(Q40340116)

19 September 2017

title

Elucidation of the molecular mechanism underlying tumor-selective replication of the oncolytic adenovirus mutant ONYX-015. (English)

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19 September 2017

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Stefan J Ries

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19 September 2017

language of work or name

English

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publication date

1 December 2005

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19 September 2017

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19 September 2017

volume

1

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19 September 2017

issue

6

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19 September 2017

page(s)

763-766

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Heat shock phenocopies E1B-55K late functions and selectively sensitizes refractory tumor cells to ONYX-015 oncolytic viral therapy

19 September 2017

cites work

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https://api.crossref.org/works/10.2217%2F14796694.1.6.763

Oncolytic viruses for the treatment of cancer: current strategies and clinical trials.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.763

ONYX-015: mechanisms of action and clinical potential of a replication-selective adenovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.763

Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.763

Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.763

An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.763

a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.763

Adenovirus E1B proteins are required for accumulation of late viral mRNA and for effects on cellular mRNA translation and transport

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.763

The adenovirus E1B-55K transforming polypeptide modulates transport or cytoplasmic stabilization of viral and host cell mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.763

Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.763

Effects of febrile temperature on adenoviral infection and replication: implications for viral therapy of cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.763

21 January 2018

Identifiers

DOI

10.2217/14796694.1.6.763

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19 September 2017

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