(Q40308333)

19 September 2017

title

Mutations of the PTPN11 and RAS genes in rhabdomyosarcoma and pediatric hematological malignancies (English)

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19 September 2017

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Yuyan Chen

1

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19 September 2017

Junko Takita

2

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19 September 2017

Mitsuteru Hiwatari

3

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19 September 2017

Takashi Igarashi

4

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19 September 2017

Ryoji Hanada

5

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19 September 2017

Akira Kikuchi

6

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19 September 2017

Teruaki Hongo

7

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19 September 2017

Tomohiko Taki

8

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19 September 2017

Mizuho Ogasawara

9

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19 September 2017

Akira Shimada

10

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19 September 2017

Yasuhide Hayashi

11

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19 September 2017

publication date

1 June 2006

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Genes, Chromosomes and Cancer

19 September 2017

published in

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19 September 2017

volume

45

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19 September 2017

issue

6

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19 September 2017

page(s)

583-591

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The ras gene family and human carcinogenesis

19 September 2017

cites work

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Biased suppression of hematopoiesis and multiple developmental defects in chimeric mice containing Shp-2 mutant cells

21 January 2018

1 reference

Neurofibromatosis--Noonan's syndrome with associated rhabdomyosarcoma of the urinary bladder in an infant: case report

21 January 2018

1 reference

7 January 2021

Germline mutations in HRAS proto-oncogene cause Costello syndrome

1 reference

7 January 2021

Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia

1 reference

7 January 2021

Neuroblastoma: biological insights into a clinical enigma

1 reference

7 January 2021

N-ras gene activation in the RD human rhabdomyosarcoma cell line.

1 reference

7 January 2021

Noonan Syndrome and Neuroblastoma

1 reference

7 January 2021

Noonan syndrome-associated SHP2/PTPN11 mutants cause EGF-dependent prolonged GAB1 binding and sustained ERK2/MAPK1 activation

1 reference

7 January 2021

Infant cancer in the U.S.: histology-specific incidence and trends, 1973 to 1992.

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7 January 2021

Crystal structure of the tyrosine phosphatase SHP-2

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7 January 2021

A case of Noonan's syndrome with possible associated neuroblastoma

1 reference

7 January 2021

Orbital rhabdomyosarcoma in Noonan syndrome

1 reference

7 January 2021

Alterations of the p53, p21, p16, p15 and RAS genes in childhood T-cell acute lymphoblastic leukemia

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7 January 2021

Diverse biochemical properties of Shp2 mutants. Implications for disease phenotypes

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7 January 2021

Vaginal rhabdomyosarcoma in a patient with Noonan syndrome

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7 January 2021

The mutational spectrum of PTPN11 in juvenile myelomonocytic leukemia and Noonan syndrome/myeloproliferative disease

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7 January 2021

PTPN11 mutations in pediatric patients with acute myeloid leukemia: results from the Children's Cancer Group

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7 January 2021

Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis

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7 January 2021

Noonan syndrome associated with neuroblastoma: a case report.

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7 January 2021

Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations.

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7 January 2021

The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling

1 reference

7 January 2021

Functional analysis of PTPN11/SHP-2 mutants identified in Noonan syndrome and childhood leukemia

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7 January 2021

Activated mutants of SHP-2 preferentially induce elongation of Xenopus animal caps

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7 January 2021

Requirement of Shp-2 tyrosine phosphatase in lymphoid and hematopoietic cell development

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7 January 2021

The SH2 tyrosine phosphatase shp2 is required for mammalian limb development.

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7 January 2021

Functional analysis of leukemia-associated PTPN11 mutations in primary hematopoietic cells

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7 January 2021

Mutations of the RAS genes in childhood acute myeloid leukemia, myelodysplastic syndrome and juvenile chronic myelocytic leukemia.

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7 January 2021

t(10;11)-acute leukemias with MLL-AF10 and MLL-ABI1 chimeric transcripts: specific expression patterns of ABI1 gene in leukemia and solid tumor cell lines

1 reference

7 January 2021

The chromosome translocation t(7;11)(p15;p15) in acute myeloid leukemia results in fusion of the NUP98 gene with a HOXA cluster gene, HOXA13, but not HOXA9

1 reference

7 January 2021

FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy

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7 January 2021

Gene expression profiling and identification of novel prognostic marker genes in neuroblastoma

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7 January 2021

Allelic imbalance on chromosome 2q and alterations of the caspase 8 gene in neuroblastoma

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7 January 2021

Paternal germline origin and sex-ratio distortion in transmission of PTPN11 mutations in Noonan syndrome

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7 January 2021

Germ-line and somatic PTPN11 mutations in human disease

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7 January 2021

PTPN11 mutations in Noonan syndrome: molecular spectrum, genotype-phenotype correlation, and phenotypic heterogeneity

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7 January 2021

Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia

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7 January 2021

Diversity and functional consequences of germline and somatic PTPN11 mutations in human disease

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7 January 2021

Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome

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7 January 2021

Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia

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7 January 2021

Aberrations of the hSNF5/INI1 gene are restricted to malignant rhabdoid tumors or atypical teratoid/rhabdoid tumors in pediatric solid tumors

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7 January 2021

Genomic structure and mutational analysis of the human KIF1B gene which is homozygously deleted in neuroblastoma at chromosome 1p36.2

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7 January 2021

Identifiers

DOI

10.1002/GCC.20322

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19 September 2017

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