(Q40345737)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16319067%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

title

RPE65 is an iron(II)-dependent isomerohydrolase in the retinoid visual cycle (English)

1 reference

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9 January 2020

5

1 reference

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9 January 2020

author name string

Gennadiy Moiseyev

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16319067%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Yusuke Takahashi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16319067%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Ying Chen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16319067%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

S Gentleman

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16319067%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Rosalie K Crouch

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16319067%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Jian-Xing Ma

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16319067%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

language of work or name

English

0 references

publication date

30 November 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16319067%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

9 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16319067%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

volume

281

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16319067%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16319067%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

page(s)

2835-2840

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Confronting complexity: the interlink of phototransduction and retinoid metabolism in the vertebrate retina

9 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

The biochemistry of the visual cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

Retinyl esters are the substrate for isomerohydrolase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

All-trans-retinyl esters are the substrates for isomerization in the vertebrate visual cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

RPE65 is the isomerohydrolase in the retinoid visual cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

Rpe65 is the retinoid isomerase in bovine retinal pigment epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

Mutations in RPE65 cause Leber's congenital amaurosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

Mutations in the RPE65 gene in patients with autosomal recessive retinitis pigmentosa or leber congenital amaurosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

Genetic defects in vitamin A metabolism of the retinal pigment epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

Gene therapy restores vision in a canine model of childhood blindness

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

Recombinant adeno-associated virus type 2-mediated gene delivery into the Rpe65-/- knockout mouse eye results in limited rescue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

Identification, expression, and substrate specificity of a mammalian beta-carotene 15,15'-dioxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

Filling the gap in vitamin A research. Molecular identification of an enzyme cleaving beta-carotene to retinal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

Cloning and characterization of a human beta,beta-carotene-15,15'-dioxygenase that is highly expressed in the retinal pigment epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

Identification of conserved histidines and glutamic acid as key residues for isomerohydrolase activity of RPE65, an enzyme of the visual cycle in the retinal pigment epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

Mutation of key residues of RPE65 abolishes its enzymatic role as isomerohydrolase in the visual cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

A specific stain for the detection of nonheme iron proteins in polyacrylamide gels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

Dealing with iron: common structural principles in proteins that transport iron and heme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

Membrane phospholipids as an energy source in the operation of the visual cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

Biochemical properties of purified recombinant human beta-carotene 15,15'-monooxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

Reduction of Fe(III) ions complexed to physiological ligands by lipoyl dehydrogenase and other flavoenzymes in vitro: implications for an enzymatic reduction of Fe(III) ions of the labile iron pool

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

Regulation of isomerohydrolase activity in the visual cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

Oxygen activating nonheme iron enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

The structure of a retinal-forming carotenoid oxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508903200

21 January 2018

Identifiers

DOI

10.1074/JBC.M508903200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16319067%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference