(Q40296129)

English

Intrathecal infusion of a Ca(2+)-permeable AMPA channel blocker slows loss of both motor neurons and of the astrocyte glutamate transporter, GLT-1 in a mutant SOD1 rat model of ALS.

scientific article published on 24 July 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

Intrathecal infusion of a Ca(2+)-permeable AMPA channel blocker slows loss of both motor neurons and of the astrocyte glutamate transporter, GLT-1 in a mutant SOD1 rat model of ALS. (English)

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

0 references

amyotrophic lateral sclerosis

1 reference

based on heuristic

inferred from title

author name string

Hong Z Yin

1

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

Darryl T Tang

2

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

John H Weiss

3

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

language of work or name

0 references

publication date

24 July 2007

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

Experimental Neurology

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

207

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

2

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

177-185

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

22 September 2017

Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

22 September 2017

Onset and progression in inherited ALS determined by motor neurons and microglia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

22 September 2017

Late-onset motoneuron disease caused by a functionally modified AMPA receptor subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

22 September 2017

Excitotoxic and oxidative cross-talk between motor neurons and glia in ALS pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

22 September 2017

Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

22 September 2017

Ca(2+)-permeable AMPA receptors and selective vulnerability of motor neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

22 September 2017

Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

22 September 2017

Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

22 September 2017

Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

22 September 2017

AMPA exposures induce mitochondrial Ca(2+) overload and ROS generation in spinal motor neurons in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

15 June 2018

Neuroprotective strategies in a model of chronic glutamate-mediated motor neuron toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

15 June 2018

In vitro kainate injury to large, SMI-32(+) spinal neurons is Ca2+ dependent.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

15 June 2018

Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

15 June 2018

GluR2 deficiency accelerates motor neuron degeneration in a mouse model of amyotrophic lateral sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

20 August 2018

Activated microglia initiate motor neuron injury by a nitric oxide and glutamate-mediated mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

20 August 2018

Viral-induced spinal motor neuron death is non-cell-autonomous and involves glutamate excitotoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

20 August 2018

Calcium-permeable AMPA receptors promote misfolding of mutant SOD1 protein and development of amyotrophic lateral sclerosis in a transgenic mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

20 August 2018

Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

20 August 2018

Increased expression of the glial glutamate transporter EAAT2 modulates excitotoxicity and delays the onset but not the outcome of ALS in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

20 August 2018

A double-lumen intrathecal catheter for studies of modulation of spinal opiate tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

20 August 2018

Disruption of glial glutamate transport by reactive oxygen species produced in motor neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

20 August 2018

Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

20 August 2018

Elevated cortical extracellular fluid glutamate in transgenic mice expressing human mutant (G93A) Cu/Zn superoxide dismutase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

20 August 2018

Endogenous calcium buffering in motoneurones of the nucleus hypoglossus from mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

20 August 2018

Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

20 August 2018

Motor neurons are selectively vulnerable to AMPA/kainate receptor-mediated injury in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083564

20 August 2018

Kainic acid induces early and delayed degenerative neuronal changes in rat spinal cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/17719032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17719032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of the astrocyte glutamate transporter GLT1 modifies disease in SOD1(G93A) mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17719032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMPA receptor calcium permeability, GluR2 expression, and selective motoneuron vulnerability

1 reference

https://pubmed.ncbi.nlm.nih.gov/17719032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/17719032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.EXPNEUROL.2007.07.011

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

release_e5hv4zwucncrzps2uk3hspg4fm

1 reference

https://api.fatcat.wiki/v0/release/e5hv4zwucncrzps2uk3hspg4fm

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

ResearchGate publication ID

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