(Q40331033)

English

The catalytic histidine dyad of high density lipoprotein-associated serum paraoxonase-1 (PON1) is essential for PON1-mediated inhibition of low density lipoprotein oxidation and stimulation of macrophage cholesterol efflux

scientific article published on 10 January 2006

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scholarly article

1 reference

Europe PubMed Central

19 September 2017

The catalytic histidine dyad of high density lipoprotein-associated serum paraoxonase-1 (PON1) is essential for PON1-mediated inhibition of low density lipoprotein oxidation and stimulation of macrophage cholesterol efflux (English)

1 reference

Europe PubMed Central

19 September 2017

1 reference

based on heuristic

inferred from title

author name string

Mira Rosenblat

1

1 reference

Europe PubMed Central

19 September 2017

Leonid Gaidukov

2

1 reference

Europe PubMed Central

19 September 2017

Olga Khersonsky

3

1 reference

Europe PubMed Central

19 September 2017

Jacob Vaya

4

1 reference

Europe PubMed Central

19 September 2017

Roni Oren

5

1 reference

Europe PubMed Central

19 September 2017

Dan S Tawfik

6

1 reference

Europe PubMed Central

19 September 2017

Michael Aviram

7

1 reference

Europe PubMed Central

19 September 2017

language of work or name

0 references

publication date

10 January 2006

1 reference

Europe PubMed Central

19 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

19 September 2017

281

1 reference

Europe PubMed Central

19 September 2017

11

1 reference

Europe PubMed Central

19 September 2017

7657-7665

1 reference

Europe PubMed Central

19 September 2017

Human serum Paraoxonase/Arylesterase's retained hydrophobic N-terminal leader sequence associates with HDLs by binding phospholipids : apolipoprotein A-I stabilizes activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

The importance of high-density lipoproteins for paraoxonase-1 secretion, stability, and activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Paraoxonase 1 (PON1) is present in postprandial chylomicrons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Very low density lipoproteins provide a vector for secretion of paraoxonase-1 from cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

High affinity, stability, and lactonase activity of serum paraoxonase PON1 anchored on HDL with ApoA-I.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Low paraoxonase activity predicts coronary events in the Caerphilly Prospective Study

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Combined serum paraoxonase knockout/apolipoprotein E knockout mice exhibit increased lipoprotein oxidation and atherosclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Paraoxonase (PON1) deficiency is associated with increased macrophage oxidative stress: studies in PON1-knockout mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Decreased atherosclerotic lesion formation in human serum paraoxonase transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Paraoxonase 1 overexpression in mice and its effect on high-density lipoproteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Paraoxonase 1 (PON1) attenuates macrophage oxidative status: studies in PON1 transfected cells and in PON1 transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

The Yin and Yang of oxidation in the development of the fatty streak. A review based on the 1994 George Lyman Duff Memorial Lecture

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Oxidative stress increases the expression of the CD36 scavenger receptor and the cellular uptake of oxidized low-density lipoprotein in macrophages from atherosclerotic mice: protective role of antioxidants and of paraoxonase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Paraoxonases 1, 2, and 3, oxidative stress, and macrophage foam cell formation during atherosclerosis development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Hydrocarbon fuels. Hopes for a flame-free future

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Human serum paraoxonase 1 decreases macrophage cholesterol biosynthesis: possible role for its phospholipase-A2-like activity and lysophosphatidylcholine formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Paraoxonase 1 (PON1) enhances HDL-mediated macrophage cholesterol efflux via the ABCA1 transporter in association with increased HDL binding to the cells: a possible role for lysophosphatidylcholine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Platelet-activating factor acetylhydrolase, and not paraoxonase-1, is the oxidized phospholipid hydrolase of high density lipoprotein particles

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Paraoxonase-1 does not reduce or modify oxidation of phospholipids by peroxynitrite.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Purified human serum PON1 does not protect LDL against oxidation in the in vitro assays initiated with copper or AAPH

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Directed evolution of mammalian paraoxonases PON1 and PON3 for bacterial expression and catalytic specialization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Direct detection and quantification of transition metal ions in human atherosclerotic plaques: evidence for the presence of elevated levels of iron and copper

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Tumor necrosis factor-alpha in low doses preactivates and activates macrophages by increasing their ability to produce reactive oxygen species and oxidize low-density lipoproteins: protective effect of antioxidants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Apolipoprotein A-I promotes the formation of phosphatidylcholine core aldehydes that are hydrolyzed by paraoxonase (PON-1) during high density lipoprotein oxidation with a peroxynitrite donor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Lactonase and lactonizing activities of human serum paraoxonase (PON1) and rabbit serum PON3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Structure-function relationships of apolipoprotein A-I: a flexible protein with dynamic lipid associations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Cysteine substitutions in apolipoprotein A-I primary structure modulate paraoxonase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Apolipoprotein A-I mimetic peptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

The histidine 115-histidine 134 dyad mediates the lactonase activity of mammalian serum paraoxonases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512595200

21 January 2018

Identifiers

10.1074/JBC.M512595200

1 reference

Europe PubMed Central

19 September 2017

1 reference

Europe PubMed Central

19 September 2017

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