(Q40372985)

19 September 2017

title

Allosteric interaction between zinc and glutamate binding domains on NR2A causes desensitization of NMDA receptors (English)

1 reference

19 September 2017

1 reference

Kevin Erreger

1

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19 September 2017

Stephen F Traynelis

series ordinal

2

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19 September 2017

language of work or name

English

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publication date

15 September 2005

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19 September 2017

published in

Journal of Physiology

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19 September 2017

volume

569

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19 September 2017

issue

Pt 2

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19 September 2017

page(s)

381-393

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Visualization of transmitter release with zinc fluorescence detection at the mouse hippocampal mossy fibre synapse

19 September 2017

cites work

1 reference

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29 August 2018

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Modulation of triheteromeric NMDA receptors by N-terminal domain ligands

29 August 2018

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Subunit-specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles.

29 August 2018

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The micromolar zinc-binding domain on the NMDA receptor subunit NR2B.

29 August 2018

1 reference

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Protons trap NR1/NR2B NMDA receptors in a nonconducting state.

29 August 2018

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Differential effects on current kinetics by point mutations in the lurcher motif of NR1/NR2A receptors.

29 August 2018

1 reference

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Reaction mechanism determines NMDA receptor response to repetitive stimulation

29 August 2018

1 reference

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Site within N-Methyl-D-aspartate receptor pore modulates channel gating.

29 August 2018

1 reference

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ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

29 August 2018

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Evidence for chelatable zinc in the extracellular space of the hippocampus, but little evidence for synaptic release of Zn.

29 August 2018

1 reference

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Molecular determinants of proton-sensitive N-methyl-D-aspartate receptor gating.

29 August 2018

1 reference

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A site in the fourth membrane-associated domain of the N-methyl-D-aspartate receptor regulates desensitization and ion channel gating

29 August 2018

1 reference

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Mapping the binding site of the neuroprotectant ifenprodil on NMDA receptors.

29 August 2018

1 reference

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Calcineurin acts via the C-terminus of NR2A to modulate desensitization of NMDA receptors

29 August 2018

1 reference

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Exocytosed protons feedback to suppress the Ca2+ current in mammalian cone photoreceptors

29 August 2018

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Open probability of homomeric murine 5-HT3A serotonin receptors depends on subunit occupancy

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

Allosteric interaction between the amino terminal domain and the ligand binding domain of NR2A.

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

Molecular organization of a zinc binding n-terminal modulatory domain in a NMDA receptor subunit.

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

Molecular determinants of coordinated proton and zinc inhibition of N-methyl-D-aspartate NR1/NR2A receptors

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

Four residues of the extracellular N-terminal domain of the NR2A subunit control high-affinity Zn2+ binding to NMDA receptors

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

Identification and mechanism of action of two histidine residues underlying high-affinity Zn2+ inhibition of the NMDA receptor

29 August 2018

1 reference

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Phenylethanolamines inhibit NMDA receptors by enhancing proton inhibition

29 August 2018

1 reference

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Tyrosine kinase potentiates NMDA receptor currents by reducing tonic zinc inhibition

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

The glutamate receptor ion channels

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

Software-based correction of single compartment series resistance errors

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

An allosteric interaction between the NMDA receptor polyamine and ifenprodil sites in rat cultured cortical neurones

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

Glycine-independent NMDA receptor desensitization: localization of structural determinants

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

N-terminal domains in the NR2 subunit control desensitization of NMDA receptors

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

High-affinity zinc inhibition of NMDA NR1-NR2A receptors

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

Differential sensitivity of recombinant N-methyl-D-aspartate receptor subtypes to zinc inhibition

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

Influence of extracellular pH on inhibition by ifenprodil at N-methyl-D-aspartate receptors in Xenopus oocytes

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

Calcium-dependent inactivation of recombinant N-methyl-D-aspartate receptors is NR2 subunit specific.

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

Separating dual effects of zinc at recombinant N-methyl-D-aspartate receptors.

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

Changing subunit composition of heteromeric NMDA receptors during development of rat cortex

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

Molecular characterization of N-methyl-D-aspartate receptors expressed in mammalian cells yields evidence for the coexistence of three subunit types within a discrete receptor molecule

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

Calcium-induced actin depolymerization reduces NMDA channel activity

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

Inactivation of NMDA channels in cultured hippocampal neurons by intracellular calcium

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

Rapid extracellular pH transients related to synaptic transmission in rat hippocampal slices

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

Regulation of NMDA receptor desensitization in mouse hippocampal neurons by glycine.

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

Modulation of N-methyl-D-aspartic acid receptor desensitization by glycine in mouse cultured hippocampal neurones

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

The effect of agonist concentration, membrane voltage and calcium on N-methyl-D-aspartate receptor desensitization.

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

A kinetic analysis of the modulation of N-methyl-D-aspartic acid receptors by glycine in mouse cultured hippocampal neurones

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

Pharmacological properties and H+ sensitivity of excitatory amino acid receptor channels in rat cerebellar granule neurones

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

The time course of glutamate in the synaptic cleft

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

NMDA channel behavior depends on agonist affinity

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464251

Rundown of N-methyl-D-aspartate channels during whole-cell recording in rat hippocampal neurons: role of Ca2+ and ATP

29 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.095497

Regulation of glycine-insensitive desensitization of the NMDA receptor in outside-out patches

21 January 2018

1 reference

12 December 2020

Synaptic desensitization of NMDA receptors by calcineurin

1 reference

12 December 2020

Glycine-insensitive desensitization of NMDA responses in cultured mouse embryonic neurons

1 reference

12 December 2020

Activation and desensitization of N-methyl-D-aspartate receptors in nucleated outside-out patches from mouse neurones

1 reference

12 December 2020

10.1113/JPHYSIOL.2005.095497

Identifiers

DOI

1 reference

19 September 2017

0 references

1 reference