(Q40306798)

English

The conserved glutamate (Glu136) in transmembrane domain 2 of the serotonin transporter is required for the conformational switch in the transport cycle.

scientific article published on 9 March 2006

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16527819%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

The conserved glutamate (Glu136) in transmembrane domain 2 of the serotonin transporter is required for the conformational switch in the transport cycle (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16527819%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

transmembrane transport

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transmembrane protein

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4

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17 January 2020

Michael Freissmuth

3

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17 January 2020

author name string

Vladimir M Korkhov

1

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17 January 2020

Marion Holy

2

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17 January 2020

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publication date

9 March 2006

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17 January 2020

number of pages

10

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Journal of Biological Chemistry

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17 January 2020

281

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17 January 2020

19

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17 January 2020

13439-13448

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17 January 2020

From synapse to vesicle: the reuptake and storage of biogenic amine neurotransmitters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Excitatory amino acid transporters: a family in flux

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

The transporter classification (TC) system, 2002

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Plasma membrane monoamine transporters: structure, regulation and function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Oligomer formation by Na+-Cl--coupled neurotransmitter transporters.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Mutations within an intramembrane leucine heptad repeat disrupt oligomer formation of the rat GABA transporter 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Oligomerization and trafficking of the human dopamine transporter. Mutational analysis identifies critical domains important for the functional expression of the transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Oligomerization of Dopamine Transporters Visualized in Living Cells by Fluorescence Resonance Energy Transfer Microscopy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Two discontinuous segments in the carboxyl terminus are required for membrane targeting of the rat gamma-aminobutyric acid transporter-1 (GAT1)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Oligomerization of the {gamma}-aminobutyric acid transporter-1 is driven by an interplay of polar and hydrophobic interactions in transmembrane helix II

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Identification of an additional interaction domain in transmembrane domains 11 and 12 that supports oligomer formation in the human serotonin transporter.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Sodium-dependent neurotransmitter transporters: oligomerization as a determinant of transporter function and trafficking

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Functional significance of a highly conserved glutamate residue of the human noradrenaline transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Oligomerization of the human serotonin transporter and of the rat GABA transporter 1 visualized by fluorescence resonance energy transfer microscopy in living cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Pharmacochaperones post-translationally enhance cell surface expression by increasing conformational stability of wild-type and mutant vasopressin V2 receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Characterization of a functional bacterial homologue of sodium-dependent neurotransmitter transporters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Simple Allosteric Model for Membrane Pumps

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Structure and mechanism of the lactose permease of Escherichia coli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Ligand binding to the serotonin transporter: equilibria, kinetics, and ion dependence.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Generation of an activating Zn(2+) switch in the dopamine transporter: mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Ionic currents in the human serotonin transporter reveal inconsistencies in the alternating access hypothesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Flux coupling in the human serotonin transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Secondary active transport mediated by a prokaryotic homologue of ClC Cl- channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Cloning, expression, and localization of a chloride-facilitated, cocaine-sensitive serotonin transporter from Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Ionic interactions in the Drosophila serotonin transporter identify it as a serotonin channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

The role of conserved tryptophan and acidic residues in the human dopamine transporter as characterized by site-directed mutagenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

A pincer-like configuration of TM2 in the human dopamine transporter is responsible for indirect effects on cocaine binding.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Analysis of transmembrane domain 2 of rat serotonin transporter by cysteine scanning mutagenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511382200

21 January 2018

Identifiers

10.1074/JBC.M511382200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16527819%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16527819%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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