(Q40274520)

English

Potentiation of paclitaxel activity by the HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin in human ovarian carcinoma cell lines with high levels of activated AKT.

scientific article published on May 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

retracted paper

2 references

Dataset for "Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine"

Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine

Potentiation of paclitaxel activity by the HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin in human ovarian carcinoma cell lines with high levels of activated AKT. (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

ovarian carcinoma

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

7

object named as

Paul Workman

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

author name string

Nivedita Sain

1

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Bhavani Krishnan

2

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Michael G Ormerod

3

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Assunta De Rienzo

4

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Wai M Liu

5

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Stanley B Kaye

6

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Ann L Jackman

8

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

publication date

1 May 2006

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Molecular Cancer Therapeutics

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

1197-1208

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

The Hallmarks of Cancer

1 reference

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Translating basic cancer research into new cancer therapeutics

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Sequence-dependent enhancement of paclitaxel toxicity in non-small cell lung cancer by 17-allylamino 17-demethoxygeldanamycin

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alpha(v) integrins regulate cell proliferation through integrin-linked kinase (ILK) in ovarian cancer cells

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EGFR gene mutations: a call for global x global views of cancer

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Ovarian cancer: strategies for overcoming resistance to chemotherapy

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Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer

1 reference

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DT-Diaphorase expression and tumor cell sensitivity to 17-allylamino, 17-demethoxygeldanamycin, an inhibitor of heat shock protein 90

1 reference

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The role of genetic abnormalities of PTEN and the phosphatidylinositol 3-kinase pathway in breast and ovarian tumorigenesis, prognosis, and therapy

1 reference

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Gene expression profiling of human colon cancer cells following inhibition of signal transduction by 17-allylamino-17-demethoxygeldanamycin, an inhibitor of the hsp90 molecular chaperone.

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A study of some variables in a tetrazolium dye (MTT) based assay for cell growth and chemosensitivity

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Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study

1 reference

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Putting the rap on Akt.

1 reference

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Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

1 reference

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Clinical Development of 17-Allylamino, 17-Demethoxygeldanamycin

1 reference

30 December 2023

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The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors

1 reference

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STI571 (Gleevec) as a paradigm for cancer therapy

1 reference

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ERBB receptors and cancer: the complexity of targeted inhibitors

1 reference

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Ansamycin antibiotics inhibit Akt activation and cyclin D expression in breast cancer cells that overexpress HER2.

1 reference

30 December 2023

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Formation of 17-allylamino-demethoxygeldanamycin (17-AAG) hydroquinone by NAD(P)H:quinone oxidoreductase 1: role of 17-AAG hydroquinone in heat shock protein 90 inhibition

1 reference

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Phase I and pharmacologic study of 17-(allylamino)-17-demethoxygeldanamycin in adult patients with solid tumors.

1 reference

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Hsp90 as a therapeutic target in prostate cancer

1 reference

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HSP90 as a new therapeutic target for cancer therapy: the story unfolds

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AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth

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Who will benefit from treatment against EGFR?

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Combinatorial attack on multistep oncogenesis by inhibiting the Hsp90 molecular chaperone

1 reference

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Heat-shock protein 90 inhibitors as novel cancer chemotherapeutics - an update

1 reference

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PIK3CA is implicated as an oncogene in ovarian cancer.

1 reference

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Biological properties of ten human ovarian carcinoma cell lines: calibration in vitro against four platinum complexes

1 reference

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In vitro circumvention of cisplatin resistance by the novel sterically hindered platinum complex AMD473

1 reference

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The Stress Response: Implications for the Clinical Development of Hsp90 Inhibitors

1 reference

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Induction of apoptosis and stress response in ovarian carcinoma cell lines treated with ST1926, an atypical retinoid

1 reference

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

1 reference

30 December 2023

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Quantitative effects on c-Jun N-terminal protein kinase signaling determine synergistic interaction of cisplatin and 17-allylamino-17-demethoxygeldanamycin in colon cancer cell lines

1 reference

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The Hsp90 inhibitor geldanamycin selectively sensitizes Bcr-Abl-expressing leukemia cells to cytotoxic chemotherapy

1 reference

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Phase I pharmacokinetic and pharmacodynamic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies

1 reference

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Identifiers

10.1158/1535-7163.MCT-05-0445

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

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