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English
Oncolytic viruses for the treatment of cancer: current strategies and clinical trials.
scientific article published in September 2004
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15450242
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15450242%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
review article
1 reference
stated in
Europe PubMed Central
title
Oncolytic viruses for the treatment of cancer: current strategies and clinical trials
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15450242
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15450242%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
main subject
oncolytic virus
1 reference
based on heuristic
inferred from title
author
Christian H Brandts
series ordinal
2
1 reference
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Europe PubMed Central
PubMed publication ID
15450242
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15450242%20AND%20SRC:MED&resulttype=core&format=json
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3 January 2020
author name string
Stefan J Ries
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1
1 reference
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Europe PubMed Central
PubMed publication ID
15450242
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15450242%20AND%20SRC:MED&resulttype=core&format=json
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3 January 2020
language of work or name
English
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publication date
1 September 2004
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Europe PubMed Central
PubMed publication ID
15450242
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15450242%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
published in
Drug Discovery Today
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15450242
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15450242%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
volume
9
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15450242
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15450242%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
issue
17
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15450242
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15450242%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
page(s)
759-768
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15450242
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15450242%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
cites work
Replication-selective viruses for cancer therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncolytic viruses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Principles of tumor immunosurveillance and implications for immunotherapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Armed therapeutic viruses: strategies and challenges to arming oncolytic viruses with therapeutic genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RNA viruses as virotherapy agents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reovirus as a novel oncolytic agent
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vectors based on autonomous parvoviruses: novel tools to treat cancer?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antineoplasic activity of parvoviruses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncolytic herpes simplex virus vectors for cancer virotherapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intravascular adenoviral agents in cancer patients: lessons from clinical trials
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development of a replication-selective, oncolytic poxvirus for the treatment of human cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intergeneric poliovirus recombinants for the treatment of malignant glioma
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
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inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adenovirus E1B oncoprotein tethers a transcriptional repression domain to p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An adenovirus mutant that replicates selectively in p53-deficient human tumor cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
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retrieved
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
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inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
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inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selectivity of a replication-competent adenovirus for human breast carcinoma cells expressing the MUC1 antigen.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomerase-dependent oncolytic adenovirus for cancer treatment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
New oncolytic adenoviruses with hypoxia- and estrogen receptor-regulated replication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
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stated in
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reference URL
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retrieved
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stated in
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reference URL
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stated in
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reference URL
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stated in
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retrieved
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1 reference
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1 reference
stated in
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7 January 2021
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inferred from DOI database lookup
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1 reference
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inferred from DOI database lookup
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1 reference
stated in
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retrieved
7 January 2021
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inferred from DOI database lookup
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1 reference
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retrieved
7 January 2021
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inferred from DOI database lookup
The oncolytic virotherapy treatment platform for cancer: unique biological and biosafety points to consider
1 reference
stated in
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reference URL
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retrieved
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inferred from DOI database lookup
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1 reference
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reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
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7 January 2021
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inferred from DOI database lookup
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1 reference
stated in
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reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903221-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1359-6446(04)03221-0
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15450242
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15450242%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
PubMed publication ID
15450242
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15450242
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15450242%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
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