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p19ARF targets certain E2F species for degradation.
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Europe PubMed Central
PMCID
31856
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11274364%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
title
p19ARF targets certain E2F species for degradation
(English)
1 reference
stated in
Europe PubMed Central
PMCID
31856
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11274364%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
author
Norman Sharpless
series ordinal
4
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Europe PubMed Central
PMCID
31856
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11274364%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
Fabio Martelli
series ordinal
1
1 reference
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PMCID
31856
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11274364%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
author name string
T Hamilton
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2
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31856
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11274364%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
D P Silver
series ordinal
3
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PMCID
31856
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11274364%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
N Bardeesy
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5
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PMCID
31856
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11274364%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
M Rokas
series ordinal
6
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PMCID
31856
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11274364%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
R A DePinho
series ordinal
7
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31856
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5 November 2019
D M Livingston
series ordinal
8
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31856
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5 November 2019
S R Grossman
series ordinal
9
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PMCID
31856
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11274364%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
language of work or name
English
0 references
publication date
27 March 2001
1 reference
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Europe PubMed Central
PMCID
31856
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5 November 2019
published in
Proceedings of the National Academy of Sciences of the United States of America
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Europe PubMed Central
PMCID
31856
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11274364%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
volume
98
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stated in
Europe PubMed Central
PMCID
31856
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11274364%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
page(s)
4455-4460
1 reference
stated in
Europe PubMed Central
PMCID
31856
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11274364%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
issue
8
1 reference
stated in
Europe PubMed Central
PMCID
31856
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11274364%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
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An N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivo
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INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.
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Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53
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P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2
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E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription
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ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
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The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
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12 July 2018
Binding and modulation of p53 by p300/CBP coactivators
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12 July 2018
Regulation of E2F through ubiquitin-proteasome-dependent degradation: stabilization by the pRB tumor suppressor protein
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31856
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12 July 2018
Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31856
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12 July 2018
The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31856
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12 July 2018
A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes
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PubMed Central
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12 July 2018
Nuclear localization of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members
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12 July 2018
Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31856
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12 July 2018
MyoD induces retinoblastoma gene expression during myogenic differentiation.
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12 July 2018
Phosphorylation of a specific cdk site in E2F-1 affects its electrophoretic mobility and promotes pRB-binding in vitro
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12 July 2018
The high levels of p53 present in adenovirus early region 1-transformed human cells do not cause up-regulation of MDM2 expression.
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PubMed Central
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12 July 2018
Distinct modulation of p53 activity in transcription and cell-cycle regulation by the large (54 kDa) and small (21 kDa) adenovirus E1B proteins
1 reference
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PubMed Central
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12 July 2018
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
1 reference
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PubMed Central
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12 July 2018
Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31856
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12 July 2018
Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: a comparison of the "hot spot" mutant phenotypes
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31856
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12 July 2018
Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31856
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12 July 2018
Tumor surveillance via the ARF-p53 pathway.
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31856
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26 September 2018
Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11274364
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11274364
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
p16INK4A and p19ARF act in overlapping pathways in cellular immortalization
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11274364
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.081061398
1 reference
stated in
Europe PubMed Central
PMCID
31856
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11274364%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
ADS bibcode
2001PNAS...98.4455M
0 references
PMCID
31856
1 reference
stated in
Europe PubMed Central
PMCID
31856
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11274364%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
PubMed ID
11274364
1 reference
stated in
Europe PubMed Central
PMCID
31856
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11274364%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
ResearchGate publication ID
12059496
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