(Q40331232)

19 September 2017

title

Phosphorylation marks IPF1/PDX1 protein for degradation by glycogen synthase kinase 3-dependent mechanisms (English)

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19 September 2017

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Marie-Josée Boucher

1

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Helena Edlund

object named as

Helena Edlund

series ordinal

4

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author name string

Lars Selander

series ordinal

2

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19 September 2017

Lennart Carlsson

series ordinal

3

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19 September 2017

language of work or name

English

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publication date

11 January 2006

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Journal of Biological Chemistry

19 September 2017

number of pages

9

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based on heuristic

inferred from page(s)

published in

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19 September 2017

volume

281

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19 September 2017

issue

10

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19 September 2017

page(s)

6395-6403

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Insulin-promoter-factor 1 is required for pancreas development in mice

19 September 2017

cites work

1 reference

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Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence

21 January 2018

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beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes

21 January 2018

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Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion

21 January 2018

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Increased islet apoptosis in Pdx1+/- mice

21 January 2018

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Insulin promoter factor-1 mutations and diabetes in Trinidad: identification of a novel diabetes-associated mutation (E224K) in an Indo-Trinidadian family

21 January 2018

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Does the aspartic acid to asparagine substitution at position 76 in the pancreas duodenum homeobox gene (PDX1) cause late-onset type 2 diabetes?

21 January 2018

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Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus

21 January 2018

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Missense mutations in the human insulin promoter factor-1 gene and their relation to maturity-onset diabetes of the young and late-onset type 2 diabetes mellitus in caucasians

21 January 2018

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Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor

21 January 2018

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Insulin upstream factor 1 and a novel ubiquitous factor bind to the human islet amyloid polypeptide/amylin gene promoter

21 January 2018

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Identification of cis- and trans-active factors regulating human islet amyloid polypeptide gene expression in pancreatic beta-cells

21 January 2018

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The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter

21 January 2018

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Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47.

21 January 2018

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Bridge-1, a novel PDZ-domain coactivator of E2A-mediated regulation of insulin gene transcription

21 January 2018

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Pancreas duodenum homeobox-1 transcriptional activation requires interactions with p300

21 January 2018

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The coactivator Bridge-1 increases transcriptional activation by pancreas duodenum homeobox-1 (PDX-1)

21 January 2018

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Glucose-dependent translocation of insulin promoter factor-1 (IPF-1) between the nuclear periphery and the nucleoplasm of single MIN6 beta-cells

21 January 2018

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Glucose stimulates translocation of the homeodomain transcription factor PDX1 from the cytoplasm to the nucleus in pancreatic beta-cells

21 January 2018

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Glucose stimulates the activation domain potential of the PDX-1 homeodomain transcription factor

21 January 2018

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The p38/reactivating kinase mitogen-activated protein kinase cascade mediates the activation of the transcription factor insulin upstream factor 1 and insulin gene transcription by high glucose in pancreatic beta-cells

21 January 2018

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Insulin stimulates pancreatic-duodenal homoeobox factor-1 (PDX1) DNA-binding activity and insulin promoter activity in pancreatic beta cells

21 January 2018

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Stable and functional regeneration of pancreatic beta-cell population in nSTZ-rats treated with tungstate

21 January 2018

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Regulation of insulin gene transcription by ERK1 and ERK2 in pancreatic beta cells

21 January 2018

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The transcription factor PDX-1 is post-translationally modified by O-linked N-acetylglucosamine and this modification is correlated with its DNA binding activity and insulin secretion in min6 beta-cells.

21 January 2018

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GSK-3: tricks of the trade for a multi-tasking kinase

21 January 2018

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Phosphorylation-dependent nucleocytoplasmic shuttling of pancreatic duodenal homeobox-1.

21 January 2018

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Oxidative stress-mediated, post-translational loss of MafA protein as a contributing mechanism to loss of insulin gene expression in glucotoxic beta cells

21 January 2018

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Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

21 January 2018

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Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/PI-3 kinase/p70 s6 kinase and CaM kinase pathways

21 January 2018

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Effects of tacrolimus (FK506) on human insulin gene expression, insulin mRNA levels, and insulin secretion in HIT-T15 cells

21 January 2018

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Transforming growth factor beta induction of insulin gene expression is mediated by pancreatic and duodenal homeobox gene-1 in rat insulinoma cells

21 January 2018

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Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

21 January 2018

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Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes

21 January 2018

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Direct, activating interaction between glycogen synthase kinase-3beta and p53 after DNA damage

21 January 2018

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Endoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3beta

21 January 2018

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Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3.

21 January 2018

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Regulation of the pancreatic duodenal homeobox-1 protein by DNA-dependent protein kinase

21 January 2018

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The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

21 January 2018

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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

21 January 2018

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Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

21 January 2018

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Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

21 January 2018

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The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase

21 January 2018

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GSK3 beta-dependent phosphorylation of the alpha NAC coactivator regulates its nuclear translocation and proteasome-mediated degradation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M511597200

Ser-557-phosphorylated mCRY2 is degraded upon synergistic phosphorylation by glycogen synthase kinase-3 beta.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M511597200

Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M511597200

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511597200

Increased glycogen synthase kinase-3 activity in diabetes- and obesity-prone C57BL/6J mice

21 January 2018

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Potential role of glycogen synthase kinase-3 in skeletal muscle insulin resistance of type 2 diabetes

21 January 2018

1 reference

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Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M511597200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511597200

Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511597200

Oxidative stress induces nucleo-cytoplasmic translocation of pancreatic transcription factor PDX-1 through activation of c-Jun NH(2)-terminal kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511597200

Involvement of c-Jun N-terminal kinase in oxidative stress-mediated suppression of insulin gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511597200

Glycation-dependent, reactive oxygen species-mediated suppression of the insulin gene promoter activity in HIT cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511597200

The development of potent and selective bisarylmaleimide GSK3 inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511597200

Discovery and development of GSK3 inhibitors for the treatment of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511597200

21 January 2018

Identifiers

DOI

10.1074/JBC.M511597200

1 reference

19 September 2017

1 reference