(Q40357778)

19 September 2017

title

Identification of a lipid peroxidation product as a potential trigger of the p53 pathway (English)

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19 September 2017

10

Koji Uchida

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19 September 2017

Takahiro Shibata

1

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19 September 2017

Kumiko Iio

2

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19 September 2017

Yoshichika Kawai

3

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19 September 2017

Noriyuki Shibata

4

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19 September 2017

Motoko Kawaguchi

5

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19 September 2017

Sono Toi

6

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19 September 2017

Makio Kobayashi

7

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19 September 2017

Masahiko Kobayashi

8

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19 September 2017

Kenichi Yamamoto

9

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19 September 2017

language of work or name

English

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publication date

26 October 2005

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Journal of Biological Chemistry

19 September 2017

published in

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19 September 2017

volume

281

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19 September 2017

issue

2

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19 September 2017

page(s)

1196-1204

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The measurement and mechanism of lipid peroxidation in biological systems

19 September 2017

cites work

1 reference

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Apoptosis in cancer therapy: crossing the threshold

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WAF1, a potential mediator of p53 tumor suppression

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Regulation of the specific DNA binding function of p53

21 January 2018

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DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

21 January 2018

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Thymocyte apoptosis induced by p53-dependent and independent pathways.

21 January 2018

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p53 is required for radiation-induced apoptosis in mouse thymocytes

21 January 2018

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p53 induction is associated with neuronal damage in the central nervous system

21 January 2018

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p53 mutations in human cancers

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TP53 tumor suppressor gene: a model for investigating human mutagenesis

21 January 2018

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Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors

21 January 2018

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Immunohistochemical detection of a substituted 1,N(2)-ethenodeoxyguanosine adduct by omega-6 polyunsaturated fatty acid hydroperoxides in the liver of rats fed a choline-deficient, L-amino acid-defined diet.

21 January 2018

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Reaction of alpha-acetoxy-N-nitrosopiperidine with deoxyguanosine: oxygen-dependent formation of 4-oxo-2-pentenal and a 1,N2-ethenodeoxyguanosine adduct

21 January 2018

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Covalent modifications to 2'-deoxyguanosine by 4-oxo-2-nonenal, a novel product of lipid peroxidation

21 January 2018

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ATR/ATM targets are phosphorylated by ATR in response to hypoxia and ATM in response to reoxygenation

21 January 2018

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The role of ATM and ATR in the cellular response to hypoxia and re-oxygenation

21 January 2018

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

21 January 2018

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DNA damage-induced activation of ATM and ATM-dependent signaling pathways

21 January 2018

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Regulation of the p53 tumor suppressor protein

21 January 2018

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p53 is a mediator for radiation-repressed human TR2 orphan receptor expression in MCF-7 cells, a new pathway from tumor suppressor to member of the steroid receptor superfamily

21 January 2018

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Death the Fas way: regulation and pathophysiology of CD95 and its ligand

21 January 2018

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Characterization of 2'-deoxycytidine adducts derived from 4-oxo-2-nonenal, a novel lipid peroxidation product

21 January 2018

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Endogenous formation of novel halogenated 2'-deoxycytidine. Hypohalous acid-mediated DNA modification at the site of inflammation

21 January 2018

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2'-deoxycytidine in free nucleosides and double-stranded DNA as the major target of lipid peroxidation products

21 January 2018

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Induction of apoptosis in colorectal carcinoma cells treated with 4-hydroxy-2-nonenal and structurally related aldehydic products of lipid peroxidation

21 January 2018

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4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal

21 January 2018

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Mediation of c-Myc-induced apoptosis by p53.

21 January 2018

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E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination

21 January 2018

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A role for ATR in the DNA damage-induced phosphorylation of p53

21 January 2018

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Ubiquitin, proteasomes, and the regulation of intracellular protein degradation

21 January 2018

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The ubiquitin-proteasome proteolytic pathway

21 January 2018

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Selective protein degradation: a journey's end within the proteasome

21 January 2018

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Nuclear glutathione S-transferase pi prevents apoptosis by reducing the oxidative stress-induced formation of exocyclic DNA products

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M509065200

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19 September 2017

1 reference