(Q40434681)

20 September 2017

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title

K-ras mutation and pancreatic adenocarcinoma (English)

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20 September 2017

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1

Caldas C

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20 September 2017

Kern SE

2

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20 September 2017

1 August 1995

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International Journal of Pancreatology

20 September 2017

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20 September 2017

18

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20 September 2017

1-6

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20 September 2017

1

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p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions

20 September 2017

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12 December 2020

Pancreatic neoplasia induced by ras expression in acinar cells of transgenic mice.

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12 December 2020

Frequent glycine-to-aspartic acid mutations at codon 12 of c-Ki-ras gene in human pancreatic cancer in Japanese

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12 December 2020

Protein farnesyltransferase inhibitors block the growth of ras-dependent tumors in nude mice

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12 December 2020

Factors influencing survival after pancreaticoduodenectomy for pancreatic cancer

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12 December 2020

Species-specific differences in tumorigenesis and senescence.

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12 December 2020

Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

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12 December 2020

Pancreatic ductal adenocarcinomas induced in Syrian hamsters by N-nitrosobis(2-oxopropyl)amine contain a c-Ki-ras oncogene with a point-mutated codon 12.

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12 December 2020

Identification of K-ras oncogene mutations in the pure pancreatic juice of patients with ductal pancreatic cancers.

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12 December 2020

K-ras and p53 gene mutations in pancreatic cancer: ductal and nonductal tumors progress through different genetic lesions.

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12 December 2020

Relation of pancreatic duct hyperplasia to carcinoma

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12 December 2020

KRAS codon 12 mutations occur very frequently in pancreatic adenocarcinomas

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12 December 2020

Multiple K-ras codon 12 mutations in cholangiocarcinomas demonstrated with a sensitive polymerase chain reaction technique.

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12 December 2020

Pancreatic duct hyperplasia and cancer

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12 December 2020

Ki-ras mutations in pancreatic secretions and aspirates from two patients without pancreatic cancer

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12 December 2020

A dot-blot screening procedure for mutated ras oncogenes using synthetic oligodeoxynucleotides

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12 December 2020

Three different mutations in codon 61 of the human N-ras gene detected by synthetic oligonucleotide hybridization.

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12 December 2020

Detection of ras gene mutations in pancreatic juice and peripheral blood of patients with pancreatic adenocarcinoma.

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12 December 2020

Direct sequencing analysis of exon 1 of the c-K-ras gene shows a low frequency of mutations in human pancreatic adenocarcinomas

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12 December 2020

A method to detect and characterize point mutations in transcribed genes: amplification and overexpression of the mutant c-Ki-ras allele in human tumor cells

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12 December 2020

Allelotype of pancreatic adenocarcinoma

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12 December 2020

Detection of K-ras mutations in mucinous pancreatic duct hyperplasia from a patient with a family history of pancreatic carcinoma.

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12 December 2020

Molecular determinants of dysplasia in colorectal lesions.

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12 December 2020

Frequent c-Ki-ras oncogene activation in mucous cell hyperplasias of pancreas suffering from chronic inflammation

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12 December 2020

Predisposition to neoplastic transformation caused by gene replacement of H-ras1.

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12 December 2020

Frequent somatic mutations of the APC gene in human pancreatic cancer

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12 December 2020

Altered growth of human colon cancer cell lines disrupted at activated Ki-ras

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12 December 2020

Detection of K-ras mutations in the stool of patients with pancreatic adenocarcinoma and pancreatic ductal hyperplasia

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12 December 2020

T24 human bladder carcinoma oncogene is an activated form of the normal human homologue of BALB- and Harvey-MSV transforming genes

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12 December 2020

A genetic model for colorectal tumorigenesis

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12 December 2020

Clinical application of ras gene mutation for diagnosis of pancreatic adenocarcinoma

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12 December 2020

The ras gene family and human carcinogenesis

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12 December 2020

Intraductal proliferation in the pancreas and its relationship to human and experimental carcinogenesis.

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12 December 2020

Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor

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12 December 2020

Morphological lesions associated with human primary invasive nonendocrine pancreas cancer

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12 December 2020

Rapid and sensitive nonradioactive detection of mutant K-ras genes via 'enriched' PCR amplification

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12 December 2020

K-ras mutations in putative preneoplastic lesions in human colon

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12 December 2020

Detection of point mutations in the Kirsten-ras oncogene provides evidence for the multicentricity of pancreatic carcinoma

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12 December 2020

Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes

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12 December 2020

Soluble normal and mutated DNA sequences from single-copy genes in human blood

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12 December 2020

Activation of the c-K-ras oncogene in a human pancreas carcinoma

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12 December 2020

Detection of c-K-ras mutations in fine needle aspirates from human pancreatic adenocarcinomas.

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12 December 2020

Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors

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12 December 2020

The clonal evolution of tumor cell populations

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12 December 2020

High frequency of Ki-ras codon 12 mutations in pancreatic adenocarcinomas

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12 December 2020

K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization

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12 December 2020

Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells

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12 December 2020

K-ras mutation is an early event in pancreatic duct carcinogenesis in the Syrian golden hamster

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12 December 2020

Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer.

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12 December 2020

Ras gene mutations in intraductal papillary neoplasms of the pancreas. Analysis in five cases

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12 December 2020

Inactivation of both APC alleles in human and mouse tumors

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12 December 2020

K-ras gene mutation as a pathogenetic and diagnostic marker in human cancer

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12 December 2020

Detection of c-Ki-ras mutation by PCR/RFLP analysis and diagnosis of pancreatic adenocarcinomas

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12 December 2020

Distinguishing Pancreatic Carcinoma From Other Periampullary Carcinomas by Analysis of Mutations in the Kirsten-ras Oncogene

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12 December 2020

Clonality: more than just a tumor-progression model

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12 December 2020

Transforming genes of human bladder and lung carcinoma cell lines are homologous to the ras genes of Harvey and Kirsten sarcoma viruses

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12 December 2020

c-Ki-ras point mutations in ductectatic-type mucinous cystic neoplasms of the pancreas.

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12 December 2020

ras oncogenes in human cancer: a review

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12 December 2020

PCR-based approaches for detection of mutated ras genes

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12 December 2020

A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

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12 December 2020

Detection of K-ras mutations in pancreatic and hepatic neoplasms by non-isotopic mismatched polymerase chain reaction

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12 December 2020

Frequent loss of expression of the potential tumor suppressor gene DCC in ductal pancreatic adenocarcinoma

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12 December 2020

Frequency and types of point mutation at the 12th codon of the c-Ki-ras gene found in pancreatic cancers from Japanese patients.

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12 December 2020

Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene

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12 December 2020

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12 December 2020

Identifiers

0 references

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PubMed ID

7594765