(Q48491954)

English

Neuroprotective and symptomatological action of memantine relevant for Alzheimer's disease--a unified glutamatergic hypothesis on the mechanism of action.

scientific article published in January 2000

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scholarly article

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/16787834

Neuroprotective and symptomatological action of memantine relevant for Alzheimer's disease--a unified glutamatergic hypothesis on the mechanism of action. (English)

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/16787834

Alzheimer's disease

0 references

Wojciech Danysz

1

object named as

W Danysz

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/16787834

author name string

C G Parsons

2

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/16787834

H J Mobius

3

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/16787834

A Stoffler

4

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/16787834

G Quack

5

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/16787834

publication date

1 January 2000

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/16787834

Neurotoxicity Research

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/16787834

2

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/16787834

2-3

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Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/16787834

85-97

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Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/16787834

https://scigraph.springernature.com/pub.10.1007/bf03033787

0 references

Effects of memantine and MK-801 on NMDA-induced currents in cultured neurones and on synaptic transmission and LTP in area CA1 of rat hippocampal slices

1 reference

https://api.crossref.org/works/10.1007%2FBF03033787

21 January 2018

Risk factors in Alzheimer's disease: a clinicopathologic study

1 reference

https://api.crossref.org/works/10.1007%2FBF03033787

21 January 2018

Modifications of neuronal phosphorylated tau immunoreactivity induced by NMDA toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of glutamate antagonists in continuous multiple-trial and single-trial dark avoidance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Ca2+ influx induced by beta-amyloid peptide 25-35 in cultured hippocampal neurons results from network excitation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contributory mechanisms in the causation of neurodegenerative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid selectively augments NMDA receptor-mediated synaptic transmission in rat hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of tau neuronal expression induced by NMDA, non-NMDA and metabotropic glutamate receptor agonists.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low concentrations of N-methyl-D-aspartate inhibit the induction of long-term potentiation in rat hippocampal slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase dependent DNA fragmentation might be associated with excitotoxicity in Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid appearance of beta-amyloid precursor protein immunoreactivity in glial cells following excitotoxic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of ischemia on the in vivo release of striatal dopamine, glutamate, and gamma-aminobutyric acid studied by intracerebral microdialysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta peptide (25-35) inhibits Na+-dependent glutamate uptake in rat hippocampal astrocyte cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Investigations of neurotoxicity and neuroprotection within the nucleus basalis of the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excitatory amino acid receptors and synaptic plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is the neuronal basis of Alzheimer's disease cholinergic or glutamatergic?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective strategies for treatment of lesions produced by mitochondrial toxins: implications for neurodegenerative diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid produces a delayed NMDA receptor-dependent reduction in synaptic transmission in rat hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Memantine in the treatment of mild to moderate dementia syndrome. A double-blind placebo-controlled study

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative autoradiographic distribution of L-[3H]glutamate-binding sites in rat central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Head trauma as a risk factor for Alzheimer's disease: a collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amino-alkyl-cyclohexanes are novel uncompetitive NMDA receptor antagonists with strong voltage-dependency and fast blocking kinetics: in vitro and in vivo characterization.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Staging of Alzheimer-related cortical destruction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of NMDA-receptor antagonists on long-term potentiation and hypoxic/hypoglycaemic excitotoxicity in hippocampal slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and tolerability of memantine in patients with dementia syndrome. A double-blind, placebo controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Learning deficits induced by chronic intraventricular infusion of quinolinic acid--protection by MK-801 and memantine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of mitochondrial failure upon cholinergic toxicity in the nucleus basalis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patch clamp studies on the kinetics and selectivity of N-methyl-D-aspartate receptor antagonism by memantine (1-amino-3,5-dimethyladamantan).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebrospinal fluid and serum concentrations of the N-methyl-D-aspartate (NMDA) receptor antagonist memantine in man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate release from microglia via glutamate transporter is enhanced by amyloid-beta peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Memantine restores long term potentiation impaired by tonic N-methyl-D-aspartate (NMDA) receptor activation following reduction of Mg2+ in hippocampal slices.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Memantine in severe dementia: results of the 9M-Best Study (Benefit and efficacy in severely demented patients during treatment with memantine).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA antagonist blockade of AT8 tau immunoreactive changes in neuronal cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiglutamatergic therapy in Alzheimer's disease--effects of lamotrigine. Short communication.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist--a review of preclinical data

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low-frequency activation of the NMDA receptor system can prevent the induction of LTP

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglial release of nitric oxide by the synergistic action of beta-amyloid and IFN-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MK-801, memantine and amantadine show neuroprotective activity in the nucleus basalis magnocellularis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Magnesium gates glutamate-activated channels in mouse central neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cortical pyramidal neurone loss may cause glutamatergic hypoactivity and cognitive impairment in Alzheimer's disease: investigative and therapeutic perspectives

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of learning processes by ionotropic glutamate receptor ligands.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aminoadamantanes as NMDA receptor antagonists and antiparkinsonian agents--preclinical studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid peptide fragment 25-35 potentiates the calcium-dependent release of excitatory amino acids from depolarized hippocampal slices.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glumate receptor dysfunction and Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain penetration and in vivo recovery of NMDA receptor antagonists amantadine and memantine: a quantitative microdialysis study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative patch-clamp studies with freshly dissociated rat hippocampal and striatal neurons on the NMDA receptor antagonistic effects of amantadine and memantine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Senile plaques stimulate microglia to release a neurotoxin found in Alzheimer brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium: still center-stage in hypoxic-ischemic neuronal death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Glutamate-induced Neurotoxicity by a Tau Antisense Oligonucleotide in Primary Culture of Rat Cerebellar Granule Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uncompetitive NMDA receptor antagonists attenuate NMDA-induced impairment of passive avoidance learning and LTP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the potency, kinetics and voltage-dependency of a series of uncompetitive NMDA receptor antagonists in vitro with anticonvulsive and motor impairment activity in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amantadine and memantine are NMDA receptor antagonists with neuroprotective properties.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-amyloid protein enhances macrophage production of oxygen free radicals and glutamate

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of beta-amyloid-(25-35) peptides on radioligand binding to excitatory amino acid receptors and voltage-dependent calcium channels: evidence for a selective affinity for the glutamate and glycine recognition sites of the NMDA receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate transporter alterations in Alzheimer disease are possibly associated with abnormal APP expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The time course of glutamate in the synaptic cleft

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate in CNS disorders as a target for drug development: an update

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16787834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF03033787

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/16787834

release_7a467txnfvggnlsm2ci3pgmtxm

1 reference

https://api.fatcat.wiki/v0/release/7a467txnfvggnlsm2ci3pgmtxm

24 November 2022

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mapped directly with Wikidata item

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/16787834

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