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English
Stress signals induce transcriptionally inactive E2F-1 independently of p53 and Rb
scientific article published on 01 May 2000
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10828878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10828878%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
title
Stress signals induce transcriptionally inactive E2F-1 independently of p53 and Rb
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10828878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10828878%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
author name string
O'Connor DJ
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10828878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10828878%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
Lu X
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10828878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10828878%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
language of work or name
English
0 references
publication date
1 May 2000
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10828878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10828878%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
published in
Oncogene
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10828878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10828878%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
volume
19
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10828878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10828878%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
issue
20
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10828878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10828878%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
page(s)
2369-2376
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10828878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10828878%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
exact match
https://scigraph.springernature.com/pub.10.1038/sj.onc.1203540
0 references
cites work
The retinoblastoma gene product is reversibly dephosphorylated and bound in the nucleus in S and G2 phases during hypoxic stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The E2F transcription factor is a cellular target for the RB protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct roles for E2F proteins in cell growth control and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-1 functions in mice to promote apoptosis and suppress proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of apoptosis by the retinoblastoma gene product.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-5, a new E2F family member that interacts with p130 in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased levels of E2F-1-dependent DNA binding activity after UV- or gamma-irradiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-1-induced p53-independent apoptosis in transgenic mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic capacity of the E2F1 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of transcription factor E2F1 induces quiescent cells to enter S phase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53: puzzle and paradigm
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia-induced pRB hypophosphorylation results from downregulation of CDK and upregulation of PP1 activities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DRTF1/E2F: an expanding family of heterodimeric transcription factors implicated in cell-cycle control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DP and E2F proteins: coordinating transcription with cell cycle progression.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-1 cooperates with topoisomerase II inhibition and DNA damage to selectively augment p53-independent apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of DNA synthesis and apoptosis are separable functions of E2F-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-6, a member of the E2F family that can behave as a transcriptional repressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Residues phosphorylated by TFIIH are required for E2F-1 degradation during S-phase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 and E2F-1 cooperate to mediate apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor induction and tissue atrophy in mice lacking E2F-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203540
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1203540
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10828878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10828878%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
Dimensions Publication ID
1041658848
0 references
PubMed publication ID
10828878
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10828878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10828878%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
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