(Q40262851)

English

5-Aza-2'-deoxycytidine-mediated reductions in G9A histone methyltransferase and histone H3 K9 di-methylation levels are linked to tumor suppressor gene reactivation

scientific article published on 26 June 2006

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

19 September 2017

5-Aza-2'-deoxycytidine-mediated reductions in G9A histone methyltransferase and histone H3 K9 di-methylation levels are linked to tumor suppressor gene reactivation (English)

1 reference

Europe PubMed Central

19 September 2017

author name string

R J Wozniak

1

1 reference

Europe PubMed Central

19 September 2017

W T Klimecki

2

1 reference

Europe PubMed Central

19 September 2017

S S Lau

3

1 reference

Europe PubMed Central

19 September 2017

Y Feinstein

4

1 reference

Europe PubMed Central

19 September 2017

B W Futscher

5

1 reference

Europe PubMed Central

19 September 2017

language of work or name

0 references

publication date

26 June 2006

1 reference

Europe PubMed Central

19 September 2017

1 reference

Europe PubMed Central

19 September 2017

26

1 reference

Europe PubMed Central

19 September 2017

77-90

1 reference

Europe PubMed Central

19 September 2017

1

1 reference

Europe PubMed Central

19 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1209763

0 references

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Antineoplastic action of 5-aza-2'-deoxycytidine and histone deacetylase inhibitor and their effect on the expression of retinoic acid receptor beta and estrogen receptor alpha genes in breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Resetting the histone code at CDKN2A in HNSCC by inhibition of DNA methylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Epigenetic silencing of maspin gene expression in human breast cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Aberrant methylation of the maspin promoter is an early event in human breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Role for DNA methylation in the control of cell type specific maspin expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

CpG islands in vertebrate genomes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

DNMT3B interacts with hSNF2H chromatin remodeling enzyme, HDACs 1 and 2, and components of the histone methylation system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Methylation of histone H3 at Lys-9 is an early mark on the X chromosome during X inactivation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

The methyltransferase inhibitor 5-aza-2-deoxycytidine induces apoptosis via induction of 15-lipoxygenase-1 in colorectal cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Chromatin remodeling and human disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of DNA methylation in mammalian epigenetics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Decitabine dosing schedules.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Results of decitabine (5-aza-2'deoxycytidine) therapy in 130 patients with chronic myelogenous leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Reactivating the expression of methylation silenced genes in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Desmosomal cadherins: another growing multigene family of adhesion molecules

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Chromatin immunoprecipitation microarrays for identification of genes silenced by histone H3 lysine 9 methylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Characteristic promoter hypermethylation signatures in male germ cell tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytogenetic responses in high-risk myelodysplastic syndrome following low-dose treatment with the DNA methylation inhibitor 5-aza-2'-deoxycytidine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Mapping global histone methylation patterns in the coding regions of human genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential nuclear protein binding to 5-azacytosine-containing DNA as a potential mechanism for 5-aza-2'-deoxycytidine resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of differentiation and inhibition of DNA methylation in HL-60 myeloid leukemic cells by 5-AZA-2'-deoxycytidine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of DNA demethylation effects induced by 5-Aza-2'-deoxycytidine in patients with myelodysplastic syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Rb targets histone H3 methylation and HP1 to promoters

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Epigenetic silencing of DSC3 is a common event in human breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutant p53 and aberrant cytosine methylation cooperate to silence gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Promoter hypermethylation of MGMT is associated with protein loss in gastric carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Partitioning and plasticity of repressive histone methylation states in mammalian chromatin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Transcriptional repression of BRCA1 by aberrant cytosine methylation, histone hypoacetylation and chromatin condensation of the BRCA1 promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Methylation of the BRCA1 promoter is associated with decreased BRCA1 mRNA levels in clinical breast cancer specimens

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical development of decitabine as a prototype for an epigenetic drug program

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Evaluation of a 7-day continuous intravenous infusion of decitabine: inhibition of promoter-specific and global genomic DNA methylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

5-Aza-2'-deoxycytidine (decitabine) can relieve p21WAF1 repression in human acute myeloid leukemia by a mechanism involving release of histone deacetylase 1 (HDAC1) without requiring p21WAF1 promoter demethylation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Transcription initiation from TATA-less promoters within eukaryotic protein-coding genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Diverse transcriptional initiation revealed by fine, large-scale mapping of mRNA start sites

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Comprehensive analysis of CpG islands in human chromosomes 21 and 22

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Developmental characterization and chromosomal mapping of the 5-azacytidine-sensitive fluF locus of Aspergillus nidulans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

High-Frequency Conversion to a “Fluffy” Developmental Phenotype in Aspergillus spp. by 5-Azacytidine Treatment: Evidence for Involvement of a Single Nuclear Gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Clonal chromosome abnormalities in human breast carcinomas. II. Thirty-four cases with metastatic disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Low-dose 5-aza-2'-deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome: a multicenter phase II study in elderly patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased expression of unmethylated CDKN2D by 5-aza-2'-deoxycytidine in human lung cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209763

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1209763

1 reference

Europe PubMed Central

19 September 2017

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

19 September 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q40262851&oldid=1891328551"