(Q40279655)

19 September 2017

title

Structural basis for degenerate recognition of natural HIV peptide variants by cytotoxic lymphocytes (English)

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19 September 2017

4

Bruce D Walker

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19 September 2017

author name string

Erik Martinez-Hackert

1

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19 September 2017

Nadia Anikeeva

2

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19 September 2017

Spyros A Kalams

3

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19 September 2017

Wayne A Hendrickson

5

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19 September 2017

Yuri Sykulev

6

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19 September 2017

language of work or name

English

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publication date

15 May 2006

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Journal of Biological Chemistry

19 September 2017

published in

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19 September 2017

volume

281

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19 September 2017

issue

29

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19 September 2017

page(s)

20205-20212

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Patterns of immunodominance in HIV-1-specific cytotoxic T lymphocyte responses in two human histocompatibility leukocyte antigens (HLA)-identical siblings with HLA-A*0201 are influenced by epitope mutation.

19 September 2017

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Determinant of HIV-1 mutational escape from cytotoxic T lymphocytes

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Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical

21 January 2018

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21 January 2018

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High-resolution structure of HLA-A*0201 in complex with a tumour-specific antigenic peptide encoded by the MAGE-A4 gene

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Use of non-crystallographic symmetry in protein structure refinement

21 January 2018

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The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2

21 January 2018

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Structure of the complex between human T-cell receptor, viral peptide and HLA-A2

21 January 2018

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21 January 2018

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Three-dimensional structure of a peptide extending from one end of a class I MHC binding site

21 January 2018

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Crystal structures of HLA-A*0201 complexed with antigenic peptides with either the amino- or carboxyl-terminal group substituted by a methyl group

21 January 2018

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Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids

21 January 2018

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Structural evidence of T cell xeno-reactivity in the absence of molecular mimicry

21 January 2018

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The structural basis for the increased immunogenicity of two HIV-reverse transcriptase peptide variant/class I major histocompatibility complexes

21 January 2018

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Poor binding of a HER-2/neu epitope (GP2) to HLA-A2.1 is due to a lack of interactions with the center of the peptide

21 January 2018

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The structure and stability of an HLA-A*0201/octameric tax peptide complex with an empty conserved peptide-N-terminal binding site

21 January 2018

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Crystal structures of two closely related but antigenically distinct HLA-A2/melanocyte-melanoma tumor-antigen peptide complexes

21 January 2018

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Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2

21 January 2018

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High affinity xenoreactive TCR:MHC interaction recruits CD8 in absence of binding to MHC.

21 January 2018

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Crystal structures of the trimeric human immunodeficiency virus type 1 matrix protein: implications for membrane association and assembly

21 January 2018

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21 January 2018

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Positive selection of CD8+ T cells induced by major histocompatibility complex binding peptides in fetal thymic organ culture

21 January 2018

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High frequency of cross-reactive cytotoxic T lymphocytes elicited during the virus-induced polyclonal cytotoxic T lymphocyte response

21 January 2018

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Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen

21 January 2018

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Thermodynamics of T cell receptor binding to peptide-MHC: evidence for a general mechanism of molecular scanning

21 January 2018

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Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation

21 January 2018

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21 January 2018

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T cell cross-reactivity and conformational changes during TCR engagement

21 January 2018

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The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation

21 January 2018

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High-affinity T helper epitope induces complementary helper and APC polarization, increased CTL, and protection against viral infection

21 January 2018

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Enhanced immunogenicity of HIV-1 vaccine construct by modification of the native peptide sequence

21 January 2018

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Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia

21 January 2018

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The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

21 January 2018

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Distinct molecular mechanisms account for the specificity of two different T-cell receptors

21 January 2018

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Peptide contributes to the specificity of positive selection of CD8+ T cells in the thymus

21 January 2018

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A very high level of crossreactivity is an essential feature of the T-cell receptor

21 January 2018

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TCR binding to peptide-MHC stabilizes a flexible recognition interface

21 January 2018

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Absence of Immunodominant Anti-Gag p17 (SL9) Responses among Gag CTL-Positive, HIV-Uninfected Vaccine Recipients Expressing the HLA-A*0201 Allele

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M601934200

1 reference

19 September 2017

1 reference