(Q40340391)

English

Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor. Reduced RNA replication fitness and partial rescue by second-site mutations

scientific article published on 13 December 2005

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scholarly article

1 reference

Europe PubMed Central

19 September 2017

Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor. Reduced RNA replication fitness and partial rescue by second-site mutations (English)

1 reference

Europe PubMed Central

19 September 2017

Hepatitis C virus

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

MinKyung Yi

1

1 reference

Europe PubMed Central

19 September 2017

Xiao Tong

2

1 reference

Europe PubMed Central

19 September 2017

Angela Skelton

3

1 reference

Europe PubMed Central

19 September 2017

Robert Chase

4

1 reference

Europe PubMed Central

19 September 2017

Tong Chen

5

1 reference

Europe PubMed Central

19 September 2017

Andrew Prongay

6

1 reference

Europe PubMed Central

19 September 2017

Stephane L Bogen

7

1 reference

Europe PubMed Central

19 September 2017

Anil K Saksena

8

1 reference

Europe PubMed Central

19 September 2017

F George Njoroge

9

1 reference

Europe PubMed Central

19 September 2017

Ronald L Veselenak

10

1 reference

Europe PubMed Central

19 September 2017

Richard B Pyles

11

1 reference

Europe PubMed Central

19 September 2017

Nigel Bourne

12

1 reference

Europe PubMed Central

19 September 2017

Bruce A Malcolm

13

1 reference

Europe PubMed Central

19 September 2017

Stanley M Lemon

14

1 reference

Europe PubMed Central

19 September 2017

language of work or name

0 references

publication date

13 December 2005

1 reference

Europe PubMed Central

19 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

19 September 2017

281

1 reference

Europe PubMed Central

19 September 2017

8205-8215

1 reference

Europe PubMed Central

19 September 2017

12

1 reference

Europe PubMed Central

19 September 2017

Early changes in hepatitis C viral quasispecies during interferon therapy predict the therapeutic outcome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Longitudinal Evaluation of the Structure of Replicating and Circulating Hepatitis C Virus Quasispecies in Nonprogressive Chronic Hepatitis C Patients

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Acquisition of multi-PI (protease inhibitor) resistance in HIV-1 in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3' nontranslated region are essential for virus replication in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

In vitro resistance studies of hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061: structural analysis indicates different resistance mechanisms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

In Vitro Selection and Characterization of Hepatitis C Virus Serine Protease Variants Resistant to an Active-Site Peptide Inhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Mutations conferring resistance to a potent hepatitis C virus serine protease inhibitor in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine Protease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Subgenomic hepatitis C virus replicons inducing expression of a secreted enzymatic reporter protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Efficient initiation of HCV RNA replication in cell culture

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Screening for hepatitis C virus antiviral activity with a cell-based secreted alkaline phosphatase reporter replicon system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Adaptive mutations producing efficient replication of genotype 1a hepatitis C virus RNA in normal Huh7 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Construction, expression, and characterization of a novel fully activated recombinant single-chain hepatitis C virus protease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

A continuous spectrophotometric assay for the hepatitis C virus serine protease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

High-throughput screening of enzyme inhibitors: automatic determination of tight-binding inhibition constants.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Expression and purification of an active, full-length hepatitis C viral NS4A.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease-helicase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Hepatitis C virus NS3-4A serine protease inhibitors: SAR of P'2 moiety with improved potency

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Mapping the active site of papain with the aid of peptide substrates and inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Conserved C-terminal threonine of hepatitis C virus NS3 regulates autoproteolysis and prevents product inhibition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Implications of antiretroviral resistance on viral fitness

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Changes in human immunodeficiency virus type 1 Gag at positions L449 and P453 are linked to I50V protease mutants in vivo and cause reduction of sensitivity to amprenavir and improved viral fitness in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510246200

21 January 2018

Identifiers

10.1074/JBC.M510246200

1 reference

Europe PubMed Central

19 September 2017

1 reference

Europe PubMed Central

19 September 2017

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