(Q40391550)

20 September 2017

title

Mechanism of HIF-1alpha-dependent suppression of hypoxia-induced apoptosis in squamous cell carcinoma cells (English)

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20 September 2017

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squamous cell carcinoma

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Eri Sasabe

1

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20 September 2017

Yukihiro Tatemoto

2

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20 September 2017

Dechao Li

3

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20 September 2017

Tetsuya Yamamoto

4

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20 September 2017

Tokio Osaki

5

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20 September 2017

publication date

1 July 2005

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20 September 2017

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20 September 2017

volume

96

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20 September 2017

issue

7

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20 September 2017

page(s)

394-402

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Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

20 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00065.X

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00065.X

Hypoxia-inducible factor 1alpha protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00065.X

Oncogenic alterations of metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00065.X

Expression of hypoxia-inducible factor 1: mechanisms and consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00065.X

Targeting gene expression to hypoxic tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00065.X

Angiogenesis: how a tumor adapts to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00065.X

Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00065.X

The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00065.X

Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00065.X

Bcl-2-family proteins and the role of mitochondria in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00065.X

Control of mitochondrial permeability by Bcl-2 family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00065.X

Bcl-2 family members as sentinels of cellular integrity and role of mitochondrial intermembrane space proteins in apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00065.X

Akt regulates cell survival and apoptosis at a postmitochondrial level

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00065.X

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00065.X

p53- and p21-independent apoptosis of squamous cell carcinoma cells induced by 5-fluorouracil and radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00065.X

Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00065.X

The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00065.X

ERK activation upon hypoxia: involvement in HIF-1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00065.X

Transduction pathways involved in Hypoxia-Inducible Factor-1 phosphorylation and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00065.X

Tyrosine kinase receptor-activated signal transduction pathways which lead to oncogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00065.X

10.1111/J.1349-7006.2005.00065.X

21 January 2018

Identifiers

DOI

1 reference

release_frz54qy4gbhzbalkahwbweuwwa

20 September 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/frz54qy4gbhzbalkahwbweuwwa

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference