(Q40290179)

19 September 2017

title

Jab1 induces the cytoplasmic localization and degradation of p53 in coordination with Hdm2. (English)

1 reference

19 September 2017

Wonkyung Oh

1

1 reference

19 September 2017

Eun-Woo Lee

2

1 reference

19 September 2017

Young Hoon Sung

3

1 reference

19 September 2017

Mi-Ran Yang

4

1 reference

19 September 2017

Jaewang Ghim

5

1 reference

19 September 2017

Han-Woong Lee

6

1 reference

19 September 2017

Jaewhan Song

7

1 reference

19 September 2017

language of work or name

English

0 references

publication date

19 April 2006

1 reference

Journal of Biological Chemistry

19 September 2017

number of pages

9

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based on heuristic

inferred from page(s)

published in

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19 September 2017

volume

281

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19 September 2017

issue

25

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19 September 2017

page(s)

17457-17465

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Cancer. p53, guardian of the genome

19 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601857200

p53, the cellular gatekeeper for growth and division

21 January 2018

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Live or let die: the cell's response to p53

21 January 2018

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The importance of p53 location: nuclear or cytoplasmic zip code?

21 January 2018

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Regulating the p53 system through ubiquitination

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M601857200

Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex

21 January 2018

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Polyubiquitination of p53 by a ubiquitin ligase activity of p300.

21 January 2018

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Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601857200

The ubiquitin ligase COP1 is a critical negative regulator of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601857200

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601857200

Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601857200

An intact HDM2 RING-finger domain is required for nuclear exclusion of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601857200

The MDM2 RING-finger domain is required to promote p53 nuclear export

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601857200

Mono- versus polyubiquitination: differential control of p53 fate by Mdm2.

21 January 2018

1 reference

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A new group of conserved coactivators that increase the specificity of AP-1 transcription factors

21 January 2018

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Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601857200

The COP9 Signalosome Promotes Degradation of Cyclin E during Early Drosophila Oogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601857200

Jab1/CSN5, a component of the COP9 signalosome, regulates transforming growth factor beta signaling by binding to Smad7 and promoting its degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601857200

Jab1 antagonizes TGF-beta signaling by inducing Smad4 degradation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M601857200

CSN5/Jab1 is involved in ligand-dependent degradation of estrogen receptor {alpha} by the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601857200

Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1.

21 January 2018

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COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601857200

Multiple functions of Jab1 are required for early embryonic development and growth potential in mice

21 January 2018

1 reference

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Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601857200

MDM2 can promote the ubiquitination, nuclear export, and degradation of p53 in the absence of direct binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601857200

Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity

21 January 2018

1 reference

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Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 January 2018

1 reference

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A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking

21 January 2018

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Identification of a functional nuclear export sequence in BRCA1.

21 January 2018

1 reference

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Regulation of the p53 tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601857200

Nucleolar Arf sequesters Mdm2 and activates p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601857200

Cellular stress and DNA damage invoke temporally distinct Mdm2, p53 and PML complexes and damage-specific nuclear relocalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601857200

PML regulates p53 stability by sequestering Mdm2 to the nucleolus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601857200

The cytoplasmic shuttling and subsequent degradation of p27Kip1 mediated by Jab1/CSN5 and the COP9 signalosome complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601857200

Skp2 and Jab1 expression are associated with inverse expression of p27(KIP1) and poor prognosis in oral squamous cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601857200

Immunohistochemical study of Skp2 and Jab1, two key molecules in the degradation of P27, in lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601857200

21 January 2018

Identifiers

DOI

10.1074/JBC.M601857200

1 reference

19 September 2017

1 reference