(Q40351377)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16288207%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

title

Regulation of p53 and suppression of apoptosis by the soluble guanylyl cyclase/cGMP pathway in human ovarian cancer cells (English)

1 reference

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9 January 2020

1 reference

5

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9 January 2020

author name string

M Fraser

1

1 reference

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9 January 2020

S L Chan

2

1 reference

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9 January 2020

S S L Chan

3

1 reference

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9 January 2020

R R Fiscus

4

1 reference

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9 January 2020

language of work or name

English

0 references

publication date

1 April 2006

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9 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16288207%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

volume

25

1 reference

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9 January 2020

issue

15

1 reference

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9 January 2020

page(s)

2203-2212

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209251

9 January 2020

exact match

0 references

cites work

Regulation of p53 function and stability by phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Guanylyl cyclase inhibitors NS2028 and ODQ and protein kinase G (PKG) inhibitor KT5823 trigger apoptotic DNA fragmentation in immortalized uterine epithelial cells: anti-apoptotic effects of basal cGMP/PKG

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Nitric oxide as a regulator in preimplantation embryo development and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Akt pathway mediates a cGMP-dependent survival role of nitric oxide in cerebellar granule neurones

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Role of endogenous nitric oxide and peroxynitrite formation in the survival and death of motor neurons in culture.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Nitric oxide regulates oestrogen-activated signalling pathways at multiple levels through cyclic GMP-dependent recruitment of insulin receptor substrate 1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Involvement of cyclic GMP and protein kinase G in the regulation of apoptosis and survival in neural cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Natriuretic peptides inhibit apoptosis and prolong the survival of serum-deprived PC12 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Control of survival of proliferating L1210 cells by soluble guanylate cyclase and p44/42 mitogen-activated protein kinase modulators

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Nitric oxide prevents 6-hydroxydopamine-induced apoptosis in PC12 cells through cGMP-dependent PI3 kinase/Akt activation

1 reference

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7 January 2021

Prognostic Significance of p53 Mutation and p53 Overexpression in Advanced Epithelial Ovarian Cancer: A Gynecologic Oncology Group Study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Nitric oxide prevents oxidised LDL-induced p53 accumulation, cytochrome c translocation, and apoptosis in macrophages via guanylate cyclase stimulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Nitric oxide-mediated promotion of mammary tumour cell migration requires sequential activation of nitric oxide synthase, guanylate cyclase and mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Nitric oxide promotes murine mammary tumour growth and metastasis by stimulating tumour cell migration, invasiveness and angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Apoptosis. Its significance in cancer and cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Nitric oxide protects PC12 cells from serum deprivation-induced apoptosis by cGMP-dependent inhibition of caspase signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

The inhibitors of apoptosis (IAPs) and their emerging role in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Mutation and expression of the TP53 gene in early stage epithelial ovarian carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Apoptosis, intrinsic radiosensitivity and prediction of radiotherapy response in cervical carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Human ovarian cancer and cisplatin resistance: possible role of inhibitor of apoptosis proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

p53 has a direct apoptogenic role at the mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

cGMP mediates the vascular and platelet actions of nitric oxide: confirmation using an inhibitor of the soluble guanylyl cyclase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Effect of YC-1, an NO-independent, superoxide-sensitive stimulator of soluble guanylyl cyclase, on smooth muscle responsiveness to nitrovasodilators

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Akt enhances Mdm2-mediated ubiquitination and degradation of p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Characterization of NS 2028 as a specific inhibitor of soluble guanylyl cyclase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

The IARC TP53 database: new online mutation analysis and recommendations to users

1 reference

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7 January 2021

Nitric-oxide production by murine mammary adenocarcinoma cells promotes tumor-cell invasiveness

1 reference

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7 January 2021

Site of injury-directed induction of heme oxygenase-1 and -2 in experimental spinal cord injury: differential functions in neuronal defense mechanisms?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Effect of extracellular signal-regulated kinase on p53 accumulation in response to cisplatin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Caspase 3-mediated focal adhesion kinase processing in human ovarian cancer cells: possible regulation by X-linked inhibitor of apoptosis protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

The role of apoptosis in gynaecological malignancies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

DNA damage induces phosphorylation of the amino terminus of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Natriuretic peptides and nitric oxide induce endothelial apoptosis via a cGMP-dependent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Depletion of endogenous nitric oxide enhances cisplatin-induced apoptosis in a p53-dependent manner in melanoma cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

nitric oxide triggers the phosphatidylinositol 3-kinase/Akt survival pathway in insulin-producing RINm5F cells by arousing Src to activate insulin receptor substrate-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Urine cyclic nucleotide concentrations in cancer and other conditions; cyclic GMP: a potential marker for cancer treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Cyclic GMP in urine to monitor the response to ovarian cancer to therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Mutations in serines 15 and 20 of human p53 impair its apoptotic activity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Resistance of human ovarian cancer cells to tumor necrosis factor alpha is a consequence of nuclear factor kappaB-mediated induction of Fas-associated death domain-like interleukin-1beta-converting enzyme-like inhibitory protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209251

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209251

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16288207%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 January 2020

1045310181

0 references

1 reference