(Q40379661)

20 September 2017

title

Okadaic acid induces tyrosine phosphorylation of IkappaBalpha that mediated by PKR pathway in human osteoblastic MG63 cells (English)

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20 September 2017

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Hiroyuki Morimoto

1

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20 September 2017

Akiko Ozaki

2

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20 September 2017

Hirohiko Okamura

3

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20 September 2017

Kaya Yoshida

4

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20 September 2017

Seiichiro Kitamura

5

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20 September 2017

Tatsuji Haneji

6

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20 September 2017

publication date

1 August 2005

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Molecular and Cellular Biochemistry

20 September 2017

published in

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20 September 2017

volume

276

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20 September 2017

issue

1-2

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20 September 2017

page(s)

211-217

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Okadaic acid, useful tool for studying cellular processes

20 September 2017

cites work

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https://api.crossref.org/works/10.1007%2FS11010-005-4440-Y

Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-005-4440-Y

Okadaic acid induces apoptosis through double-stranded RNA-dependent protein kinase/eukaryotic initiation factor-2alpha pathway in human osteoblastic MG63 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-005-4440-Y

Direct inhibition of NF-kappa B blocks bone erosion associated with inflammatory arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-005-4440-Y

The protein phosphatase inhibitors, okadaic acid and calyculin A, induce apoptosis in human submandibular gland ductal cell line HSG cells

21 January 2018

1 reference

12 December 2020

PKR stimulates NF-kappaB irrespective of its kinase function by interacting with the IkappaB kinase complex.

1 reference

12 December 2020

Okadaic acid stimulates expression of Fas receptor and Fas ligand by activation of nuclear factor kappa-B in human oral squamous carcinoma cells

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12 December 2020

The protein kinase PKR: a molecular clock that sequentially activates survival and death programs

1 reference

12 December 2020

Control of apoptosis by Rel/NF-kappaB transcription factors

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12 December 2020

Cleavage of nucleolin and argyrophilic nucleolar organizer region associated proteins in apoptosis-induced cells

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12 December 2020

TAT fusion proteins containing tyrosine 42-deleted IkappaBalpha arrest osteoclastogenesis

1 reference

12 December 2020

Rel/NF-kappa B/I kappa B signal transduction in the generation and treatment of human cancer

1 reference

12 December 2020

TRAF family proteins link PKR with NF-kappa B activation

1 reference

12 December 2020

Inhibitors of protein synthesis and RNA synthesis protect against okadaic acid-induced apoptosis in human osteosarcoma cell line MG63 cells but not in Saos-2 cells

1 reference

12 December 2020

Induction of Oxidative Stress by Okadaic Acid Is Required for Activation of Transcription Factor NF-κB

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12 December 2020

Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha

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12 December 2020

Stimulation of interleukin-8 production by okadaic acid and vanadate in a human promyelocyte cell line, an HL-60 subline. Possible role of mitogen-activated protein kinase on the okadaic acid-induced NF-kappaB activation

1 reference

12 December 2020

The eIF-2alpha kinases and the control of protein synthesis

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12 December 2020

The direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein kinase is necessary but not sufficient for inactivation and disruption of enzyme dimer formation

1 reference

12 December 2020

Phosphorylation of the RNA-dependent protein kinase regulates its RNA-binding activity

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12 December 2020

Okadaic acid stimulates apoptosis through expression of Fas receptor and Fas ligand in human oral squamous carcinoma cells

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12 December 2020

Activators and target genes of Rel/NF-kappaB transcription factors

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12 December 2020

Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation of p65: evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinase

1 reference

12 December 2020

Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

1 reference

12 December 2020

An essential role for the interferon-inducible, double-stranded RNA-activated protein kinase PKR in the tumor necrosis factor-induced apoptosis in U937 cells

1 reference

12 December 2020

Transcription factor NF-Y regulates mdr1 expression through binding to inverted CCAAT sequence in drug-resistant human squamous carcinoma cells

1 reference

12 December 2020

Double-stranded RNA-activated protein kinase mediates virus-induced apoptosis: a new role for an old actor

1 reference

12 December 2020

The interferon-induced double-stranded RNA-activated protein kinase PKR will phosphorylate serine, threonine, or tyrosine at residue 51 in eukaryotic initiation factor 2alpha

1 reference

12 December 2020

Possible involvement of double-stranded RNA-activated protein kinase in cell death by influenza virus infection.

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12 December 2020

PKR; a sentinel kinase for cellular stress

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12 December 2020

Translation inhibition in apoptosis: caspase-dependent PKR activation and eIF2-alpha phosphorylation

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12 December 2020

Ischemia/reperfusion injury in the liver of BALB/c mice activates AP-1 and nuclear factor kappaB independently of IkappaB degradation

1 reference

12 December 2020

The protein phosphatase inhibitors okadaic acid and calyculin A induce apoptosis in human osteoblastic cells

1 reference

12 December 2020

Tyrosine phosphorylation of I kappa B alpha activates NF kappa B through a redox-regulated and c-Src-dependent mechanism following hypoxia/reoxygenation.

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12 December 2020

Tyrosine phosphorylation-dependent activation of NF-kappa B. Requirement for p56 LCK and ZAP-70 protein tyrosine kinases

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12 December 2020

Induction of apoptosis in human oral squamous carcinoma cell lines by protein phosphatase inhibitors

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12 December 2020

NF-kappaB at the crossroads of life and death

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12 December 2020

Tumor necrosis factor-alpha activation of nuclear transcription factor-kappaB in marrow macrophages is mediated by c-Src tyrosine phosphorylation of Ikappa Balpha.

1 reference

12 December 2020

A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis

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12 December 2020

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

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12 December 2020

A type 1 phosphoprotein phosphatase active with phosphorylated Mr = 68,000 initiation factor 2 kinase

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12 December 2020

Okadaic acid induces sustained activation of NFkappaB and degradation of the nuclear IkappaBalpha in human neutrophils

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12 December 2020

Activation of the I kappa B alpha kinase (IKK) complex by double-stranded RNA-binding defective and catalytic inactive mutants of the interferon-inducible protein kinase PKR.

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12 December 2020

Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): mechanism of action

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12 December 2020

Activation of NF-kappaB in cells productively infected with HSV-1 depends on activated protein kinase R and plays no apparent role in blocking apoptosis

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12 December 2020

PKR, apoptosis and cancer

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12 December 2020

10.1007/S11010-005-4440-Y

Identifiers

DOI

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20 September 2017

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