(Q40347662)

19 September 2017

cIAP2 is highly expressed in Hodgkin-Reed-Sternberg cells and inhibits apoptosis by interfering with constitutively active caspase-3. (English)

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19 September 2017

Horst Dürkop

1

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19 September 2017

Burkhard Hirsch

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2

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19 September 2017

Corinna Hahn

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3

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19 September 2017

Harald Stein

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4

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19 September 2017

25 November 2005

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Journal of Molecular Medicine

19 September 2017

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19 September 2017

84

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19 September 2017

2

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19 September 2017

132-141

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https://scigraph.springernature.com/pub.10.1007/s00109-005-0003-7

19 September 2017

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cites work

Low frequency of FAS mutations in Reed-Sternberg cells of Hodgkin's lymphoma

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00109-005-0003-7

Constitutive expression of c-FLIP in Hodgkin and Reed-Sternberg cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00109-005-0003-7

CD30 signals integrate expression of cytotoxic effector molecules, lymphocyte trafficking signals, and signals for proliferation and apoptosis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00109-005-0003-7

Epstein-Barr virus latent membrane protein expression in Hodgkin and Reed-Sternberg cells

21 January 2018

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12 December 2020

Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells.

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12 December 2020

High numbers of active caspase 3-positive Reed-Sternberg cells in pretreatment biopsy specimens of patients with Hodgkin disease predict favorable clinical outcome.

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12 December 2020

Immunolocalization of the ICE/Ced-3-family protease, CPP32 (Caspase-3), in non-Hodgkin's lymphomas, chronic lymphocytic leukemias, and reactive lymph nodes

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12 December 2020

Clonal deleterious mutations in the IkappaBalpha gene in the malignant cells in Hodgkin's lymphoma

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12 December 2020

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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12 December 2020

The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas

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12 December 2020

Mitochondria and apoptosis

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12 December 2020

Aberrant NF-kappaB2/p52 expression in Hodgkin/Reed-Sternberg cells and CD30-transformed rat fibroblasts

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12 December 2020

Gene expression by single Reed-Sternberg cells: pathways of apoptosis and activation

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12 December 2020

Expression of the cellular FLICE-inhibitory protein (c-FLIP) protects Hodgkin's lymphoma cells from autonomous Fas-mediated death

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12 December 2020

A novel gene, MALT1 at 18q21, is involved in t(11;18) (q21;q21) found in low-grade B-cell lymphoma of mucosa-associated lymphoid tissue

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12 December 2020

Immunohistochemical analysis of interleukin-1beta-converting enzyme/Ced-3 family protease, CPP32/Yama/Caspase-3, in Hodgkin's disease

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12 December 2020

Production of a monoclonal antibody specific for Hodgkin and Sternberg–Reed cells of Hodgkin's disease and a subset of normal lymphoid cells

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12 December 2020

Cultivated H-RS cells are resistant to CD95L-mediated apoptosis despite expression of wild-type CD95.

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12 December 2020

Expression of functional CD40 antigen on Reed-Sternberg cells and Hodgkin's disease cell lines

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12 December 2020

Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF.

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12 December 2020

Tumor necrosis factor alpha sensitizes malignant cells to chemotherapeutic drugs via the mitochondrial apoptosis pathway independently of caspase-8 and NF-kappaB.

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12 December 2020

Nuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity

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12 December 2020

Ligand-independent signaling by overexpressed CD30 drives NF-kappaB activation in Hodgkin-Reed-Sternberg cells

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12 December 2020

Overexpression of I kappa B alpha without inhibition of NF-kappaB activity and mutations in the I kappa B alpha gene in Reed-Sternberg cells.

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12 December 2020

Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes)

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12 December 2020

c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis

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12 December 2020

In vitrotranscription of two Epstein-Barr virus specified small RNA molecules

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12 December 2020

XIAP-mediated caspase inhibition in Hodgkin's lymphoma-derived B cells

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12 December 2020

Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha.

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12 December 2020

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

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12 December 2020

MEK/ERK pathway is aberrantly active in Hodgkin disease: a signaling pathway shared by CD30, CD40, and RANK that regulates cell proliferation and survival

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12 December 2020

IAPs, RINGs and ubiquitylation

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12 December 2020

Expression of CD40 ligand (CD154) in B and T lymphocytes of Hodgkin disease: potential therapeutic significance.

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12 December 2020

The role of eosinophils in the pathobiology of Hodgkin's disease

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12 December 2020

Differential expression and function of A20 and TRAF1 in Hodgkin lymphoma and anaplastic large cell lymphoma and their induction by CD30 stimulation

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12 December 2020

CD30-induced up-regulation of the inhibitor of apoptosis genes cIAP1 and cIAP2 in anaplastic large cell lymphoma cells

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12 December 2020

Expression of Fas and Fas Ligand in Hodgkin's Disease

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12 December 2020

Death receptors: signaling and modulation

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12 December 2020

10.1007/S00109-005-0003-7

Identifiers

DOI

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19 September 2017

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