(Q40331048)

19 September 2017

A nuclear transport signal in mammalian target of rapamycin is critical for its cytoplasmic signaling to S6 kinase 1. (English)

1 reference

19 September 2017

1 reference

Rebecca A Bachmann

1

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19 September 2017

Jeong-Ho Kim

2

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19 September 2017

Ai-Luen Wu

3

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19 September 2017

In-Hyun Park

4

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19 September 2017

Jie Chen

5

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19 September 2017

language of work or name

English

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publication date

9 January 2006

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Journal of Biological Chemistry

19 September 2017

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19 September 2017

281

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19 September 2017

7357-7363

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19 September 2017

11

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Upstream and downstream of mTOR

19 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Regulation of translation initiation by FRAP/mTOR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Two motifs in the translational repressor PHAS-I required for efficient phosphorylation by mammalian target of rapamycin and for recognition by raptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Interaction of RAFT1 with gephyrin required for rapamycin-sensitive signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Expression, enzyme activity, and subcellular localization of mammalian target of rapamycin in insulin-responsive cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Cytoplasmic-nuclear shuttling of FKBP12-rapamycin-associated protein is involved in rapamycin-sensitive signaling and translation initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

FKBP12-Rapamycin-associated Protein or Mammalian Target of Rapamycin (FRAP/mTOR) Localization in the Endoplasmic Reticulum and the Golgi Apparatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Regulation of ribosomal S6 kinase 2 by mammalian target of rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Nucleocytoplasmic shuttling of signal transducers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Rapid targeting of nuclear proteins to the cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

The FKBP12-rapamycin-binding domain is required for FKBP12-rapamycin-associated protein kinase activity and G1 progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Phosphatidic acid-mediated mitogenic activation of mTOR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Identification of a signal for rapid export of proteins from the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Protein sequence requirements for function of the human T-cell leukemia virus type 1 Rex nuclear export signal delineated by a novel in vivo randomization-selection assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

A novel nuclear export activity in HIV-1 matrix protein required for viral replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Transport into and out of the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

NPS@: network protein sequence analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Nucleocytoplasmic shuttling signals: two for the price of one.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Control of p70 s6 kinase by kinase activity of FRAP in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Sequence requirements for nuclear location of simian virus 40 large-T antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Transport between the cell nucleus and the cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

HEAT repeats in the Huntington's disease protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

Distinct domain utilization by Smad3 and Smad4 for nucleoporin interaction and nuclear import.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

The ATRs, ATMs, and TORs are giant HEAT repeat proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

FKBP12-Rapamycin-associated Protein (FRAP) Autophosphorylates at Serine 2481 under Translationally Repressive Conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512218200

21 January 2018

Identifiers

DOI

10.1074/JBC.M512218200

1 reference

19 September 2017

1 reference