(Q40349264)

19 September 2017

title

Pneumococci induced TLR- and Rac1-dependent NF-kappaB-recruitment to the IL-8 promoter in lung epithelial cells (English)

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19 September 2017

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8

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19 September 2017

Michael Kracht

9

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Stefan Hippenstiel

12

object named as

Stefan Hippenstiel

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19 September 2017

11

Norbert Suttorp

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19 September 2017

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Bernd Schmeck

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19 September 2017

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Bastian Opitz

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19 September 2017

5

Andreas C Hocke

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19 September 2017

Sylvia Huber

2

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19 September 2017

Kerstin Moog

3

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19 September 2017

Janine Zahlten

4

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19 September 2017

Sven Hammerschmidt

7

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19 September 2017

Simone Rosseau

10

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19 September 2017

publication date

18 November 2005

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American Journal of Physiology - Lung Cellular and Molecular Physiology

19 September 2017

published in

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19 September 2017

volume

290

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19 September 2017

issue

4

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19 September 2017

page(s)

L730-L737

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Recognition of pathogen-associated molecular patterns by TLR family

19 September 2017

cites work

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RhoA/Rho-associated kinase pathway selectively regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via activation of I kappa B kinase beta and phosphorylation of RelA/p65.

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Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway

21 January 2018

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Expression of functional toll-like receptor-2 and -4 on alveolar epithelial cells.

21 January 2018

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Streptococcus pneumoniae colonisation: the key to pneumococcal disease

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Rho and Rac take center stage

21 January 2018

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Shaping the nuclear action of NF-kappaB

21 January 2018

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Pneumolysin activates the synthesis and release of interleukin-8 by human neutrophils in vitro.

21 January 2018

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Toll-like receptor 2-deficient mice are highly susceptible to Streptococcus pneumoniae meningitis because of reduced bacterial clearing and enhanced inflammation.

21 January 2018

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Ectodomains 3 and 4 of human polymeric Immunoglobulin receptor (hpIgR) mediate invasion of Streptococcus pneumoniae into the epithelium

21 January 2018

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Identification and function of cyclic nucleotide phosphodiesterase isoenzymes in airway epithelial cells

21 January 2018

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Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

21 January 2018

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Epidemiology of community-acquired respiratory tract infections in adults. Incidence, etiology, and impact

21 January 2018

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Activation of NF-kappaB and IL-8 by Yersinia enterocolitica invasin protein is conferred by engagement of Rac1 and MAP kinase cascades

21 January 2018

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Pneumococcal lipoteichoic acid (LTA) is not as potent as staphylococcal LTA in stimulating Toll-like receptor 2.

21 January 2018

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Rho protein inactivation induced apoptosis of cultured human endothelial cells

21 January 2018

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Pneumococcal virulence factors: structure and function

21 January 2018

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Transactivation by the p65 subunit of NF-kappaB in response to interleukin-1 (IL-1) involves MyD88, IL-1 receptor-associated kinase 1, TRAF-6, and Rac1

21 January 2018

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The innate immune response to pneumococcal lung infection: the untold story.

21 January 2018

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Monoacyl lipoteichoic acid from pneumococci stimulates human cells but not mouse cells

21 January 2018

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Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide

21 January 2018

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Toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defense

21 January 2018

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Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products.

21 January 2018

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Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection

21 January 2018

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Penicillin enhances the toll-like receptor 2-mediated proinflammatory activity of Streptococcus pneumoniae.

21 January 2018

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The pneumococcus: carriage, disease and conjugate vaccines

21 January 2018

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Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae

21 January 2018

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The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

21 January 2018

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

21 January 2018

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Importance of extra- and intracellular domains of TLR1 and TLR2 in NFkappa B signaling

21 January 2018

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Rho protein inhibition blocks cyclooxygenase-2 expression by proinflammatory mediators in endothelial cells

21 January 2018

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Streptococcus pneumoniae-induced caspase 6-dependent apoptosis in lung epithelium

21 January 2018

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Streptococcus pneumoniae-induced p38 MAPK-dependent phosphorylation of RelA at the interleukin-8 promotor

21 January 2018

1 reference

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Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved

21 January 2018

1 reference

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Lipopolysaccharide and pneumococcal cell wall components activate the mitogen activated protein kinases (MAPK) erk-1, erk-2, and p38 in astrocytes

21 January 2018

1 reference

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The IL-1 receptor and Rho directly associate to drive cell activation in inflammation

21 January 2018

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Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

21 January 2018

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Phosphoinositide 3-kinase and Akt occupy central roles in inflammatory responses of Toll-like receptor 2-stimulated neutrophils

21 January 2018

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Interleukin-8: a very important chemokine of the human airway epithelium.

21 January 2018

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Discrimination of bacterial lipoproteins by Toll-like receptor 6

21 January 2018

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Mycobacterial lipoarabinomannan mediates physical interactions between TLR1 and TLR2 to induce signaling

21 January 2018

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The low molecular weight GTPase RhoA and atypical protein kinase Czeta are required for TLR2-mediated gene transcription

21 January 2018

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The Induction of Meningeal Inflammation by Components of the Pneumococcal Cell Wall

21 January 2018

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The relative role of bacterial cell wall and capsule in the induction of inflammation in pneumococcal meningitis

21 January 2018

1 reference

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Recognition of pneumococcal peptidoglycan: an expanded, pivotal role for LPS binding protein

21 January 2018

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High concentrations of lipopolysaccharide-binding protein in serum of patients with severe sepsis or septic shock inhibit the lipopolysaccharide response in human monocytes

21 January 2018

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10.1152/AJPLUNG.00271.2005

21 January 2018

Identifiers

DOI

1 reference

19 September 2017

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