(Q40386167)

20 September 2017

title

Role of aspartate 298 in mouse 5-HT3A receptor gating and modulation by extracellular Ca2+. (English)

1 reference

20 September 2017

Xiang-Qun Hu

1

1 reference

20 September 2017

David M Lovinger

series ordinal

2

1 reference

20 September 2017

language of work or name

English

0 references

publication date

11 August 2005

1 reference

20 September 2017

published in

Journal of Physiology

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20 September 2017

volume

568

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20 September 2017

issue

Pt 2

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20 September 2017

page(s)

381-396

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Role of charged residues in coupling ligand binding and channel activation in the extracellular domain of the glycine receptor.

20 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Desensitization of mouse nicotinic acetylcholine receptor channels. A two-gate mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

GABA(A) receptor M2-M3 loop secondary structure and changes in accessibility during channel gating.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Changes in [Ca2+]0 during anoxia in CNS white matter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Ion permeation and conduction in a human recombinant 5-HT3 receptor subunit (h5-HT3A).

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

A single residue in the M2-M3 loop is a major determinant of coupling between binding and gating in neuronal nicotinic receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

A novel hyperekplexia-causing mutation in the pre-transmembrane segment 1 of the human glycine receptor alpha1 subunit reduces membrane expression and impairs gating by agonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

A novel class of ligand-gated ion channel is activated by Zn2+

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Calcium dynamics in the extracellular space of mammalian neural tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

An electrophysiological investigation of the properties of a murine recombinant 5-HT3 receptor stably expressed in HEK 293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

The extracellular linker of muscle acetylcholine receptor channels is a gating control element

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Arginine 222 in the pre-transmembrane domain 1 of 5-HT3A receptors links agonist binding to channel gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Desensitized states prolong GABAA channel responses to brief agonist pulses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Emerging structure of the nicotinic acetylcholine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Coupling of agonist binding to channel gating in the GABA(A) receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Properties of human glycine receptors containing the hyperekplexia mutation alpha1(K276E), expressed in Xenopus oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

The role of the agonist binding site in Ca(2+) inhibition of the recombinant 5-HT(3A) receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Evolutionary history of the ligand-gated ion-channel superfamily of receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Arg-274 and Leu-277 of the gamma-aminobutyric acid type A receptor alpha 2 subunit define agonist efficacy and potency

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Mutation of an arginine residue in the human glycine receptor transforms beta-alanine and taurine from agonists into competitive antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Structural and electrostatic properties of the 5-HT3 receptor pore revealed by substituted cysteine accessibility mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

The molecular basis of the structure and function of the 5-HT3 receptor: a model ligand-gated ion channel (review)

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

A residue in the middle of the M2-M3 loop of the beta4 subunit specifically affects gating of neuronal nicotinic receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Extracellular Ca2+ depletion contributes to fast activity-dependent modulation of synaptic transmission in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Structure and action of the nicotinic acetylcholine receptor explored by electron microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Selection of distinct conformational states of the 5-HT3 receptor by full and partial agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Ca2+ ions block and permeate serotonin 5-HT3 receptor channels in rat hippocampal interneurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Assessment of frequency-dependent alterations in the level of extracellular Ca2+ in the synaptic cleft

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Alcohols potentiate the function of 5-HT3 receptor-channels on NCB-20 neuroblastoma cells by favouring and stabilizing the open channel state

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

Structure and gating mechanism of the acetylcholine receptor pore

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474733

DRPEER: a motif in the extracellular vestibule conferring high Ca2+ flux rates in NMDA receptor channels.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474733

Coupled and uncoupled gating and desensitization effects by pore domain mutations in GABA(A) receptors.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474733

Agonist Trapping by GABAA Receptor Channels.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474733

The surface accessibility of the glycine receptor M2-M3 loop is increased in the channel open state.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474733

A single amino-acid in the TM1 domain is an important determinant of the desensitization kinetics of recombinant human and guinea pig alpha-homomeric 5-hydroxytryptamine type 3 receptors

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474733

Gating of alpha3beta4 neuronal nicotinic receptor can be controlled by the loop M2-M3 of both alpha3 and beta4 subunits

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474733

Substitutions of the highly conserved M2 leucine create spontaneously opening rho1 gamma-aminobutyric acid receptors.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474733

Hippocampal interneurons are excited via serotonin-gated ion channels.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474733

Mutation of an aspartate residue highly conserved among G-protein-coupled receptors results in nonreciprocal disruption of alpha 2-adrenergic receptor-G-protein interactions. A negative charge at amino acid residue 79 forecasts alpha 2A-adrenergic r

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474733

Decreased agonist affinity and chloride conductance of mutant glycine receptors associated with human hereditary hyperekplexia

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474733

Ionic changes and alterations in the size of the extracellular space during epileptic activity

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474733

Stimulus- and amino acid-induced calcium and potassium changes in rat neocortex

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474733

Acetylcholine receptor channel imaged in the open state

4 November 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2005.092866

The channel opening rate of adult- and fetal-type mouse muscle nicotinic receptors activated by acetylcholine

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16096341

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A novel extracellular calcium sensing mechanism in voltage-gated potassium ion channels

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16096341

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Divalent cations modulate 5-HT3 receptor-induced currents in N1E-115 neuroblastoma cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16096341

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1113/JPHYSIOL.2005.092866

1 reference

20 September 2017

0 references

1 reference