(Q34922303)

5 August 2017

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title

E2F1 pathways to apoptosis (English)

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5 August 2017

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Doron Ginsberg

1

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PubMed ID

12354623

5 August 2017

language of work or name

English

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publication date

1 October 2002

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5 August 2017

4

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based on heuristic

inferred from page(s)

published in

FEBS Letters

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5 August 2017

529

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5 August 2017

122-125

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5 August 2017

1

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The regulation of E2F by pRB-family proteins

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

The Rb/E2F pathway: expanding roles and emerging paradigms

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

The retinoblastoma protein and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

Sibling rivalry in the E2F family

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

Distinct roles for E2F proteins in cell growth control and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

21 January 2018

E2F-1 induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

p53 and E2F-1 cooperate to mediate apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

E2F-1 blocks terminal differentiation and causes proliferation in transgenic megakaryocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

E2F-1-induced p53-independent apoptosis in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

Induction of DNA synthesis and apoptosis are separable functions of E2F-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

p14ARF links the tumour suppressors RB and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

Nucleolar Arf sequesters Mdm2 and activates p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

ARF differentially modulates apoptosis induced by E2F1 and Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

p19(ARF) is dispensable for oncogenic stress-induced p53-mediated apoptosis and tumor suppression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

p14(ARF) regulates E2F activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

p19ARF targets certain E2F species for degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

E2F1 induces phosphorylation of p53 that is coincident with p53 accumulation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

Novel function of the cyclin A binding site of E2F in regulating p53-induced apoptosis in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

Role for the p53 homologue p73 in E2F-1-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

Role of the p53-homologue p73 in E2F1-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

A common E2F-1 and p73 pathway mediates cell death induced by TCR activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

Apaf-1 is a transcriptional target for E2F and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

Identification of novel E2F1-regulated genes by microarray

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

E2Fs up-regulate expression of genes involved in DNA replication, DNA repair and mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

Gene expression changes in response to E2F1 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

E2F-1 potentiates cell death by blocking antiapoptotic signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

NF-kappaB at the crossroads of life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

E2F-1 cooperates with topoisomerase II inhibition and DNA damage to selectively augment p53-independent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

Increased levels of E2F-1-dependent DNA binding activity after UV- or gamma-irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

E2F-1 functions in mice to promote apoptosis and suppress proliferation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

Myc requires distinct E2F activities to induce S phase and apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

ARF is not required for apoptosis in Rb mutant mouse embryos

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

Stress signals induce transcriptionally inactive E2F-1 independently of p53 and Rb

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903270-2

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0014-5793(02)03270-2

1 reference

5 August 2017

1 reference

PubMed ID

12354623