kinase

1 reference

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7 January 2021

A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor

1 reference

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7 January 2021

Expression of human CD1d molecules protects target cells from NK cell-mediated cytolysis.

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The murine nonclassical class I major histocompatibility complex-like CD1.1 molecule protects target cells from lymphokine-activated killer cell cytolysis

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Gene expression and viral prodution in latently infected, resting CD4+ T cells in viremic versus aviremic HIV-infected individuals

1 reference

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7 January 2021

The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells

1 reference

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7 January 2021

HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.

1 reference

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7 January 2021

Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity

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The human immunodeficiency virus transactivator Tat interacts with the RNA polymerase II holoenzyme

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Gene expression profile of HIV-1 Tat expressing cells: a close interplay between proliferative and differentiation signals

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Dynamic disruptions in nuclear envelope architecture and integrity induced by HIV-1 Vpr.

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Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

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HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25

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Deletion of calcineurin and myocyte enhancer factor 2 (MEF2) binding domain of Cabin1 results in enhanced cytokine gene expression in T cells

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Bcl-2-mediated regulation of CD69-induced apoptosis of human eosinophils: identification and characterization of a novel receptor-induced mechanism and relationship to CD95-transduced signalling

1 reference

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Large-scale monitoring of host cell gene expression during HIV-1 infection using cDNA microarrays.

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7 January 2021

High-throughput gene expression profiling indicates dysregulation of intestinal cell cycle mediators and growth factors during primary simian immunodeficiency virus infection

1 reference

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7 January 2021

Early antiretroviral therapy for simian immunodeficiency virus infection leads to mucosal CD4+ T-cell restoration and enhanced gene expression regulating mucosal repair and regeneration

1 reference

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7 January 2021

Negative regulation of mitosis in fission yeast by the shk1 interacting protein skb1 and its human homolog, Skb1Hs

1 reference

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7 January 2021

The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes

1 reference

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7 January 2021

HIV F/3' orf encodes a phosphorylated GTP-binding protein resembling an oncogene product

1 reference

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Molecular architecture of SMC proteins and the yeast cohesin complex

1 reference

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Characterization by cDNA cloning of two new human protein kinases. Evidence by sequence comparison of a new family of mammalian protein kinases

1 reference

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7 January 2021

Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling

1 reference

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7 January 2021

CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides

1 reference

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7 January 2021

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

1 reference

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7 January 2021

Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

1 reference

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7 January 2021

Elucidating effects of long-term expression of HIV-1 Nef on astrocytes by microarray, promoter, and literature analyses

1 reference

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Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner

1 reference

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7 January 2021

Association of simian immunodeficiency virus Nef with cellular serine/threonine kinases is dispensable for the development of AIDS in rhesus macaques

1 reference

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7 January 2021

Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules

1 reference

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7 January 2021

A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein

1 reference

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7 January 2021

Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis

1 reference

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Molecular cloning, expression, and chromosomal localization of the human earliest lymphocyte activation antigen AIM/CD69, a new member of the C-type animal lectin superfamily of signal-transmitting receptors

1 reference

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Transcriptional regulation of the gene encoding the human C-type lectin leukocyte receptor AIM/CD69 and functional characterization of its tumor necrosis factor-alpha-responsive elements.

1 reference

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7 January 2021

HIV-1 Vpr interacts with a human 34-kDa mov34 homologue, a cellular factor linked to the G2/M phase transition of the mammalian cell cycle

1 reference

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7 January 2021

SIV/HIV Nef recombinant virus (SHIVnef) produces simian AIDS in rhesus macaques

1 reference

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CD4 down-regulation by nef alleles isolated from human immunodeficiency virus type 1-infected individuals

1 reference

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Chfr acts with the p38 stress kinases to block entry to mitosis in mammalian cells

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Identification of G1 kinase activity for cdk6, a novel cyclin D partner

1 reference

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Identification of a host gene subset related to disease prognosis of HIV-1 infected individuals

1 reference

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7 January 2021

Simian immunodeficiency virus Nef protein delays the progression of CD4+ T cells through G1/S phase of the cell cycle

1 reference

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7 January 2021

Agonists of an ecdysone-inducible mammalian expression system inhibit Fas Ligand- and TRAIL-induced apoptosis in the human colon carcinoma cell line RKO.

1 reference

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7 January 2021

Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes

1 reference

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7 January 2021

The Nef protein of primate lentiviruses

1 reference

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HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes

1 reference

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The CD1 system: antigen-presenting molecules for T cell recognition of lipids and glycolipids

1 reference

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7 January 2021

Human immunodeficiency virus 1 Nef suppresses CD40-dependent immunoglobulin class switching in bystander B cells.

1 reference

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7 January 2021

Interactions of HIV-1 NEF with cellular signal transducing proteins

1 reference

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7 January 2021

HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail

1 reference

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7 January 2021

Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein

1 reference

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Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2

1 reference

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Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4

1 reference

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Gut mucosal T cell responses and gene expression correlate with protection against disease in long-term HIV-1-infected nonprogressors

1 reference

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Expression of the early lymphocyte activation antigen CD69, a C-type lectin, is regulated by mRNA degradation associated with AU-rich sequence motifs

1 reference

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7 January 2021

Human immunodeficiency virus type 1 Nef associates with a cellular serine kinase in T lymphocytes

1 reference

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A conserved domain and membrane targeting of Nef from HIV and SIV are required for association with a cellular serine kinase activity

1 reference

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Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

1 reference

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BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control.

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7 January 2021

Effects of HIV-1 nef on cellular gene expression profiles

1 reference

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Infection and pathogenicity of chimeric simian-human immunodeficiency viruses in macaques: determinants of high virus loads and CD4 cell killing

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7 January 2021

Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators

1 reference

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7 January 2021

Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene

1 reference

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Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein

1 reference

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7 January 2021

Simian and human immunodeficiency virus Nef proteins use different surfaces to downregulate class I major histocompatibility complex antigen expression

1 reference

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7 January 2021

HIV-1 Nef intersects the macrophage CD40L signalling pathway to promote resting-cell infection

1 reference

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7 January 2021

A novel RING finger protein, human enhancer of invasion 10, alters mitotic progression through regulation of cyclin B levels

1 reference

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Cellular gene expression upon human immunodeficiency virus type 1 infection of CD4(+)-T-cell lines

1 reference

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7 January 2021

Nef induces multiple genes involved in cholesterol synthesis and uptake in human immunodeficiency virus type 1-infected T cells

1 reference

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7 January 2021

Design and use of an inducibly activated human immunodeficiency virus type 1 Nef to study immune modulation

1 reference

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7 January 2021

PACS-1 defines a novel gene family of cytosolic sorting proteins required for trans-Golgi network localization

1 reference

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7 January 2021

SKAP-55 regulates integrin adhesion and formation of T cell-APC conjugates

1 reference

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Isolation and expression of an isoform of human CDP-diacylglycerol synthase cDNA

1 reference

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HIV-1 infection initiates changes in the expression of a wide array of genes in U937 promonocytes and HUT78 T cells

1 reference

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HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals

1 reference

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7 January 2021

SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription

1 reference

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7 January 2021

Stable expression of human immunodeficiency virus type 1 Nef confers resistance against Fas-mediated apoptosis

1 reference

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7 January 2021

Nef increases infectivity of HIV via lipid rafts

1 reference

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7 January 2021

Nef increases the synthesis of and transports cholesterol to lipid rafts and HIV-1 progeny virions

1 reference

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7 January 2021

The human immunodeficiency virus type 1 nef gene can to a large extent replace simian immunodeficiency virus nef in vivo.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Cell cycle control in fission yeast and mammals: identification of new regulatory mechanisms.

1 reference

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based on heuristic

inferred from DOI database lookup

Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4.

1 reference

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7 January 2021

based on heuristic

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Generation of a chimeric human and simian immunodeficiency virus infectious to monkey peripheral blood mononuclear cells

1 reference

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based on heuristic

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Analysis of human immunodeficiency virus type 1 nef gene sequences present in vivo

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/J.VIROL.2006.06.008

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

ResearchGate publication ID

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