(Q40276202)

English

Redirection of T cells by delivering a transgenic mouse-derived MDM2 tumor antigen-specific TCR and its humanized derivative is governed by the CD8 coreceptor and affects natural human TCR expression

scientific article published on January 2006

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1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Redirection of T cells by delivering a transgenic mouse-derived MDM2 tumor antigen-specific TCR and its humanized derivative is governed by the CD8 coreceptor and affects natural human TCR expression (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Christoph Huber

6

object named as

Christoph Huber

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

author name string

Ralf-Holger Voss

1

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Jürgen Kuball

2

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Renate Engel

3

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Philippe Guillaume

4

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Pedro Romero

5

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Matthias Theobald

7

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

publication date

1 January 2006

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Europe PubMed Central

PubMed publication ID

19 September 2017

Immunologic Research

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Europe PubMed Central

PubMed publication ID

19 September 2017

34

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Europe PubMed Central

PubMed publication ID

19 September 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

67-87

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Europe PubMed Central

PubMed publication ID

19 September 2017

TCRs with high affinity for foreign pMHC show self-reactivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High avidity CTLs for two self-antigens demonstrate superior in vitro and in vivo antitumor efficacy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amplification of a gene encoding a p53-associated protein in human sarcomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changing T cell specificity by retroviral T cell receptor display

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Location of the epitope for an anti-CD8alpha antibody 53.6.7 which enhances CD8alpha-MHC class I interaction indicates antibody stabilization of a higher affinity CD8 conformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Durable engraftment of major histocompatibility complex-incompatible cells after nonmyeloablative conditioning with fludarabine, low-dose total body irradiation, and posttransplantation cyclophosphamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TCR affinity and negative regulation limit autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient transfer of a tumor antigen-reactive TCR to human peripheral blood lymphocytes confers anti-tumor reactivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generating p53-specific cytotoxic T lymphocytes by recombinant adenoviral vector-based vaccination in mice, but not man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reprogramming of virus-specific T cells into leukemia-reactive T cells using T cell receptor gene transfer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: tumor-specific CTL are constitutively cross-armed in draining lymph nodes and transiently disseminate to mediate tumor regression following systemic CD40 activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the p53 protein by the MDM2 oncoprotein--thirty-eighth G.H.A. Clowes Memorial Award Lecture

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selecting T cell receptors with high affinity for self-MHC by decreasing the contribution of CD8.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterizing the Impact of CD8 Antibodies on Class I MHC Multimer Binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of unresponsiveness limits tumor protection by adoptively transferred MDM2-specific cytotoxic T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonmyeloablative immunosuppressive regimen prolongs In vivo persistence of gene-modified autologous T cells in a nonhuman primate model

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunotherapy through TCR gene transfer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-CD8 antibodies can inhibit or enhance peptide-MHC class I (pMHCI) multimer binding: this is paralleled by their effects on CTL activation and occurs in the absence of an interaction between pMHCI and CD8 on the cell surface

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Redirection of antileukemic reactivity of peripheral T lymphocytes using gene transfer of minor histocompatibility antigen HA-2-specific T-cell receptor complexes expressing a conserved alpha joining region

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cooperation of Human Tumor-Reactive CD4+ and CD8+ T Cells after Redirection of Their Specificity by a High-Affinity p53A2.1-Specific TCR

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A critical role of T cell antigen receptor-transduced MHC class I-restricted helper T cells in tumor protection

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacologically regulated Fas-mediated death of adoptively transferred T cells in a nonhuman primate model.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Partial tyrosinase-specific self tolerance by HLA-A*0201-restricted cytotoxic T lymphocytes in mice and man

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adoptive therapy with CD8(+) T cells: it may get by with a little help from its friends

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BCR/ABL activates mdm2 mRNA translation via the La antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary human lymphocytes transduced with NY-ESO-1 antigen-specific TCR genes recognize and kill diverse human tumor cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentiation of tumor eradication by adoptive immunotherapy with T-cell receptor gene-transduced T-helper type 1 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD8-independent tumor cell recognition is a property of the T cell receptor and not the T cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous generation of CD8+ and CD4+ melanoma-reactive T cells by retroviral-mediated transfer of a single T-cell receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progressive differentiation and selection of the fittest in the immune response

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Redirecting human CD4+ T lymphocytes to the MHC class I-restricted melanoma antigen MAGE-A1 by TCR alphabeta gene transfer requires CD8alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antimelanoma activity of CTL generated from peripheral blood mononuclear cells after stimulation with autologous dendritic cells pulsed with melanoma gp100 peptide G209-2M is correlated to TCR avidity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High efficiency TCR gene transfer into primary human lymphocytes affords avid recognition of melanoma tumor antigen glycoprotein 100 and does not alter the recognition of autologous melanoma antigens

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The CD8 isoform CD8alphaalpha is not a functional homologue of the TCR co-receptor CD8alphabeta

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Strategies for immunotherapy of cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha 3 domain mutants of peptide/MHC class I multimers allow the selective isolation of high avidity tumor-reactive CD8 T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor eradication by wild-type p53-specific cytotoxic T lymphocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4+ T cells are required for the maintenance, not programming, of memory CD8+ T cells after acute infection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The CD8beta ectodomain contributes to the augmented coreceptor function of CD8alphabeta heterodimers relative to CD8alphaalpha homodimers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tolerance to p53 by A2.1-restricted cytotoxic T lymphocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The organizing principle in the formation of the T cell receptor-CD3 complex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral CD4(+)CD8(+) T cells are differentiated effector memory cells with antiviral functions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lineage relationship and protective immunity of memory CD8 T cell subsets

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human CD8 co–receptor is strictly involved in MHC–peptide tetramer–TCR binding and T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16720899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1385/IR:34:1:67

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

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1 reference

https://api.fatcat.wiki/v0/release/ezcwfbyozfhmtht66sllegrgja

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

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