(Q40337530)

19 September 2017

A role for the scaffolding adapter GAB2 in breast cancer (English)

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19 September 2017

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Mohamed Bentires-Alj

1

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19 September 2017

Susana G Gil

2

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19 September 2017

Richard Chan

3

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19 September 2017

Zhigang C Wang

4

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19 September 2017

Yongping Wang

5

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19 September 2017

Naoko Imanaka

6

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19 September 2017

Lyndsay N Harris

7

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19 September 2017

Andrea Richardson

8

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19 September 2017

Benjamin G Neel

9

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19 September 2017

Haihua Gu

10

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19 September 2017

language of work or name

English

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publication date

20 December 2005

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19 September 2017

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19 September 2017

12

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19 September 2017

114-121

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19 September 2017

1

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https://scigraph.springernature.com/pub.10.1038/nm1341

19 September 2017

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cites work

Putting tumours in context

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7 January 2021

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7 January 2021

The "Gab" in signal transduction.

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7 January 2021

Essential role for Gab2 in the allergic response

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7 January 2021

Critical role for scaffolding adapter Gab2 in Fc gamma R-mediated phagocytosis

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7 January 2021

Epidermal Growth Factor-induced DNA Synthesis

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7 January 2021

Requirement of Gab2 for mast cell development and KitL/c-Kit signaling

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7 January 2021

The molecular scaffold Gab2 is a crucial component of RANK signaling and osteoclastogenesis

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7 January 2021

Critical role for Gab2 in transformation by BCR/ABL

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7 January 2021

Scaffolding protein Gab2 mediates fibroblast transformation by the SEA tyrosine kinase

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7 January 2021

High frequency of mutations of the PIK3CA gene in human cancers

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7 January 2021

Shp-2 tyrosine phosphatase: signaling one cell or many

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7 January 2021

The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling

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7 January 2021

Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia

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7 January 2021

Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia

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7 January 2021

Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations.

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7 January 2021

The docking protein Gab2 is overexpressed and estrogen regulated in human breast cancer

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7 January 2021

Comparative FISH mapping of Gab1 and Gab2 genes in human, mouse and rat

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7 January 2021

Cyclin D1, EMS1 and 11q13 amplification in breast cancer

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7 January 2021

Detailed map of a region commonly amplified at 11q13-->q14 in human breast carcinoma

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7 January 2021

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

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7 January 2021

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

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7 January 2021

Stochastic appearance of mammary tumors in transgenic mice carrying the MMTV/c-neu oncogene

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7 January 2021

The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini.

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7 January 2021

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is required for induction of autophagy during lumen formation in vitro

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7 January 2021

Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: implications for human breast cancer

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7 January 2021

Multiple ErbB-2/Neu Phosphorylation Sites Mediate Transformation through Distinct Effector Proteins.

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7 January 2021

SH2 domains recognize specific phosphopeptide sequences

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7 January 2021

Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases

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7 January 2021

ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini

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7 January 2021

Specific protection against breast cancers by cyclin D1 ablation

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7 January 2021

BRCA1 promoter methylation in sporadic breast tumors: relationship to gene expression profiles

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7 January 2021

AP-1 in cell proliferation and survival

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7 January 2021

Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway.

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7 January 2021

Human somatic PTPN11 mutations induce hematopoietic-cell hypersensitivity to granulocyte-macrophage colony-stimulating factor

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7 January 2021

p21-activated Kinase-1 Signaling Mediates Cyclin D1 Expression in Mammary Epithelial and Cancer Cells

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7 January 2021

Visualizing Chromosomes as Transcriptome Correlation Maps: Evidence of Chromosomal Domains Containing Co-expressed Genes—A Study of 130 Invasive Ductal Breast Carcinomas

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7 January 2021

P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-alpha and promotes hyperplasia in mammary epithelium

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7 January 2021

CCND1 and FGFR1 coamplification results in the colocalization of 11q13 and 8p12 sequences in breast tumor nuclei.

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7 January 2021

Gene expression predictors of breast cancer outcomes

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7 January 2021

Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation

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7 January 2021

New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

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7 January 2021

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

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7 January 2021

Stable suppression of tumorigenicity by virus-mediated RNA interference

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7 January 2021

Tyrosine phosphatase-epsilon activates Src and supports the transformed phenotype of Neu-induced mammary tumor cells

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7 January 2021

Identifiers

DOI

10.1038/NM1341

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19 September 2017

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