(Q40371405)

19 September 2017

title

Isozyme-specific stimulation of phospholipase C-gamma2 by Rac GTPases (English)

1 reference

19 September 2017

Thomas Piechulek

1

1 reference

19 September 2017

Tobias Rehlen

2

1 reference

19 September 2017

Claudia Walliser

3

1 reference

19 September 2017

Petra Vatter

4

1 reference

19 September 2017

Barbara Moepps

5

1 reference

19 September 2017

Peter Gierschik

6

1 reference

19 September 2017

language of work or name

English

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publication date

19 September 2005

1 reference

Journal of Biological Chemistry

19 September 2017

published in

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19 September 2017

volume

280

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19 September 2017

issue

47

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19 September 2017

page(s)

38923-38931

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Unlocking the secrets of cell signaling

19 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Protein kinase C isotypes and their specific functions: prologue

21 January 2018

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Discovery and prospect of protein kinase C research: epilogue

21 January 2018

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PIP(2) and proteins: interactions, organization, and information flow

21 January 2018

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21 January 2018

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Regulation of ion channels by phosphatidylinositol 4,5-bisphosphate

21 January 2018

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Membrane-protein interactions in cell signaling and membrane trafficking

21 January 2018

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Regulation of phosphoinositide-specific phospholipase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Stimulation of phospholipase C-beta2 by the Rho GTPases Cdc42Hs and Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Specificity and structural requirements of phospholipase C-beta stimulation by Rho GTPases versus G protein beta gamma dimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

The pleckstrin homology domain of phospholipase C-beta2 as an effector site for Rac.

21 January 2018

1 reference

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Regulation of phospholipase C gamma isoforms in haematopoietic cells: why one, not the other?

21 January 2018

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Structural and mechanistic aspects of phospholipase Cgamma regulation

21 January 2018

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Regulation of phospholipase C isozymes: activation of phospholipase C-gamma in the absence of tyrosine-phosphorylation

21 January 2018

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GAP43 stimulates inositol trisphosphate-mediated calcium release in response to hypotonicity

21 January 2018

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Phospholipase Cbeta2 binds to and inhibits phospholipase Cdelta1.

21 January 2018

1 reference

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Regulation of phospholipase C-delta1 through direct interactions with the small GTPase Ral and calmodulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

PLC-epsilon: a shared effector protein in Ras-, Rho-, and G alpha beta gamma-mediated signaling

21 January 2018

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Molecular cloning and characterization of a novel phospholipase C, PLC-eta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

A novel phospholipase C, PLC(eta)2, is a neuron-specific isozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Recombinant phospholipase Czeta has high Ca2+ sensitivity and induces Ca2+ oscillations in mouse eggs

21 January 2018

1 reference

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Rac2, a hematopoiesis-specific Rho GTPase, specifically regulates mast cell protease gene expression in bone marrow-derived mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Rac2-deficient mice display perturbed T-cell distribution and chemotaxis, but only minor abnormalities in TH 1 responses

21 January 2018

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Regulation of B-cell signal transduction by adaptor proteins

21 January 2018

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Identification, purification and characterization of a novel phosphatidylinositol-specific phospholipase C, a third member of the beta subfamily

21 January 2018

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G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase C

21 January 2018

1 reference

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Guanosine 5'-[gamma-thio]triphosphate-stimulated hydrolysis of phosphatidylinositol 4,5-bisphosphate in HL-60 granulocytes. Evidence that the guanine nucleotide acts by relieving phospholipase C from an inhibitory constraint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Stimulation of phospholipase C-beta 2 by Rho GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Comparative functional analysis of the Rac GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Expression, characterization and purification of soluble G-protein beta gamma dimers composed of defined subunits in baculovirus-infected insect cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Strong and Regulated Expression of Escherichia coli β-Galactosidase in Insect Cells with a Baculovirus Vector

21 January 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Tyrosine residues in phospholipase Cgamma 2 essential for the enzyme function in B-cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Four tyrosine residues in phospholipase C-gamma 2, identified as Btk-dependent phosphorylation sites, are required for B cell antigen receptor-coupled calcium signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Tec kinases mediate sustained calcium influx via site-specific tyrosine phosphorylation of the phospholipase Cgamma Src homology 2-Src homology 3 linker

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Vav1/2/3-null Mice Define an Essential Role for Vav Family Proteins in Lymphocyte Development and Activation but a Differential Requirement in MAPK Signaling in T and B Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Vav-family proteins in T-cell signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Bruton's tyrosine kinase regulates B cell antigen receptor-mediated JNK1 response through Rac1 and phospholipase C-gamma2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Activation of Rac-1, Rac-2, and Cdc42 by hemopoietic growth factors or cross-linking of the B-lymphocyte receptor for antigen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Activation of phospholipase C-gamma by phosphatidylinositol 3,4,5-trisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

RhoA GTPase regulates B cell receptor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Amplification of receptor signalling by Ca2+ entry-mediated translocation and activation of PLCgamma2 in B lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Phospholipase C gamma 2 is essential for specific functions of Fc epsilon R and Fc gamma R

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Wortmannin-sensitive phosphorylation, translocation, and activation of PLCgamma1, but not PLCgamma2, in antigen-stimulated RBL-2H3 mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Inhibition of Fc epsilon-RI-mediated activation of rat basophilic leukemia cells by Clostridium difficile toxin B (monoglucosyltransferase)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Activated Cdc42/Rac reconstitutes Fcepsilon RI-mediated Ca2+ mobilization and degranulation in mutant RBL mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Cdc42 and Rac stimulate exocytosis of secretory granules by activating the IP(3)/calcium pathway in RBL-2H3 mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Molecular modeling of the membrane targeting of phospholipase C pleckstrin homology domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Leukotriene D(4) triggers an association between gbetagamma subunits and phospholipase C-gamma1 in intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Interaction of elongation factor-1alpha and pleckstrin homology domain of phospholipase C-gamma 1 with activating its activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Phospholipase C-gamma is required for agonist-induced Ca2+ entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Phospholipase Cgamma1 controls surface expression of TRPC3 through an intermolecular PH domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Rapid vesicular translocation and insertion of TRP channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

B cells acquire antigen from target cells after synapse formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

LFA-1/ICAM-1 interaction lowers the threshold of B cell activation by facilitating B cell adhesion and synapse formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Lipid rafts and B-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Integrin signaling to the actin cytoskeleton.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Cell biology. Integrins, rafts, Rac, and Rho.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

Signal transduction through Vav-2 participates in humoral immune responses and B cell maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509396200

21 January 2018

Identifiers

DOI

10.1074/JBC.M509396200

1 reference

19 September 2017

1 reference