(Q40281556)

19 September 2017

Site-specific phosphorylation and caspase cleavage differentially impact tau-microtubule interactions and tau aggregation (English)

1 reference

19 September 2017

1 reference

Huiping Ding

1

1 reference

19 September 2017

Tori A Matthews

series ordinal

2

1 reference

19 September 2017

Gail V W Johnson

series ordinal

3

1 reference

19 September 2017

language of work or name

English

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publication date

10 May 2006

1 reference

Journal of Biological Chemistry

19 September 2017

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19 September 2017

281

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19 September 2017

28

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19 September 2017

19107-19114

1 reference

Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease

19 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Memory and mental status correlates of modified Braak staging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Tau is essential to beta -amyloid-induced neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Tau suppression in a neurodegenerative mouse model improves memory function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Retarded axonal transport of R406W mutant tau in transgenic mice with a neurodegenerative tauopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

MAPK recruitment by beta-amyloid in organotypic hippocampal slice cultures depends on physical state and exposure time

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Structural and functional implications of tau hyperphosphorylation: information from phosphorylation-mimicking mutated tau proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

beta-Amyloid induces paired helical filament-like tau filaments in tissue culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

The neuronal microtubule-associated protein tau is a substrate for caspase-3 and an effector of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Proapoptotic effects of tau cleavage product generated by caspase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Glycogen synthase kinase 3 beta induces caspase-cleaved tau aggregation in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Nonsaturable binding indicates clustering of tau on the microtubule surface in a paired helical filament-like conformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Glycogen synthase kinase 3beta phosphorylates tau at both primed and unprimed sites. Differential impact on microtubule binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Unique Alzheimer's disease paired helical filament specific epitopes involve double phosphorylation at specific sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Casein kinase 1 delta phosphorylates tau and disrupts its binding to microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

A protein factor essential for microtubule assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Tau assembly in inducible transfectants expressing wild-type or FTDP-17 tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Phosphorylation of tau at both Thr 231 and Ser 262 is required for maximal inhibition of its binding to microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Modeling tau polymerization in vitro: a review and synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

Microtubule-dependent oligomerization of tau. Implications for physiological tau function and tauopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511697200

21 January 2018

Identifiers

DOI

10.1074/JBC.M511697200

1 reference

19 September 2017

1 reference