(Q40379554)

English

The position of premature termination codons in the hepatocyte nuclear factor -1 beta gene determines susceptibility to nonsense-mediated decay

scientific article published on 15 November 2005

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scholarly article

1 reference

Europe PubMed Central

20 September 2017

The position of premature termination codons in the hepatocyte nuclear factor -1 beta gene determines susceptibility to nonsense-mediated decay (English)

1 reference

Europe PubMed Central

20 September 2017

object named as

Sian Ellard

5

0 references

Christine Bellanné-Chantelot

3

object named as

Christine Bellanne-Chantelot

1 reference

Europe PubMed Central

20 September 2017

author name string

L W Harries

1

1 reference

Europe PubMed Central

20 September 2017

Coralie Bingham

2

1 reference

Europe PubMed Central

20 September 2017

A T Hattersley

4

1 reference

Europe PubMed Central

20 September 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

15 November 2005

1 reference

Europe PubMed Central

20 September 2017

1 reference

Europe PubMed Central

20 September 2017

118

1 reference

Europe PubMed Central

20 September 2017

214-224

1 reference

Europe PubMed Central

20 September 2017

2

1 reference

Europe PubMed Central

20 September 2017

https://scigraph.springernature.com/pub.10.1007/s00439-005-0023-y

0 references

Clinical spectrum associated with hepatocyte nuclear factor-1beta mutations.

1 reference

https://api.crossref.org/works/10.1007%2FS00439-005-0023-Y

21 January 2018

Infrequent translation of a nonsense codon is sufficient to decrease mRNA level

1 reference

https://api.crossref.org/works/10.1007%2FS00439-005-0023-Y

21 January 2018

Killing the messenger: new insights into nonsense-mediated mRNA decay

1 reference

https://api.crossref.org/works/10.1007%2FS00439-005-0023-Y

21 January 2018

Introns are cis effectors of the nonsense-codon-mediated reduction in nuclear mRNA abundance

1 reference

https://api.crossref.org/works/10.1007%2FS00439-005-0023-Y

21 January 2018

Genetic evidence that HNF-1alpha-dependent transcriptional control of HNF-4alpha is essential for human pancreatic beta cell function

1 reference

https://api.crossref.org/works/10.1007%2FS00439-005-0023-Y

21 January 2018

Context effects and inefficient initiation at non-AUG codons in eucaryotic cell-free translation systems

1 reference

https://api.crossref.org/works/10.1007%2FS00439-005-0023-Y

21 January 2018

At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA: a possible link between nuclear splicing and cytoplasmic translation

1 reference

https://api.crossref.org/works/10.1007%2FS00439-005-0023-Y

21 January 2018

The human intronless melanocortin 4-receptor gene is NMD insensitive

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence to implicate translation by ribosomes in the mechanism by which nonsense codons reduce the nuclear level of human triosephosphate isomerase mRNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An activated 5' cryptic splice site in the human ALG3 gene generates a premature termination codon insensitive to nonsense-mediated mRNA decay in a new case of congenital disorder of glycosylation type Id (CDG-Id)

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Solitary functioning kidney and diverse genital tract malformations associated with hepatocyte nuclear factor-1beta mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nonsense-mediated mRNA decay pathway triggers degradation of most BRCA1 mRNAs bearing premature termination codons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

mRNA quality control: Marking the message for life or death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Premature termination mutations in FBN1: distinct effects on differential allelic expression and on protein and clinical phenotypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal splicing of hepatocyte nuclear factor-1 beta in the renal cysts and diabetes syndrome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Severe hyperglycemia after renal transplantation in a pediatric patient with a mutation of the hepatocyte nuclear factor-1beta gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression patterns of vHNF1 and HNF1 homeoproteins in early postimplantation embryos suggest distinct and sequential developmental roles

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functions of HNF1 family members in differentiation of the visceral endoderm cell lineage

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Boundary-independent polar nonsense-mediated decay

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Four novel FBN1 mutations: significance for mutant transcript level and EGF-like domain calcium binding in the pathogenesis of Marfan syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the hepatocyte nuclear factor-1beta gene are associated with familial hypoplastic glomerulocystic kidney disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonsense-mediated mRNA decay in health and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Messenger RNA transcripts of the hepatocyte nuclear factor-1alpha gene containing premature termination codons are subject to nonsense-mediated decay

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the human genes encoding the transcription factors of the hepatocyte nuclear factor (HNF)1 and HNF4 families: functional and pathological consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Congenital afibrinogenemia: mutations leading to premature termination codons in fibrinogen Aalpha -chain gene are not associated with the decay of the mutant mRNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mutated human gene encoding hepatocyte nuclear factor 1beta inhibits kidney formation in developing Xenopus embryos

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A splicing-dependent regulatory mechanism that detects translation signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hnf6 and Tcf2 (MODY5) are linked in a gene network operating in a precursor cell domain of the embryonic pancreas

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct molecular and morphogenetic properties of mutations in the human HNF1beta gene that lead to defective kidney development

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

De novo HNF-1 beta gene mutation in familial hypoplastic glomerulocystic kidney disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanism for distinct neurological phenotypes conveyed by allelic truncating mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal cysts and diabetes syndrome resulting from mutations in hepatocyte nuclear factor-1beta.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An unappreciated role for RNA surveillance

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal nephron development associated with a frameshift mutation in the transcription factor hepatocyte nuclear factor-1 beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Listening to silence and understanding nonsense: exonic mutations that affect splicing

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the vHNF1/HNF1beta homeoprotein gene during mouse organogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mechanism for exon skipping caused by nonsense or missense mutations in BRCA1 and other genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organization and partial sequence of the hepatocyte nuclear factor-4 alpha/MODY1 gene and identification of a missense mutation, R127W, in a Japanese family with MODY

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neonatal Diabetes Mellitus and Neonatal Polycystic, Dysplastic Kidneys: Phenotypically Discordant Recurrence of a Mutation in the Hepatocyte Nuclear Factor-1β Gene Due to Germline Mosaicism

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The scanning model for translation: an update

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal splicing of hepatocyte nuclear factor 1 alpha in maturity-onset diabetes of the young.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

More potent transcriptional activators or a transdominant inhibitor of the HNF1 homeoprotein family are generated by alternative RNA processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a gain-of-function mutation in the HNF-1beta gene in a Japanese family with MODY.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Promoter-specific repression of hepatocyte nuclear factor (HNF)-1 beta and HNF-1 alpha transcriptional activity by an HNF-1 beta missense mutant associated with Type 5 maturity-onset diabetes of the young with hepatic and biliary manifestations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonsense mutations in close proximity to the initiation codon fail to trigger full nonsense-mediated mRNA decay.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatocyte nuclear factor 4 alpha isoforms originated from the P1 promoter are expressed in human pancreatic beta-cells and exhibit stronger transcriptional potentials than P2 promoter-driven isoforms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

vHNF1 is expressed in epithelial cells of distinct embryonic origin during development and precedes HNF1 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonsense-associated altered splicing: a frame-dependent response distinct from nonsense-mediated decay

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatocyte nuclear factor-1 alpha (HNF-1 alpha) and HNF-1 beta regulate transcription via two elements in an intestine-specific promoter.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HNF-1 alpha and HNF-1 beta (vHNF-1) share dimerization and homeo domains, but not activation domains, and form heterodimers in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a new case of hepatocyte nuclear factor-1beta mutation with highly varied phenotypes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contrasting diabetes phenotypes associated with hepatocyte nuclear factor-1alpha and -1beta mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that translation reinitiation abrogates nonsense-mediated mRNA decay in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A frameshifting mutation in CHRNE unmasks skipping of the preceding exon

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient downregulation of immunoglobulin mu mRNA with premature translation-termination codons requires the 5'-half of the VDJ exon

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133182

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00439-005-0023-Y

1 reference

Europe PubMed Central

20 September 2017

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0 references

1 reference

Europe PubMed Central

20 September 2017

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