(Q40263228)

19 September 2017

title

Grafting of thrombopoietin-mimetic peptides into cystine knot miniproteins yields high-affinity thrombopoietin antagonists and agonists (English)

1 reference

19 September 2017

Sebastian Krause

1

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19 September 2017

Hans-Ulrich Schmoldt

2

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19 September 2017

Alexander Wentzel

3

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19 September 2017

Matthias Ballmaier

4

1 reference

19 September 2017

Karlheinz Friedrich

5

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19 September 2017

Harald Kolmar

6

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19 September 2017

language of work or name

English

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publication date

27 November 2006

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19 September 2017

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19 September 2017

volume

274

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19 September 2017

issue

1

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19 September 2017

page(s)

86-95

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Rational engineering of a miniprotein that reproduces the core of the CD4 site interacting with HIV-1 envelope glycoprotein

19 September 2017

cites work

1 reference

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The cystine knot of a squash-type protease inhibitor as a structural scaffold for Escherichia coli cell surface display of conformationally constrained peptides

21 January 2018

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The potential of cystine-knot microproteins as novel pharmacophoric scaffolds in oral peptide drug delivery

21 January 2018

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Squash inhibitors: from structural motifs to macrocyclic knottins

21 January 2018

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Plant cyclotides: circular, knotted peptide toxins.

21 January 2018

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NMR structure of a minimized human agouti related protein prepared by total chemical synthesis

21 January 2018

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Current trends in the structure-activity relationship studies of the endogenous agouti-related protein (AGRP) melanocortin receptor antagonist

21 January 2018

1 reference

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High-resolution NMR structure of the chemically-synthesized melanocortin receptor binding domain AGRP(87-132) of the agouti-related protein

21 January 2018

1 reference

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Design, pharmacology, and NMR structure of a minimized cystine knot with agouti-related protein activity

21 January 2018

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The cystine knot motif in toxins and implications for drug design.

21 January 2018

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Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design.

21 January 2018

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21 January 2018

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Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin

21 January 2018

1 reference

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Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand.

21 January 2018

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Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment

21 January 2018

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Recombinant human thrombopoietin: basic biology and evaluation of clinical studies

21 January 2018

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Development of pancytopenia with neutralizing antibodies to thrombopoietin after multicycle chemotherapy supported by megakaryocyte growth and development factor

21 January 2018

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Thrombocytopenia caused by the development of antibodies to thrombopoietin

21 January 2018

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Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine

21 January 2018

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A novel therapeutic approach for thrombocytopenia by minibody agonist of the thrombopoietin receptor

21 January 2018

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Elongation studies of the human agouti-related protein (AGRP) core decapeptide (Yc[CRFFNAFC]Y) results in antagonism at the mouse melanocortin-3 receptor

21 January 2018

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Bacteria displaying interleukin-4 mutants stimulate mammalian cells and reflect the biological activities of variant soluble cytokines

21 January 2018

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Thermal, chemical, and enzymatic stability of the cyclotide kalata B1: the importance of the cyclic cystine knot.

21 January 2018

1 reference

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Engineering stable peptide toxins by means of backbone cyclization: stabilization of the alpha-conotoxin MII.

21 January 2018

1 reference

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Prolactin receptor antagonists that inhibit the growth of breast cancer cell lines

21 January 2018

1 reference

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A modification of receptor theory

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05567.X

Chemical synthesis and folding pathways of large cyclic polypeptides: studies of the cystine knot polypeptide kalata B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05567.X

An unusual structural motif of antimicrobial peptides containing end-to-end macrocycle and cystine-knot disulfides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05567.X

Structures of the agouti signaling protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05567.X

The cystine-knot growth-factor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05567.X

A fusion protein system for the recombinant production of short disulfide bond rich cystine knot peptides using barnase as a purification handle

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05567.X

c-mpl mutations are the cause of congenital amegakaryocytic thrombocytopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05567.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05567.X

10.1111/J.1742-4658.2006.05567.X

21 January 2018

Identifiers

DOI

1 reference

19 September 2017

1 reference