(Q40352167)

19 September 2017

title

Hsp90 inhibitors cause G2/M arrest associated with the reduction of Cdc25C and Cdc2 in lung cancer cell lines (English)

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19 September 2017

Megumi Senju

1

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19 September 2017

Naoko Sueoka

2

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19 September 2017

Akemi Sato

3

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19 September 2017

Kentaro Iwanaga

4

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19 September 2017

Yukinori Sakao

5

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19 September 2017

Shinji Tomimitsu

6

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19 September 2017

Masaki Tominaga

7

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19 September 2017

Koji Irie

8

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19 September 2017

Shinichiro Hayashi

9

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19 September 2017

Eisaburo Sueoka

10

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19 September 2017

publication date

9 November 2005

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Journal of Cancer Research and Clinical Oncology

19 September 2017

published in

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19 September 2017

volume

132

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19 September 2017

issue

3

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19 September 2017

page(s)

150-158

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https://scigraph.springernature.com/pub.10.1007/s00432-005-0047-7

19 September 2017

exact match

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cites work

Radiation sensitization of human cancer cells in vivo by inhibiting the activity of PI3K using LY294002.

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00432-005-0047-7

Potential role for epidermal growth factor receptor inhibitors in combined-modality therapy for non-small-cell lung cancer

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00432-005-0047-7

Cell cycle regulation by the Cdc25 phosphatase family

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00432-005-0047-7

Role of the heat shock response and molecular chaperones in oncogenesis and cell death

21 January 2018

1 reference

12 December 2020

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

1 reference

12 December 2020

Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4

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12 December 2020

Heterogeneous nuclear ribonucleoprotein B1 as a new marker of early detection for human lung cancers

1 reference

12 December 2020

17-Allylamino-17-demethoxygeldanamycin induces the degradation of androgen receptor and HER-2/neu and inhibits the growth of prostate cancer xenografts

1 reference

12 December 2020

Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation

1 reference

12 December 2020

Comprehensive analysis of p53 gene mutation characteristics in lung carcinoma with special reference to histological subtypes.

1 reference

12 December 2020

Frequent activation of AKT in non-small cell lung carcinomas and preneoplastic bronchial lesions

1 reference

12 December 2020

Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells

1 reference

12 December 2020

Hsp90 inhibitors as novel cancer chemotherapeutic agents

1 reference

12 December 2020

Heat shock proteins in human cancer

1 reference

12 December 2020

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

1 reference

12 December 2020

Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress

1 reference

12 December 2020

Heat shock protein 90.

1 reference

12 December 2020

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

1 reference

12 December 2020

Geldanamycin-stimulated destabilization of mutated p53 is mediated by the proteasome in vivo

1 reference

12 December 2020

Multidisciplinary management of lung cancer

1 reference

12 December 2020

17-Allylamino-17-demethoxygeldanamycin activity against thyroid cancer cell lines correlates with heat shock protein 90 levels

1 reference

12 December 2020

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

1 reference

12 December 2020

Phase I trial of 17-allylamino-17-demethoxygeldanamycin in patients with advanced cancer

1 reference

12 December 2020

Geldanamycin, an inhibitor of the chaperone activity of HSP90, induces MAPK-independent cell cycle arrest

1 reference

12 December 2020

The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

1 reference

12 December 2020

Monoclonal antibody to HER-2/neureceptor modulates repair of radiation-induced DNA damage and enhances radiosensitivity of human breast cancer cells overexpressing this oncogene.

1 reference

12 December 2020

A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors

1 reference

12 December 2020

Revisions in the International System for Staging Lung Cancer

1 reference

12 December 2020

Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways

1 reference

12 December 2020

Intracellular retention and degradation of the epidermal growth factor receptor, two distinct processes mediated by benzoquinone ansamycins

1 reference

12 December 2020

Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C.

1 reference

12 December 2020

Posttranslational mechanisms contribute to the suppression of specific cyclin:CDK complexes by all-trans retinoic acid in human bronchial epithelial cells.

1 reference

12 December 2020

Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins

1 reference

12 December 2020

Phase I pharmacokinetic-pharmacodynamic study of 17-(allylamino)-17-demethoxygeldanamycin (17AAG, NSC 330507), a novel inhibitor of heat shock protein 90, in patients with refractory advanced cancers

1 reference

12 December 2020

Enhanced cell killing induced by the combination of radiation and the heat shock protein 90 inhibitor 17-allylamino-17- demethoxygeldanamycin: a multitarget approach to radiosensitization

1 reference

12 December 2020

Arsenite-induced Cdc25C Degradation is through the KEN-box and Ubiquitin-proteasome Pathway

1 reference

12 December 2020

Inhibition of heat shock protein 90 function down-regulates Akt kinase and sensitizes tumors to Taxol

1 reference

12 December 2020

The cdc25 protein controls tyrosine dephosphorylation of the cdc2 protein in a cell-free system

1 reference

12 December 2020

Potent activity of a novel dimeric heat shock protein 90 inhibitor against head and neck squamous cell carcinoma in vitro and in vivo.

1 reference

12 December 2020

10.1007/S00432-005-0047-7

Identifiers

DOI

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19 September 2017

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