(Q52537791)

2 May 2018

title

A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo. (English)

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2 May 2018

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Fueyo J

1

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2 May 2018

Gomez-Manzano C

2

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2 May 2018

Alemany R

3

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2 May 2018

Lee PS

4

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2 May 2018

McDonnell TJ

5

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2 May 2018

Mitlianga P

6

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2 May 2018

Shi YX

7

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2 May 2018

Levin VA

8

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2 May 2018

Yung WK

9

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2 May 2018

Kyritsis AP

10

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2 May 2018

language of work or name

English

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publication date

1 January 2000

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2 May 2018

published in

Oncogene

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2 May 2018

volume

19

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2 May 2018

issue

1

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2 May 2018

page(s)

2-12

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2 May 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1203251

exact match

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cites work

Application of an immunoperoxidase monolayer assay for the detection of arboviral antibodies

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Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection

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An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

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An oncolytic viral mutant that delivers the CYP2B1 transgene and augments cyclophosphamide chemotherapy

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Reovirus therapy of tumors with activated Ras pathway

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Gene and chromosomal alterations associated with the development of human gliomas.

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Viral transactivating proteins

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A novel three-pronged approach to kill cancer cells selectively: concomitant viral, double suicide gene, and radiotherapy

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The functional role of tumor suppressor genes in gliomas: clues for future therapeutic strategies

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Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo

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7 January 2021

Suppression of human glioma growth by adenovirus-mediated Rb gene transfer

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7 January 2021

Characterization of p53 and p21 functional interactions in glioma cells en route to apoptosis.

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7 January 2021

Loss in expression of the retinoblastoma gene product in human gliomas is associated with advanced disease

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7 January 2021

Targeting the replication of adenoviral gene therapy vectors to lung cancer cells: the importance of the adenoviral E1b-55kD gene

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ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

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The retinoblastoma gene is involved in malignant progression of astrocytomas

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Differential expression of myc, max and RB1 genes in human gliomas and glioma cell lines

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Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells

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7 January 2021

ONYX-015: clinical data are encouraging

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Experimental Therapy of Human Glioma by Means of a Genetically Engineered Virus Mutant

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Rearrangement of the p53 gene in human osteogenic sarcomas

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Attenuated multi–mutated herpes simplex virus–1 for the treatment of malignant gliomas

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E2F: a link between the Rb tumor suppressor protein and viral oncoproteins

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7 January 2021

Beta-galactosidase gene transfer to human malignant glioma in vivo using replication-deficient retroviruses and adenoviruses

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7 January 2021

p53/E1b58kDa complex regulates adenovirus replication

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7 January 2021

Gene therapy for cancer: what have we done and where are we going?

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7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203251

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7 January 2021

Clonal expansion of p53 mutant cells is associated with brain tumour progression

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7 January 2021

Cellular targets for transformation by the adenovirus E1A proteins

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203251

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203251

1 reference

2 May 2018

1 reference

2 May 2018