(Q40373481)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16162926%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

title

20-oxo-5beta-pregnan-3alpha-yl sulfate is a use-dependent NMDA receptor inhibitor (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16162926%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16162926%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

author name string

Milos Petrovic

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16162926%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Miloslav Sedlacek

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16162926%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Martin Horak

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16162926%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Hana Chodounska

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16162926%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

language of work or name

English

0 references

publication date

1 September 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16162926%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16162926%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

volume

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16162926%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

issue

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16162926%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

page(s)

8439-8450

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16162926%20AND%20SRC:MED&resulttype=core&format=json

The glutamate receptor ion channels

6 January 2020

cites work

1 reference

12 December 2020

The role of excitotoxicity in neurodegenerative disease: implications for therapy

1 reference

12 December 2020

Subtype-dependence of NMDA receptor channel open probability.

1 reference

12 December 2020

Distinct roles of synaptic and extrasynaptic NMDA receptors in excitotoxicity

1 reference

12 December 2020

Molecular and functional properties of synaptically activated NMDA receptors in neonatal motoneurons in rat spinal cord slices

1 reference

12 December 2020

Potential clinical uses of neuroactive steroids

1 reference

12 December 2020

Structural modifications to an N-methyl-D-aspartate receptor antagonist result in large differences in trapping block

1 reference

12 December 2020

Effects of steroids on NMDA receptors and excitatory synaptic transmission in neonatal motoneurons in rat spinal cord slices.

1 reference

12 December 2020

Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death

1 reference

12 December 2020

Intracellular domains of NR2 alter calcium-dependent inactivation of N-methyl-D-aspartate receptors.

1 reference

12 December 2020

Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids

1 reference

12 December 2020

NMDA receptor pathways as drug targets

1 reference

12 December 2020

Activation of NR1/NR2B NMDA receptors.

1 reference

12 December 2020

Synthesis, regulation, and function of neurosteroids

1 reference

12 December 2020

Modal gating of NMDA receptors and the shape of their synaptic response.

1 reference

12 December 2020

Brain neurosteroids are 4th generation neuromessengers in the brain: cell biophysical analysis of steroid signal transduction

1 reference

12 December 2020

High probability opening of NMDA receptor channels by L-glutamate

1 reference

12 December 2020

NMDA channel behavior depends on agonist affinity.

1 reference

12 December 2020

1 reference

12 December 2020

Heteromeric NMDA receptors: molecular and functional distinction of subtypes

1 reference

12 December 2020

The neuroactive steroid 3-alpha-ol-5-beta-pregnan-20-one hemisuccinate, a selective NMDA receptor antagonist improves behavioral performance following spinal cord ischemia

1 reference

12 December 2020

Synthesis of the sulfates derived from 5 alpha-cholestane-3 beta,6 alpha-diol

1 reference

12 December 2020

Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity

1 reference

12 December 2020

A steroid modulatory domain on NR2B controls N-methyl-D-aspartate receptor proton sensitivity

1 reference

12 December 2020

Molecular mechanism of pregnenolone sulfate action at NR1/NR2B receptors.

1 reference

12 December 2020

Identification of a neurosteroid binding site contained within the GluR2-S1S2 domain

1 reference

12 December 2020

Pregnenolone sulfate: a positive allosteric modulator at the N-methyl-D-aspartate receptor

1 reference

12 December 2020

Neuroprotective and symptomatological action of memantine relevant for Alzheimer's disease--a unified glutamatergic hypothesis on the mechanism of action.

1 reference

12 December 2020

Actions of ketamine, phencyclidine and MK-801 on NMDA receptor currents in cultured mouse hippocampal neurones

1 reference

12 December 2020

Modulation of N-methyl-D-aspartic acid receptor desensitization by glycine in mouse cultured hippocampal neurones

1 reference

12 December 2020

Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate

1 reference

12 December 2020

Use-dependent block of excitatory amino acid currents in cultured neurons by ketamine

1 reference

12 December 2020

Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels

1 reference

12 December 2020

Modulation of excitatory amino acid receptors by group IIB metal cations in cultured mouse hippocampal neurones

1 reference

12 December 2020

Ionic Blockage of Sodium Channels in Nerve

1 reference

12 December 2020

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1 reference

12 December 2020

The charge carried by single-channel currents of rat cultured muscle cells in the presence of local anaesthetics.

1 reference

12 December 2020

Therapeutic potential of excitatory amino acid antagonists: channel blockers and 2,3-benzodiazepines

1 reference

12 December 2020

Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

1 reference

12 December 2020

3 alpha-Hydroxy-5 beta-pregnan-20-one sulfate: a negative modulator of the NMDA-induced current in cultured neurons.

1 reference

12 December 2020

Ligand affinities at recombinant N-methyl-D-aspartate receptors depend on subunit composition

1 reference

12 December 2020

Trapping of glutamate and glycine during open channel block of rat hippocampal neuron NMDA receptors by 9-aminoacridine.

1 reference

12 December 2020

Zinc potentiates agonist-induced currents at certain splice variants of the NMDA receptor.

1 reference

12 December 2020

Pregnenolone sulfate potentiation of N-methyl-D-aspartate receptor channels in hippocampal neurons.

1 reference

12 December 2020

Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors.

1 reference

12 December 2020

Regulation of glycine-insensitive desensitization of the NMDA receptor in outside-out patches

1 reference

12 December 2020

Mutational analysis of the glycine-binding site of the NMDA receptor: structural similarity with bacterial amino acid-binding proteins

1 reference

12 December 2020

GEPASI: a software package for modelling the dynamics, steady states and control of biochemical and other systems

1 reference

12 December 2020

Patch-clamp recordings from the soma and dendrites of neurons in brain slices using infrared video microscopy

1 reference

12 December 2020

A synaptic model of memory: long-term potentiation in the hippocampus

1 reference

12 December 2020

Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits

1 reference

12 December 2020

NR2A subunit expression shortens NMDA receptor synaptic currents in developing neocortex.

1 reference

12 December 2020

Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit

1 reference

12 December 2020

Biochemistry by numbers: simulation of biochemical pathways with Gepasi 3

1 reference

12 December 2020

Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors

1 reference

12 December 2020

N-terminal domains in the NR2 subunit control desensitization of NMDA receptors

1 reference

12 December 2020

Evidence for a tetrameric structure of recombinant NMDA receptors.

1 reference

12 December 2020

Pregnenolone sulfate exacerbates NMDA-induced death of hippocampal neurons.

1 reference

12 December 2020

Non-linear optimization of biochemical pathways: applications to metabolic engineering and parameter estimation

1 reference

12 December 2020

10.1523/JNEUROSCI.1407-05.2005

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16162926%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16162926%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

PubMed publication ID

16162926

1 reference