(Q40262427)

24 May 2018

title

Enhanced Glycolytic Metabolism Contributes to Cardiac Dysfunction in Polymicrobial Sepsis (English)

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24 May 2018

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Zhibo Zheng

1

1 reference

24 May 2018

He Ma

2

1 reference

24 May 2018

Xia Zhang

3

1 reference

24 May 2018

Fei Tu

4

1 reference

24 May 2018

Xiaohui Wang

5

1 reference

24 May 2018

Tuanzhu Ha

6

1 reference

24 May 2018

Min Fan

7

1 reference

24 May 2018

Li Liu

8

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24 May 2018

Jingjing Xu

9

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24 May 2018

Kaijiang Yu

10

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24 May 2018

Ruitao Wang

11

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24 May 2018

John Kalbfleisch

12

1 reference

24 May 2018

Race Kao

13

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24 May 2018

David Williams

14

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24 May 2018

Chuanfu Li

15

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24 May 2018

language of work or name

English

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publication date

1 May 2017

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24 May 2018

Journal of Infectious Diseases

published in

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24 May 2018

volume

215

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24 May 2018

issue

9

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24 May 2018

page(s)

1396-1406

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24 May 2018

Opposing Effects of Fasting Metabolism on Tissue Tolerance in Bacterial and Viral Inflammation

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Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis

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Lactate Contribution to the Tumor Microenvironment: Mechanisms, Effects on Immune Cells and Therapeutic Relevance

17 June 2018

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Sirtuins Link Inflammation and Metabolism

17 June 2018

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Immunometabolism governs dendritic cell and macrophage function

17 June 2018

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Immunometabolism: Cellular Metabolism Turns Immune Regulator

17 June 2018

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Attenuation of cardiac dysfunction and remodeling of myocardial infarction by microRNA-130a are mediated by suppression of PTEN and activation of PI3K dependent signaling

17 June 2018

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Lactate kinetics in sepsis and septic shock: a review of the literature and rationale for further research

17 June 2018

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Paying the Toll for Glucose Regulation: A Central Role for TLR3.

17 June 2018

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Metabolic reprogramming in macrophages and dendritic cells in innate immunity

17 June 2018

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Blockade of the JNK signalling as a rational therapeutic approach to modulate the early and late steps of the inflammatory cascade in polymicrobial sepsis.

17 June 2018

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MKK3 mediates inflammatory response through modulation of mitochondrial function

17 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Sepsis-associated hyperlactatemia

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

The interplay between central metabolism and innate immune responses

17 June 2018

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Sirt1 deletion leads to enhanced inflammation and aggravates endotoxin-induced acute kidney injury

17 June 2018

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MKK3 regulates mitochondrial biogenesis and mitophagy in sepsis-induced lung injury.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

SIRT1 and other sirtuins in metabolism

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Epidemiology of severe sepsis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Clinical use of lactate monitoring in critically ill patients.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

17 June 2018

1 reference

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The Toll-like receptor 9 ligand, CpG oligodeoxynucleotide, attenuates cardiac dysfunction in polymicrobial sepsis, involving activation of both phosphoinositide 3 kinase/Akt and extracellular-signal-related kinase signaling

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Increased expression of microRNA-146a decreases myocardial ischaemia/reperfusion injury

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Toll-like receptor 3 plays a central role in cardiac dysfunction during polymicrobial sepsis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Myocardial dysfunction in sepsis: a large, unsolved puzzle

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

MyD88 and Trif signaling play distinct roles in cardiac dysfunction and mortality during endotoxin shock and polymicrobial sepsis.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

2-Deoxy-D-glucose treatment of endothelial cells induces autophagy by reactive oxygen species-mediated activation of the AMP-activated protein kinase

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Silent information regulator 1 protects the heart from ischemia/reperfusion

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Toll-like receptor 2 plays a critical role in cardiac dysfunction during polymicrobial sepsis.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

TLR2 ligands attenuate cardiac dysfunction in polymicrobial sepsis via a phosphoinositide 3-kinase-dependent mechanism

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Understanding the Warburg effect: the metabolic requirements of cell proliferation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Lactate boosts TLR4 signaling and NF-kappaB pathway-mediated gene transcription in macrophages via monocarboxylate transporters and MD-2 up-regulation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

The mitochondrial p53 pathway

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Mitochondrial mechanisms of sepsis-induced organ failure

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Glycolysis inhibition for anticancer treatment

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Neutrophils in development of multiple organ failure in sepsis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Apoptosis in sepsis: a new target for therapeutic exploration

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Caspase inhibition prevents cardiac dysfunction and heart apoptosis in a rat model of sepsis.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Different fate in vivo of oxidatively modified low density lipoprotein and acetylated low density lipoprotein in rats. Recognition by various scavenger receptors on Kupffer and endothelial liver cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

SIRT1 inhibits inflammatory response partly through regulation of NLRP3 inflammasome in vascular endothelial cells.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Serum lactate is associated with mortality in severe sepsis independent of organ failure and shock

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Mitochondrial dysfunction in septic shock and multiple organ dysfunction syndrome.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5451607

Incorporation of glucose into glycogen in primary cultures of rat hepatocytes

20 August 2018

1 reference

12 December 2020

Inhibition of nuclear factor-kappaB-mediated adhesion molecule expression in human endothelial cells

1 reference

12 December 2020

Glucan phosphate attenuates cardiac dysfunction and inhibits cardiac MIF expression and apoptosis in septic mice

1 reference

12 December 2020

Modulation of tissue Toll-like receptor 2 and 4 during the early phases of polymicrobial sepsis correlates with mortality

1 reference

12 December 2020

Identifiers

DOI

10.1093/INFDIS/JIX138

1 reference

24 May 2018

PMCID

5451607

1 reference

24 May 2018

PubMed ID

28368517

1 reference

24 May 2018