(Q40318346)

19 September 2017

title

Individual Timp deficiencies differentially impact pro-MMP-2 activation (English)

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19 September 2017

8

Eero Vuorio

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19 September 2017

3

Ilpo Koskivirta

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19 September 2017

Jane L English

1

1 reference

19 September 2017

Zamaneh Kassiri

2

1 reference

19 September 2017

Susan J Atkinson

4

1 reference

19 September 2017

Marco Di Grappa

5

1 reference

19 September 2017

Paul D Soloway

6

1 reference

19 September 2017

Hideaki Nagase

7

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19 September 2017

Gillian Murphy

9

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19 September 2017

Rama Khokha

10

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19 September 2017

language of work or name

English

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publication date

9 February 2006

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Journal of Biological Chemistry

19 September 2017

published in

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19 September 2017

volume

281

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19 September 2017

issue

15

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19 September 2017

page(s)

10337-10346

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Membrane-type 1 matrix metalloproteinase: a key enzyme for tumor invasion

19 September 2017

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Roles of membrane-type matrix metalloproteinase-1 in tumor invasion and metastasis

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Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion

21 January 2018

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Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration

21 January 2018

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CD44 directs membrane-type 1 matrix metalloproteinase to lamellipodia by associating with its hemopexin-like domain.

21 January 2018

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Expression of integrin alpha(v)beta(3) correlates with activation of membrane-type matrix metalloproteinase-1 (MT1-MMP) and matrix metalloproteinase-2 (MMP-2) in human melanoma cells in vitro and in vivo

21 January 2018

1 reference

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ECM regulates MT1-MMP localization with beta1 or alphavbeta3 integrins at distinct cell compartments modulating its internalization and activity on human endothelial cells

21 January 2018

1 reference

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Matrix metalloproteinases and tumor invasion: from correlation and causality to the clinic

21 January 2018

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Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.

21 January 2018

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Matrix-directed regulation of pericellular proteolysis and tumor progression

21 January 2018

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Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease

21 January 2018

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Intermolecular autolytic cleavage can contribute to the activation of progelatinase A by cell membranes

21 January 2018

1 reference

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Membrane-type-2 matrix metalloproteinase can initiate the processing of progelatinase A and is regulated by the tissue inhibitors of metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Identification of soluble type of membrane-type matrix metalloproteinase-3 formed by alternatively spliced mRNA

21 January 2018

1 reference

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Identification and characterization of the fifth membrane-type matrix metalloproteinase MT5-MMP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Control of type IV collagenase activity by components of the urokinase-plasmin system: a regulatory mechanism with cell-bound reactants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Cellular activation of MMP-2 (gelatinase A) by MT2-MMP occurs via a TIMP-2-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Differential inhibition of membrane type 3 (MT3)-matrix metalloproteinase (MMP) and MT1-MMP by tissue inhibitor of metalloproteinase (TIMP)-2 and TIMP-3 rgulates pro-MMP-2 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Activation of a recombinant membrane type 1-matrix metalloproteinase (MT1-MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

The TIMP2 membrane type 1 metalloproteinase "receptor" regulates the concentration and efficient activation of progelatinase A. A kinetic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Analysis of tissue inhibitor of metalloproteinases-2 effect on pro-matrix metalloproteinase-2 activation by membrane-type 1 matrix metalloproteinase using baculovirus/insect-cell expression system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

TIMP-2 is required for efficient activation of proMMP-2 in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Inactivating mutation of the mouse tissue inhibitor of metalloproteinases-2(Timp-2) gene alters proMMP-2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Selective involvement of TIMP-2 in the second activational cleavage of pro-MMP-2: refinement of the pro-MMP-2 activation mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation. Regulation by TIMP-2 and TIMP-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

The activity of the tissue inhibitors of metalloproteinases is regulated by C-terminal domain interactions: a kinetic analysis of the inhibition of gelatinase A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Unveiling the surface epitopes that render tissue inhibitor of metalloproteinase-1 inactive against membrane type 1-matrix metalloproteinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Molecular cloning and characterization of human tissue inhibitor of metalloproteinase 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Murine tissue inhibitor of metalloproteinases-4 (Timp-4): cDNA isolation and expression in adult mouse tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Specific, high affinity binding of tissue inhibitor of metalloproteinases-4 (TIMP-4) to the COOH-terminal hemopexin-like domain of human gelatinase A. TIMP-4 binds progelatinase A and the COOH-terminal domain in a similar manner to TIMP-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Analysis of lapine cartilage matrix after radiosynovectomy with holmium-166 ferric hydroxide macroaggregate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Accelerated apoptosis in the Timp-3-deficient mammary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Divergent effects of tissue inhibitor of metalloproteinase-1, -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro. TIMP-3 promotes apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

E. coli expression of TIMP-4 and comparative kinetic studies with TIMP-1 and TIMP-2: insights into the interactions of TIMPs and matrix metalloproteinase 2 (gelatinase A)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Cellular activation of mesangial gelatinase A by cytochalasin D is accompanied by enhanced mRNA expression of both gelatinase A and its membrane-associated gelatinase A activator (MT-MMP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Isolation of a mouse MT2-MMP gene from a lung cDNA library and identification of its product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

TIMP-2 (tissue inhibitor of metalloproteinase-2) regulates MMP-2 (matrix metalloproteinase-2) activity in the extracellular environment after pro-MMP-2 activation by MT1 (membrane type 1)-MMP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Membrane type I-matrix metalloproteinase (MT1-MMP) is internalised by two different pathways and is recycled to the cell surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Cellular cholesterol regulates MT1 MMP dependent activation of MMP 2 via MEK-1 in HT1080 fibrosarcoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Differential roles of TIMP-4 and TIMP-2 in pro-MMP-2 activation by MT1-MMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Sequence motifs of tissue inhibitor of metalloproteinases 2 (TIMP-2) determining progelatinase A (proMMP-2) binding and activation by membrane-type metalloproteinase 1 (MT1-MMP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

Combination of Tumor Necrosis Factor-α Ablation and Matrix Metalloproteinase Inhibition Prevents Heart Failure After Pressure Overload in Tissue Inhibitor of Metalloproteinase-3 Knock-Out Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512009200

21 January 2018

Identifiers

DOI

10.1074/JBC.M512009200

1 reference

19 September 2017

1 reference