(Q40255981)

English

Understanding the Mechanism of the Broad-Spectrum Antiviral Activity of Favipiravir (T-705): Key Role of the F1 Motif of the Viral Polymerase

scientific article published on 5 April 2017

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scholarly article

1 reference

Europe PubMed Central

10 December 2017

Understanding the Mechanism of the Broad-Spectrum Antiviral Activity of Favipiravir (T-705): Key Role of the F1 Motif of the Viral Polymerase (English)

1 reference

Europe PubMed Central

10 December 2017

Chikungunya virus

0 references

1 reference

based on heuristic

inferred from title

8

1 reference

Europe PubMed Central

18 September 2017

object named as

Rana Abdelnabi

1

0 references

Isabelle Imbert

object named as

Isabelle Imbert

4

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object named as

Johan Neyts

10

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3

object named as

Pieter Leyssen

1 reference

Europe PubMed Central

10 December 2017

9

object named as

Bruno Canard

1 reference

Europe PubMed Central

10 December 2017

11

object named as

Leen Delang

1 reference

Europe PubMed Central

10 December 2017

7

object named as

Mathy Froeyen

1 reference

Europe PubMed Central

10 December 2017

author name string

Ana Theresa Silveira de Morais

2

1 reference

Europe PubMed Central

10 December 2017

Stéphanie Beaucourt

5

1 reference

Europe PubMed Central

10 December 2017

Hervé Blanc

6

1 reference

Europe PubMed Central

10 December 2017

language of work or name

0 references

publication date

5 April 2017

1 reference

Europe PubMed Central

10 December 2017

Journal of Virology

1 reference

Europe PubMed Central

10 December 2017

91

1 reference

Europe PubMed Central

10 December 2017

12

1 reference

Europe PubMed Central

10 December 2017

Picornaviral polymerase structure, function, and fidelity modulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

Lethal Mutagenesis of Hepatitis C Virus Induced by Favipiravir.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

Distinct Effects of T-705 (Favipiravir) and Ribavirin on Influenza Virus Replication and Viral RNA Synthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

The Viral Polymerase Inhibitor 7-Deaza-2'-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection Model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

Biochemical Evaluation of the Inhibition Properties of Favipiravir and 2'-C-Methyl-Cytidine Triphosphates against Human and Mouse Norovirus RNA Polymerases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

Deep sequencing analysis of viral infection and evolution allows rapid and detailed characterization of viral mutant spectrum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

Favipiravir elicits antiviral mutagenesis during virus replication in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

Mutations in the chikungunya virus non-structural proteins cause resistance to favipiravir (T-705), a broad-spectrum antiviral

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

RNA-dependent RNA polymerase of Japanese encephalitis virus binds the initiator nucleotide GTP to form a mechanistically important pre-initiation state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

Favipiravir (T-705), a novel viral RNA polymerase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

Mechanism of action of T-705 ribosyl triphosphate against influenza virus RNA polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

Role of human hypoxanthine guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

The ambiguous base-pairing and high substrate efficiency of T-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

Antiviral efficacy of favipiravir against two prominent etiological agents of hantavirus pulmonary syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

T-705 (favipiravir) induces lethal mutagenesis in influenza A H1N1 viruses in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

Coxsackievirus B3 mutator strains are attenuated in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

Favipiravir (T-705) inhibits in vitro norovirus replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

Ribavirin for the treatment of chronic hepatitis C virus infection: a review of the proposed mechanisms of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

The F1 motif of dengue virus polymerase NS5 is involved in promoter-dependent RNA synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

Fidelity variants of RNA dependent RNA polymerases uncover an indirect, mutagenic activity of amiloride compounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

Structural insights into replication initiation and elongation processes by the FMDV RNA-dependent RNA polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

A quantitative stopped-flow fluorescence assay for measuring polymerase elongation rates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

Mutations in the nonstructural protein 3A confer resistance to the novel enterovirus replication inhibitor TTP-8307.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

Improved crystallization of the coxsackievirus B3 RNA-dependent RNA polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

Remote site control of an active site fidelity checkpoint in a viral RNA-dependent RNA polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

Mechanism of action of T-705 against influenza virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

17 June 2018

Dose regimen of favipiravir for Ebola virus disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446660

20 August 2018

Poliovirus RNA-dependent RNA polymerase (3D(pol)). Assembly of stable, elongation-competent complexes by using a symmetrical primer-template substrate (sym/sub)

1 reference

https://pubmed.ncbi.nlm.nih.gov/28381577

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.00487-17

1 reference

Europe PubMed Central

10 December 2017

1 reference

Europe PubMed Central

10 December 2017

1 reference

Europe PubMed Central

10 December 2017

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