(Q40264901)

19 September 2017

A role for the G12 family of heterotrimeric G proteins in prostate cancer invasion (English)

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19 September 2017

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Patrick Kelly

1

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19 September 2017

Laura N Stemmle

2

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19 September 2017

John F Madden

3

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19 September 2017

Timothy A Fields

4

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19 September 2017

Yehia Daaka

5

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19 September 2017

Patrick J Casey

6

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19 September 2017

language of work or name

English

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publication date

20 June 2006

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Journal of Biological Chemistry

19 September 2017

8

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based on heuristic

inferred from page(s)

published in

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19 September 2017

281

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19 September 2017

26483-26490

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19 September 2017

36

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19 September 2017

Cancer statistics, 2006

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https://api.crossref.org/works/10.1074%2FJBC.M604376200

In vivo functions of heterotrimeric G-proteins: studies in Galpha-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

PAR1-mediated NFkappaB activation promotes survival of prostate cancer cells through a Bcl-xL-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Differential expression of thromboxane synthase in prostate carcinoma: role in tumor cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Lysophosphatidic acid stimulates PC-3 prostate cancer cell Matrigel invasion through activation of RhoA and NF-kappaB activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Signalling functions and biochemical properties of pertussis toxin-resistant G-proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Seven-transmembrane receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Expression cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

A mutant alpha subunit of G12 potentiates the eicosanoid pathway and is highly oncogenic in NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

21 January 2018

Transforming G proteins

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https://api.crossref.org/works/10.1074%2FJBC.M604376200

The Drosophila gastrulation gene concertina encodes a G alpha-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Essential roles of G{alpha}12/13 signaling in distinct cell behaviors driving zebrafish convergence and extension gastrulation movements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Essential role for Galpha13 in endothelial cells during embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Epithelial-mesenchymal transitions in tumour progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Molecular requirements for epithelial-mesenchymal transition during tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Using Drosophila melanogaster to map human cancer pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Selective uncoupling of G alpha 12 from Rho-mediated signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Immortalized and tumorigenic adult human prostatic epithelial cell lines: characteristics and applications. Part 3. Oncogenes, suppressor genes, and applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

The transforming activity of activated G alpha 12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

G13alpha-mediated PYK2 activation. PYK2 is a mediator of G13alpha -induced serum response element-dependent transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

The thrombin receptor, PAR-1, causes transformation by activation of Rho-mediated signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

21 January 2018

RHO-GTPases and cancer

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https://api.crossref.org/works/10.1074%2FJBC.M604376200

Galpha12 and Galpha13 negatively regulate the adhesive functions of cadherin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Interaction of Galpha 12 and Galpha 13 with the cytoplasmic domain of cadherin provides a mechanism for beta -catenin release

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Receptors coupled to heterotrimeric G proteins of the G12 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Mapping the Galpha13 binding interface of the rgRGS domain of p115RhoGEF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

The transcriptional coactivator FHL2 transmits Rho signals from the cell membrane into the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

RhoC GTPase is required for PC-3 prostate cancer cell invasion but not motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Increased expression of prostate-specific G-protein-coupled receptor in human prostate intraepithelial neoplasia and prostate cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Galpha12/13 is essential for directed cell migration and localized Rho-Dia1 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Rho-kinase inhibitor retards migration and in vivo dissemination of human prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Overexpression of RhoA-GTP induces activation of the Epidermal Growth Factor Receptor, dephosphorylation of focal adhesion kinase and increased motility in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Mitogen activated protein kinase pathway is involved in RhoC GTPase induced motility, invasion and angiogenesis in inflammatory breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

Dual roles of E-cadherin in prostate cancer invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604376200

21 January 2018

Identifiers

DOI

10.1074/JBC.M604376200

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19 September 2017

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