(Q34390790)

1 August 2017

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title

Transduction pathways involved in Hypoxia-Inducible Factor-1 phosphorylation and activation (English)

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1 August 2017

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Minet E

1

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1 August 2017

Michel G

2

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1 August 2017

Mottet D

3

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1 August 2017

Raes M

4

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1 August 2017

Michiels C

5

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1 August 2017

language of work or name

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1 October 2001

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Free Radical Biology and Medicine

1 August 2017

published in

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1 August 2017

volume

31

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1 August 2017

issue

7

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1 August 2017

page(s)

847-855

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Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

1 August 2017

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HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

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Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

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Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

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Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1

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Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

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7 January 2021

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

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Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway

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Hypoxia-induced activation of HIF-1: role of HIF-1alpha-Hsp90 interaction

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Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha

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A redox mechanism controls differential DNA binding activities of hypoxia-inducible factor (HIF) 1alpha and the HIF-like factor.

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Complex role of protein phosphorylation in gene activation by hypoxia

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Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity

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7 January 2021

Selective activation of p38alpha and p38gamma by hypoxia. Role in regulation of cyclin D1 by hypoxia in PC12 cells

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EPAS1 trans-activation during hypoxia requires p42/p44 MAPK

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Regulation of tyrosine hydroxylase gene expression during hypoxia: role of Ca2+ and PKC.

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L-type Ca(2+) channel activation regulates induction of c-fos transcription by hypoxia

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Hypoxia differentially regulates the mitogen- and stress-activated protein kinases. Role of Ca2+/CaM in the activation of MAPK and p38 gamma

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Hypoxia-induced protein binding to O2-responsive sequences on the tyrosine hydroxylase gene

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7 January 2021

Hypoxia induces c-fos transcription via a mitogen-activated protein kinase-dependent pathway

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7 January 2021

Hypoxic Stimulation of the Stress-activated Protein Kinases in Pulmonary Artery Fibroblasts

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7 January 2021

ERK activation upon hypoxia: involvement in HIF-1 activation

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Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation

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Hypoxia-induced bFGF gene expression is mediated through the JNK signal transduction pathway.

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7 January 2021

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

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Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

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Reactive oxygen species mediate the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells

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7 January 2021

p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

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7 January 2021

Endothelial cell responses to hypoxia: initiation of a cascade of cellular interactions

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7 January 2021

Hydrogen peroxide activates p70(S6k) signaling pathway

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7 January 2021

Release of hydrogen peroxide in response to hypoxia-reoxygenation: role of an NAD(P)H oxidase-like enzyme in endothelial cell plasma membrane

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Surviving ischemia: adaptive responses mediated by hypoxia-inducible factor 1

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7 January 2021

Inactivation of the PTEN tumor suppressor gene is associated with increased angiogenesis in clinically localized prostate carcinoma

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7 January 2021

Regulation of glut1 mRNA by hypoxia-inducible factor-1. Interaction between H-ras and hypoxia

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7 January 2021

Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha

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7 January 2021

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

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7 January 2021

Hypoxia-inducible factor-1alpha mediates hypoxia-induced delayed neuronal death that involves p53.

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7 January 2021

HIF-1alpha and p53 promote hypoxia-induced delayed neuronal death in models of CNS ischemia.

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7 January 2021

Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia

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7 January 2021

Hypoxia-induced VEGF enhances tumor survivability via suppression of serum deprivation-induced apoptosis

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7 January 2021

Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, [...]

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7 January 2021

10.1016/S0891-5849(01)00657-8

Identifiers

DOI

1 reference

1 August 2017

1 reference