(Q40325635)

19 September 2017

1 reference

title

Drug metabolites in renal failure: pharmacokinetic and clinical implications (English)

1 reference

19 September 2017

1 reference

R K Verbeeck

1

1 reference

19 September 2017

R A Branch

series ordinal

2

1 reference

19 September 2017

G R Wilkinson

series ordinal

3

1 reference

19 September 2017

1 September 1981

1 reference

Clinical Pharmacokinetics

19 September 2017

1 reference

19 September 2017

6

1 reference

19 September 2017

5

1 reference

19 September 2017

329-345

1 reference

https://scigraph.springernature.com/pub.10.2165/00003088-198106050-00001

19 September 2017

0 references

cites work

Antiarrhythmic efficacy, pharmacokinetics and safety of N-acetylprocainamide in human subjects: Comparison with procainamide

1 reference

12 December 2020

Comparison of the acetylation of procainamide and sulfadimidine in man

1 reference

12 December 2020

Relation between serum quinidine levels and renal function. Studies in normal subjects and patients with congestive failure and renal insufficiency

1 reference

12 December 2020

Diseases and Drug Protein Binding

1 reference

12 December 2020

Kinetics of salicylate elimination by anephric patients

1 reference

12 December 2020

Plasma and urine concentrations of acebutolol and its acetyl metabolite in patients with renal functional impairment

1 reference

12 December 2020

The metabolism of antipyrine in patients with chronic renal failure

1 reference

12 December 2020

The effect of impaired renal function on the plasma concentration and urinary excretion of metoprolol metabolites

1 reference

12 December 2020

Clinical pharmacokinetics of procainamide infusions in relation to acetylator phenotype

1 reference

12 December 2020

Acebutolol metabolite plasma concentration during chronic oral therapy

1 reference

12 December 2020

Beta-adrenoceptor blocking properties and cardioselectivity of M & B 17,803A

1 reference

12 December 2020

Quinidine Elimination in Patients with Congestive Heart Failure or Poor Renal Function

1 reference

12 December 2020

Drug dosage in renal disease

1 reference

12 December 2020

Inhibition of Drug Metabolism by Hydroxylated Metabolites: Cross‐Inhibition and Specificity

1 reference

12 December 2020

Renal Failure, Drug Pharmacokinetics and Drug Action

1 reference

12 December 2020

Is phenytoin metabolism dose-dependent by enzyme saturation or by feedback inhibition?

1 reference

12 December 2020

Cardio-Respiratory Toxicity of Propoxyphene and Norpropoxyphene in Conscious Rabbits*

1 reference

12 December 2020

The pharmacokinetic profile of oxazepam

1 reference

12 December 2020

Plasma propranolol levels in adults With observations in four children

1 reference

12 December 2020

Control of clofibrate toxicity in uremic hypertriglyceridemia

1 reference

12 December 2020

The question of cumulation of digoxin metabolites in renal failure

1 reference

12 December 2020

Electrophysiologic properties of propoxyphene and norpropoxyphene in canine cardiac conducting tissues in vitro and in vivo

1 reference

12 December 2020

Elimination of procainamide in end stage renal failure

1 reference

12 December 2020

Cumulation of N-acetylprocainamide, an active metabolite of procainamide, in patients with impaired renal function

1 reference

12 December 2020

Digoxin pharmacokinetics: multicompartmental analysis and its clinical implications

1 reference

12 December 2020

Clofibrate disposition in renal failure and acute and chronic liver disease

1 reference

12 December 2020

Binding to cytochrome P-450 and metabolism of desmethylimipramine and metabolites in rat liver microsomes

1 reference

12 December 2020

Disposition of propranolol. V. Drug accumulation and steady-state concentrations during chronic oral administration in man.

1 reference

12 December 2020

N‐acetylprocainamide levels in patients with end‐stage renal failure

1 reference

12 December 2020

The acetylator phenotype of patients with systemic lupus erythematosus

1 reference

12 December 2020

Renal clearance of oxipurinol, the chief metabolite of allopurinol

1 reference

12 December 2020

Oxazepam disposition in uremic patients

1 reference

12 December 2020

Disposition of 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one (lorazepam) in humans. Determination of the drug by electron capture gas chromatography

1 reference

12 December 2020

Hypotensive effect of methyldopa in renal failure associated with hypertension

1 reference

12 December 2020

Altered protein binding of diphenylhydamtoin in uremic plasma

1 reference

12 December 2020

Quantitation in plasma and urine of acebutolol and a major metabolite with preliminary observations on their disposition kinetics in man

1 reference

12 December 2020

Administration of tritiated digoxin with and without a loading dose. A metabolic study

1 reference

12 December 2020

Adverse drug effects in relation to renal function

1 reference

12 December 2020

Diflunisal: a review of its pharmacological properties and therapeutic use in pain and musculoskeletal strains and sprains and pain in osteoarthritis

1 reference

12 December 2020

The effect of N-demethylation on certain pharmacologic actions of morphine, codeine, and meperidine in the mouse

1 reference

12 December 2020

Clofibrate treatment of hyperlipidemia in chronic renal failure

1 reference

12 December 2020

Pharmacokinetics of acetaminophen elimination by anephric patients

1 reference

12 December 2020

Propranolol disposition in renal failure

1 reference

12 December 2020

Mechanisms of nonlinear disposition kinetics of sulfamethazine

1 reference

12 December 2020

Conjugation of methyldopa in renal failure

1 reference

12 December 2020

Pharmacokinetic and pharmacodynamic properties of metoprolol in patients with impaired renal function

1 reference

12 December 2020

Clinical consequences of polymorphic acetylation of basic drugs

1 reference

12 December 2020

The specificity of the digoxin radioimmunoassay procedure

1 reference

12 December 2020

Pharmacokinetics of digoxin in normal subjects after intravenous bolus and infusion doses

1 reference

12 December 2020

Plasma half-life of clofibric acid in renal failure

1 reference

12 December 2020

Clofibrate-induced muscle damage in patients with chronic renal failure

1 reference

12 December 2020

Antiarrhythmic efficacy of N-acetylprocainamide in patients with premature ventricular contractions

1 reference

12 December 2020

Biotransformation and excretion of lorazepam in patients with chronic renal failure

1 reference

12 December 2020

Metabolic disposition of methyldopa in hypertensive and renal-insufficient children

1 reference

12 December 2020

The metabolism of tritiated digoxin in renal insufficiency in dogs and man

1 reference

12 December 2020

Acetylation polymorphism of sulfapyridine in patients with ulcerative colitis and Crohn's disease

1 reference

12 December 2020

Commentary: a physiological approach to hepatic drug clearance

1 reference

12 December 2020

Determination of procainamide acetylator status

1 reference

12 December 2020

Dose-ranging trial of N-acetylprocainamide in patients with premature ventricular contractions

1 reference

12 December 2020

Correction of protein binding defect in uremic sera by charcoal treatment

1 reference

12 December 2020

Pharmacokinetic studies on the selective beta1-receptor antagonist metoprolol in man.

1 reference

12 December 2020

Plasma concentration of ?-methyldopa and sulphate conjugate after oral administration of methyldopa and intravenous administration of methyldopa and methyldopa hydrochloride ethyl ester

1 reference

12 December 2020

Saliva and plasma levels and plasma protein binding of clofibrinic acid in uremic patients

1 reference

12 December 2020

Drug Prescribing in Renal Failure

1 reference

12 December 2020

Polymorphic acetylation of procainamide in man

1 reference

12 December 2020

Pharmacokinetics of oxazepam in healthy volunteers

1 reference

12 December 2020

Accumulation of normeperidine, an active metabolite of meperidine, in patients with renal failure of cancer

1 reference

12 December 2020

Diphenylhydantoin Metabolism in Uremia

1 reference

12 December 2020

Evidence for a trimodal pattern of acetylation of isoniazid in uremic subjects

1 reference

12 December 2020

Drug interactions and clinical pharmacokinetics

1 reference

12 December 2020

Urinary Excretion and Plasma Levels of Sulphonamides in Patients with Renal Impairment

1 reference

12 December 2020

Drug distribution in renal failure

1 reference

12 December 2020

Polymorphic acetylation of procaine amide in healthy subjects

1 reference

12 December 2020

The polymorphic acetylation of sulphapyridine in man

1 reference

12 December 2020

High-pressure liquid chromatographic analysis of drugs in biological fluids. V. Analysis of acebutolol and its major metabolite

1 reference

12 December 2020

The influence of polar and non-polar digoxin and digitoxin metabolites on the 86Rb-uptake of human erythrocytes and the contractility of guinea pig papillary muscles

1 reference

12 December 2020

Determination of acetylator status in uraemia

1 reference

12 December 2020

Divergence in pharmacokinetic parameters of quinidine obtained by specific and nonspecific assay methods

1 reference

12 December 2020

Polymorphic Acetylation of the Antibacterials, Sulfamethazine and Dapsone, in South Indian Subjects *

1 reference

12 December 2020

Pharmacokinetics of acebutolol in patients with all grades of renal failure

1 reference

12 December 2020

The predictable relationship between plasma levels and dose during chronic propranolol therapy

1 reference

12 December 2020

Drug therapy. Sodium nitroprusside

1 reference

12 December 2020

N-Acetylprocainamide pharmacokinetics in functionally anephric patients before and after perturbation by hemodialysis

1 reference

12 December 2020

Active drug metabolites and renal failure

1 reference

12 December 2020

Decreased body clearance of diflunisal in renal insufficiency-an alternative explanation [letter]

1 reference

12 December 2020

Elimination of isoniazid in patients with impaired renal function

1 reference

12 December 2020

Propoxyphene and norpropoxyphene plasma concentrations in the anephric patient

1 reference

12 December 2020

Propranolol glucuronide cumulation during long-term propranolol therapy: a proposed storage mechanism for propranolol

1 reference

12 December 2020

Plasma levels and renal excretion of phenytoin and its metabolites in patients with renal failure

1 reference

12 December 2020

Inhibition of Phenylbutazone Elimination by Its Metabolite Oxyphenbutazone

1 reference

12 December 2020

Single- and multiple-dose kinetics of oral lorazepam in humans: the predictability of accumulation

1 reference

12 December 2020

Simultaneous analysis of dapsone and monoacetyldapsone employing high performance liquid chromatography: a rapid method for determination of acetylator phenotype

1 reference

12 December 2020

Pharmacokinetics of diflunisal elimination in patients with renal insufficiency [proceedings]

1 reference

12 December 2020

Protein binding of drugs in uremic and normal serum: the role of endogenous binding inhibitors

1 reference

12 December 2020

The biotransformation of drugs in renal failure

1 reference

12 December 2020

Kinetic discrimination of three sulfamethazine acetylation phenotypes

1 reference

12 December 2020

Kinetics of procainamide and N-acetylprocainamide in renal failure

1 reference

12 December 2020

Acetylator phenotyping of tuberculosis patients using matrix isoniazid or sulphadimidine and its prognostic significance for treatment with several intermittent isoniazid-containing regimens

1 reference

12 December 2020

Polymorphic acetylation of sulphadimidine in normal and uraemic man

1 reference

12 December 2020

THE METABOLISM OF DIGOXIN IN NORMAL SUBJECTS

1 reference

12 December 2020

The binding of drugs to plasma proteins and the interpretation of measurements of plasma concentrations of drugs in patients with poor renal function

1 reference

12 December 2020

Physiological disposition and metabolism of 5-(2',4'-difluorophenyl)salicyclic acid, a new salicylate

1 reference

12 December 2020

Pharmacokinetics in renal disease

1 reference

12 December 2020

Persistence of antibiotics in blood of patients with acute renal failure. II. Chloramphenicol and its metabolic products in the blood of patients with severe renal disease or hepatic cirrhosis

1 reference

12 December 2020

Decreased clearance of diflunisal in renal insufficiency--an alternative explanation

1 reference

12 December 2020

Long-term antiarrhythmic therapy withN-acetylprocainamide

1 reference

12 December 2020

The binding of drugs to plasma proteins from patients with poor renal function

1 reference

12 December 2020

Pharmacologically active drug metabolites: therapeutic and toxic activities, plasma and urine data in man, accumulation in renal failure

1 reference

12 December 2020

Inhibition of diphenylhydantoin elimination by its major metabolite

1 reference

12 December 2020

Spontaneous systemic lupus erythematosus and acelylator phenotype

1 reference

12 December 2020

Prediction of drug dosage in patients with renal failure using data derived from normal subjects

1 reference

12 December 2020

Biotransformation of diflunisal and renal excretion of its glucuronides in renal insufficiency

1 reference

12 December 2020

Effect of hemodialysis on propoxyphene and norpropoxyphene concentrations in blood of anephric patients

1 reference

12 December 2020

The biotransformation of oxazepam (7-chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one) in man, miniature swine and rat

1 reference

12 December 2020

Disease and Acetylation Polymorphism

1 reference

12 December 2020

Evaluation of the sulphapyridine acetylator phenotyping test in healthy subjects and in patients with cardiac and renal diseases

1 reference

12 December 2020

Dose-dependent changes in sulfamethazine kinetics in rapid and slow isoniazid acetylators

1 reference

12 December 2020

Screening methods using sulfamethazine for determining acetylator phenotype

1 reference

12 December 2020

1 reference

12 December 2020

10.2165/00003088-198106050-00001

Identifiers

DOI

1 reference

Dimensions Publication ID

19 September 2017

0 references

1 reference