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ASK-1 (apoptosis signal-regulating kinase 1) is a direct E2F target gene.
scientific article published on June 2006
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
1482812
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16512785%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
title
ASK-1 (apoptosis signal-regulating kinase 1) is a direct E2F target gene
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
1482812
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16512785%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
author
Didier Monté
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
1482812
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16512785%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
author name string
Zoulika Kherrouche
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
1482812
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16512785%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
Alexandre Blais
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
1482812
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16512785%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
Elisabeth Ferreira
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
1482812
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16512785%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
Yvan De Launoit
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
1482812
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16512785%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
language of work or name
English
0 references
publication date
1 June 2006
1 reference
stated in
Europe PubMed Central
PMC publication ID
1482812
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16512785%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
published in
Biochemical Journal
1 reference
stated in
Europe PubMed Central
PMC publication ID
1482812
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16512785%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
volume
396
1 reference
stated in
Europe PubMed Central
PMC publication ID
1482812
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16512785%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
issue
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
1482812
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16512785%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
page(s)
547-556
1 reference
stated in
Europe PubMed Central
PMC publication ID
1482812
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16512785%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
cites work
The E2F transcriptional network: old acquaintances with new faces
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
Gene expression profiling of E2F-1-induced apoptosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
Hitting their targets: an emerging picture of E2F and cell cycle control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
The NRF-1/alpha-PAL transcription factor regulates human E2F6 promoter activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
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22 September 2017
Direct binding of apoptosis signal-regulating kinase 1 to retinoblastoma protein: novel links between apoptotic signaling and cell cycle machinery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
ASK1 (MAP3K5) as a potential therapeutic target in malignant fibrous histiocytomas with 12q14-q15 and 6q23 amplifications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
ASK1 inhibits astroglial development via p38 mitogen-activated protein kinase and promotes neuronal differentiation in adult hippocampus-derived progenitor cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
Roles of MAPKKK ASK1 in stress-induced cell death.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
E2F1 pathways to apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
Regulation of the human cyclin-dependent kinase inhibitor p18INK4c by the transcription factors E2F1 and Sp1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
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22 September 2017
Gene expression changes in response to E2F1 activation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
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22 September 2017
Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
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22 September 2017
E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
Expression of transcription factor E2F1 induces quiescent cells to enter S phase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
Heterodimerization of the transcription factors E2F-1 and DP-1 is required for binding to the adenovirus E4 (ORF6/7) protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
Identifying differences in mRNA expression by representational difference analysis of cDNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
In vivo association of E2F and DP family proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
Cell cycle regulation of the cyclin A gene promoter is mediated by a variant E2F site
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
Role of an adenovirus E2 promoter binding factor in E1A-mediated coordinate gene control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
22 September 2017
E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
25 September 2017
Promoter interaction of the E1A-inducible factor E2F and its potential role in the formation of a multi-component complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
25 September 2017
Reduction of total E2F/DP activity induces senescence-like cell cycle arrest in cancer cells lacking functional pRB and p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
15 June 2018
E2F1 is crucial for E2F-dependent apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
20 August 2018
Human E2F6 is alternatively spliced to generate multiple protein isoforms.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
20 August 2018
Stable suppression of tumorigenicity by virus-mediated RNA interference
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
20 August 2018
Activation and autophosphorylation of apoptosis signal-regulating kinase 1 (ASK1) following cerebral ischemia in rat hippocampus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
20 August 2018
Computer-assisted identification of cell cycle-related genes: new targets for E2F transcription factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
4 November 2018
ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482812
retrieved
4 November 2018
Tumor induction and tissue atrophy in mice lacking E2F-1
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16512785
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
E2F-1 functions in mice to promote apoptosis and suppress proliferation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16512785
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1042/BJ20051981
1 reference
stated in
Europe PubMed Central
PMC publication ID
1482812
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16512785%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
PMC publication ID
1482812
1 reference
stated in
Europe PubMed Central
PMC publication ID
1482812
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16512785%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
PubMed publication ID
16512785
1 reference
stated in
Europe PubMed Central
PMC publication ID
1482812
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16512785%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
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