(Q40423816)

20 September 2017

1 reference

title

ZD1694 (Tomudex): a new thymidylate synthase inhibitor with activity in colorectal cancer (English)

1 reference

20 September 2017

ZD1694 (Tomudex): A new thymidylate synthase inhibitor with activity in colorectal cancer (English)

1 reference

https://api.crossref.org/works/10.1016/0959-8049(95)00166-G

19 May 2024

1 reference

A. L. Jackman

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7577036

19 May 2024

D. C. Farrugia

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7577036

19 May 2024

W. Gibson

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7577036

19 May 2024

R. Kimbell

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7577036

19 May 2024

K. R. Harrap

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7577036

19 May 2024

T. C. Stephens

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7577036

19 May 2024

M. Azab

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7577036

19 May 2024

F. T. Boyle

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7577036

19 May 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7577036

19 May 2024

publication date

1 July 1995

1 reference

full work available at URL

20 September 2017

https://api.elsevier.com/content/article/PII:095980499500166G?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/0959-8049(95)00166-G

https://api.elsevier.com/content/article/PII:095980499500166G?httpAccept=text/plain

19 May 2024

1 reference

https://api.crossref.org/works/10.1016/0959-8049(95)00166-G

European Journal of Cancer

19 May 2024

published in

1 reference

20 September 2017

volume

31A

1 reference

20 September 2017

issue

7-8

1 reference

20 September 2017

page(s)

1277-1282

1 reference

Preclinical and clinical aspects of biomodulation of 5-fluorouracil

20 September 2017

cites work

2

1 reference

https://api.crossref.org/works/10.1016/0959-8049(95)00166-G

Improvements in fluorouracil chemotherapy?

19 May 2024

3

1 reference

https://api.crossref.org/works/10.1016/0959-8049(95)00166-G

A phase III trial of 5-fluorouracil and leucovorin in the treatment of advanced colorectal cancer. A Mayo Clinic/North Central Cancer Treatment Group study

19 May 2024

4

1 reference

https://api.crossref.org/works/10.1016/0959-8049(95)00166-G

Severe and fatal toxic effects observed in treatment with high- and low-dose leucovorin plus 5-fluorouracil for colorectal carcinoma

19 May 2024

5

1 reference

https://api.crossref.org/works/10.1016/0959-8049(95)00166-G

Novel mechanism(s) of resistance to 5-fluorouracil in human colon cancer (HCT-8) sublines following exposure to two different clinically relevant dose schedules

19 May 2024

6

1 reference

https://api.crossref.org/works/10.1016/0959-8049(95)00166-G

A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: a Mid-Atlantic Oncology Program Study

19 May 2024

7

1 reference

https://api.crossref.org/works/10.1016/0959-8049(95)00166-G

A potent antitumour quinazoline inhibitor of thymidylate synthetase: Synthesis, biological properties and therapeutic results in mice

19 May 2024

8

1 reference

https://api.crossref.org/works/10.1016/0959-8049(95)00166-G

Quinazoline antifolates inhibiting thymidylate synthase: 2-desamino derivatives with enhanced solubility and potency

19 May 2024

10

1 reference

https://api.crossref.org/works/10.1016/0959-8049(95)00166-G

Activity of the thymidylate synthase inhibitor 2-desamino-N10-propargyl-5,8-dideazafolic acid and related compounds in murine (L1210) and human (W1L2) systems in vitro and in L1210 in vivo

19 May 2024

11

1 reference

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Quinazoline antifolate thymidylate synthase inhibitors: alkyl, substituted alkyl, and aryl substituents in the C2 position

19 May 2024

12

1 reference

https://api.crossref.org/works/10.1016/0959-8049(95)00166-G

The biochemical pharmacology of the thymidylate synthase inhibitor, 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583)

19 May 2024

13

1 reference

https://api.crossref.org/works/10.1016/0959-8049(95)00166-G

ICI D1694, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo: a new agent for clinical study

19 May 2024

14

1 reference

https://api.crossref.org/works/10.1016/0959-8049(95)00166-G

Mechanisms of acquired resistance to the quinazoline thymidylate synthase inhibitor ZD1694 (Tomudex) in one mouse and three human cell lines

19 May 2024

15

1 reference

https://api.crossref.org/works/10.1016/0959-8049(95)00166-G

The measurement of polyglutamate metabolites of the thymidylate synthase inhibitoR, ICI D1694, in mouse and human cultured cells

19 May 2024

16

1 reference

https://api.crossref.org/works/10.1016/0959-8049(95)00166-G

Modulation of anti-metabolite effects. Effects of thymidine on the efficacy of the quinazoline-based thymidylate synthetase inhibitor, CB3717

19 May 2024

19

1 reference

https://api.crossref.org/works/10.1016/0959-8049(95)00166-G

Cytotoxicity of antifolate inhibitors of thymidylate and purine synthesis to WiDr colonic carcinoma cells

19 May 2024

20

1 reference

https://api.crossref.org/works/10.1016/0959-8049(95)00166-G

The pharmacokinetics of the quinazoline antifolate ICI D 1694 in mice and rats

19 May 2024

21

1 reference

https://api.crossref.org/works/10.1016/0959-8049(95)00166-G

ICI D1694, an inhibitor of thymidylate synthase for clinical study

19 May 2024

24

1 reference

https://api.crossref.org/works/10.1016/0959-8049(95)00166-G

The toxicity of ICI D1694 in man and mouse

19 May 2024

26

1 reference

https://api.crossref.org/works/10.1016/0959-8049(95)00166-G

19 May 2024

Identifiers

1 reference

release_cky5xdofpvc5zehr7gqk5axndu

20 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/cky5xdofpvc5zehr7gqk5axndu

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference