(Q40408487)

20 September 2017

TrkA induces apoptosis of neuroblastoma cells and does so via a p53-dependent mechanism (English)

1 reference

20 September 2017

1 reference

7

Freda D Miller

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20 September 2017

8

David R Kaplan

1 reference

20 September 2017

Jean-François Lavoie

1

1 reference

20 September 2017

Lynne Lesauteur

2

1 reference

20 September 2017

Judi Kohn

3

1 reference

20 September 2017

Josee Wong

4

1 reference

20 September 2017

Olivia Furtoss

5

1 reference

20 September 2017

Carol J Thiele

6

1 reference

20 September 2017

language of work or name

English

0 references

publication date

16 June 2005

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Journal of Biological Chemistry

20 September 2017

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20 September 2017

280

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20 September 2017

32

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20 September 2017

29199-29207

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Human neuroblastomas with unfavorable biologies express high levels of brain-derived neurotrophic factor mRNA and a variety of its variants

20 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Expression and function of TRK-B and BDNF in human neuroblastomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Association between high levels of expression of the TRK gene and favorable outcome in human neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Brain-derived neurotrophic factor promotes survival and chemoprotection of human neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Expression of trkA cDNA in neuroblastomas mediates differentiation in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Neurotrophin signal transduction in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Chromosomal aberrations in human neuroblastomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

The fine structure of continuous human neuroblastoma lines SK-N-SH, SK-N-BE(2), and SK-N-MC

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

The TrkB-Shc site signals neuronal survival and local axon growth via MEK and P13-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Overexpression of the trk tyrosine kinase rapidly accelerates nerve growth factor-induced differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

TrkA activation is sufficient to rescue axotomized cholinergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

NGF and neurotrophin-3 both activate TrkA on sympathetic neurons but differentially regulate survival and neuritogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Neuroblastoma: biological insights into a clinical enigma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Bcl-2 family proteins as targets for anticancer drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Cytoplasmic sequestration of wild-type p53 protein impairs the G1 checkpoint after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

p53 cellular localization and function in neuroblastoma: evidence for defective G(1) arrest despite WAF1 induction in MYCN-amplified cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Activation of trk-A but not trk-B signal transduction pathway inhibits growth of neuroblastoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

p53 suppresses the activation of the Bcl-2 promoter by the Brn-3a POU family transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Negative regulation of bcl-2 expression by p53 in hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

21 January 2018

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Conversion of Bcl-2 to a Bax-like death effector by caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Parc: a cytoplasmic anchor for p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Dietary exposure to soy or whey proteins alters colonic global gene expression profiles during rat colon tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

c-abl is involved in the association of p53 and trk A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Direct interaction of nerve growth factor receptor, TrkA, with non-receptor tyrosine kinase, c-Abl, through the activation loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Association of the Abl tyrosine kinase with the Trk nerve growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Deacetylation of p53 after nerve growth factor treatment in PC12 cells as a post-translational modification mechanism of neurotrophin-induced tumor suppressor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Microarray analysis reveals differential gene expression patterns and regulation of single target genes contributing to the opposing phenotype of TrkA- and TrkB-expressing neuroblastomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Altered expression of cell cycle genes distinguishes aggressive neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

A novel apoptotic pathway induced by nerve growth factor-mediated TrkA activation in medulloblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

Trk receptor tyrosine kinases: a bridge between cancer and neural development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502364200

21 January 2018

Identifiers

DOI

10.1074/JBC.M502364200

1 reference

20 September 2017

1 reference