(Q40407821)

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Live-attenuated intranasal parainfluenza virus type 2 vaccine candidates developed by reverse genetics containing L polymerase protein mutations imported from heterologous paramyxoviruses

scientific article published on September 2005

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Live-attenuated intranasal parainfluenza virus type 2 vaccine candidates developed by reverse genetics containing L polymerase protein mutations imported from heterologous paramyxoviruses (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

travel-associated infection

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attenuated vaccine

1 reference

based on heuristic

inferred from title

Brian R. Murphy

5

object named as

Brian R Murphy

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Europe PubMed Central

PubMed publication ID

20 September 2017

author name string

Sheila M Nolan

1

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Europe PubMed Central

PubMed publication ID

20 September 2017

Sonja R Surman

2

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Europe PubMed Central

PubMed publication ID

20 September 2017

Emerito Amaro-Carambot

3

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Europe PubMed Central

PubMed publication ID

20 September 2017

Peter L Collins

4

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Europe PubMed Central

PubMed publication ID

20 September 2017

Mario H Skiadopoulos

6

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Europe PubMed Central

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20 September 2017

language of work or name

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publication date

1 September 2005

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Europe PubMed Central

PubMed publication ID

20 September 2017

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Europe PubMed Central

PubMed publication ID

20 September 2017

23

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Europe PubMed Central

PubMed publication ID

20 September 2017

39

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Europe PubMed Central

PubMed publication ID

20 September 2017

4765-4774

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Respiratory syncytial virus: reverse genetics and vaccine strategies

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Attenuation of the recombinant human parainfluenza virus type 3 cp45 candidate vaccine virus is augmented by importation of the respiratory syncytial virus cpts530 L polymerase mutation

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The genome length of human parainfluenza virus type 2 follows the rule of six, and recombinant viruses recovered from non-polyhexameric-length antigenomic cDNAs contain a biased distribution of correcting mutations

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Live-attenuated virus vaccines for respiratory syncytial and parainfluenza viruses: applications of reverse genetics

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Generation of recombinant human parainfluenza virus type 1 vaccine candidates by importation of temperature-sensitive and attenuating mutations from heterologous paramyxoviruses

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Codon substitution mutations at two positions in the L polymerase protein of human parainfluenza virus type 1 yield viruses with a spectrum of attenuation in vivo and increased phenotypic stability in vitro

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A live attenuated recombinant chimeric parainfluenza virus (PIV) candidate vaccine containing the hemagglutinin-neuraminidase and fusion glycoproteins of PIV1 and the remaining proteins from PIV3 induces resistance to PIV1 even in animals immune to

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Cold-passaged human parainfluenza type 3 viruses contain ts and non-ts mutations leading to attenuation in rhesus monkeys

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Recombinant measles viruses expressing altered hemagglutinin (H) genes: functional separation of mutations determining H antibody escape from neurovirulence

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Sequence analysis of the Washington/1964 strain of human parainfluenza virus type 1 (HPIV1) and recovery and characterization of wild-type recombinant HPIV1 produced by reverse genetics

1 reference

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7 January 2021

Generation of a parainfluenza virus type 1 vaccine candidate by replacing the HN and F glycoproteins of the live-attenuated PIV3 cp45 vaccine virus with their PIV1 counterparts

1 reference

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7 January 2021

The two amino acid substitutions in the L protein of cpts530/1009, a live-attenuated respiratory syncytial virus candidate vaccine, are independent temperature-sensitive and attenuation mutations

1 reference

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7 January 2021

A point mutation in the Sendai virus accessory C proteins attenuates virulence for mice, but not virus growth in cell culture

1 reference

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7 January 2021

Isolation of an avirulent mutant of Sendai virus with two amino acid mutations from a highly virulent field strain through adaptation to LLC-MK2 cells

1 reference

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An influenza A live attenuated reassortant virus possessing three temperature-sensitive mutations in the PB2 polymerase gene rapidly loses temperature sensitivity following replication in hamsters

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Genetic factors associated with loss of the temperature-sensitive phenotype of the influenza A/Alaska/77-ts-1A2 recombinant during growth in vivo

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Evaluation of a live, cold-passaged, temperature-sensitive, respiratory syncytial virus vaccine candidate in infancy

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7 January 2021

Principles underlying the development and use of live attenuated cold-adapted influenza A and B virus vaccines

1 reference

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A 36 nucleotide deletion mutation in the coding region of the NS1 gene of an influenza A virus RNA segment 8 specifies a temperature-dependent host range phenotype

1 reference

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African green monkeys provide a useful nonhuman primate model for the study of human parainfluenza virus types-1, -2, and -3 infection

1 reference

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7 January 2021

Human parainfluenza virus type I (HPIV1) vaccine candidates designed by reverse genetics are attenuated and efficacious in African green monkeys

1 reference

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Identification of mutations contributing to the temperature-sensitive, cold-adapted, and attenuation phenotypes of the live-attenuated cold-passage 45 (cp45) human parainfluenza virus 3 candidate vaccine.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Addition of a missense mutation present in the L gene of respiratory syncytial virus (RSV) cpts530/1030 to RSV vaccine candidate cpts248/404 increases its attenuation and temperature sensitivity.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.043

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic instability of live, attenuated human immunodeficiency virus type 1 vaccine strains

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.043

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/J.VACCINE.2005.04.043

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

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