(Q40368518)

19 September 2017

title

Rb inactivation leads to E2F1-mediated DNA double-strand break accumulation (English)

1 reference

19 September 2017

Pickering MT

1

1 reference

19 September 2017

Kowalik TF

series ordinal

2

1 reference

19 September 2017

language of work or name

English

0 references

publication date

1 February 2006

1 reference

19 September 2017

1 reference

19 September 2017

volume

25

1 reference

19 September 2017

issue

5

1 reference

19 September 2017

page(s)

746-755

1 reference

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

19 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

ATM is a target for positive regulation by E2F-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

c-Myc down-regulation increases susceptibility to cisplatin through reactive oxygen species-mediated apoptosis in M14 human melanoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

RB signaling prevents replication-dependent DNA double-strand breaks following genotoxic insult

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

Distinct roles for E2F proteins in cell growth control and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

The regulation of E2F by pRB-family proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

Myc requires distinct E2F activities to induce S phase and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

Suppression of the p53- or pRB-mediated G1 checkpoint is required for E2F-induced S-phase entry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

The Rb/E2F pathway and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

Apoptosis associated with deregulated E2F activity is dependent on E2F1 and Atm/Nbs1/Chk2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

Expression of the E2F1 transcription factor overcomes type beta transforming growth factor-mediated growth suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

Role of human Cds1 (Chk2) kinase in DNA damage checkpoint and its regulation by p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209103

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209103

1 reference

Dimensions Publication ID

19 September 2017

1006754598

0 references

1 reference